Last update
5/23/2025

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 1 Review
8.5

Top Medical Research Studies

9
Vitamin C aids stroke rehabilitation
We explored how vitamin C stimulation affects the recovery of stroke patients suffering from dysphagia, a condition that makes swallowing difficult. In a carefully designed study involving 120 stroke patients, we divided them into two groups: one received traditional swallowing training, while the other group was given vitamin C stimulation alongside their training.

Our findings highlighted that those who received vitamin C showed marked improvements in their ability to swallow, as reflected in assessments such as the water swallow test and video fluoroscopic swallowing study. Additionally, we observed enhancements in their nutritional status and immune function, measured by indices like serum albumin and immunoglobulins.

Overall, it seems that vitamin C isn’t just a vitamin; it may play a vital role in helping stroke patients recover more effectively from dysphagia. This evidence supports using vitamin C as a beneficial component in stroke rehabilitation plans.
Read More
We investigated the potential of high-dose vitamin C as a treatment for stroke, focusing on its ability to protect the brain through genetic changes. Our research involved administering ascorbate, the reduced form of vitamin C, to adult mice after a stroke, and we noted it significantly increased the activity of TET3, an enzyme linked to gene regulation. This increase also led to higher levels of a crucial marker called 5hmC, which is believed to play a role in neuroprotection.

Notably, treatment with ascorbate resulted in reduced brain infarcts, or areas of dead tissue, following a stroke. Additionally, we observed that vitamin C helped lower markers of oxidative stress and apoptosis, which is a type of programmed cell death. Furthermore, the mice displayed improvements in both motor skills and cognitive function, indicating that vitamin C may facilitate recovery from stroke.

Our findings suggest that vitamin C could be particularly beneficial for older mice and those with conditions like hypertension and diabetes, showing promising therapeutic effects even when administered a few hours post-stroke. In summary, high-dose vitamin C appears to have robust neuroprotective properties, making it a potential treatment option for stroke injuries.
Read More
7
Vitamin C's role in stroke risk
Our study looked into how vitamin C levels in the blood could influence the risk of suffering a stroke. Recent research has suggested that higher vitamin C might provide some protective benefits, particularly against specific types of strokes, such as cardioembolic stroke.

Using data from a large genome-wide meta-analysis, we aimed to determine if there's a causal relationship between vitamin C and stroke risks. We found that while higher vitamin C levels seemed to potentially reduce the risk of cardioembolic strokes, there were no significant effects observed on other types of cardiovascular diseases or strokes.

This suggests that the benefits of vitamin C may not extend broadly to all forms of stroke. Therefore, more comprehensive studies are necessary to further understand these relationships and identify the underlying processes involved.
Read More

Most Useful Reviews

9
Improved recovery noted
45 people found this helpful
Super Vitamin C was a lifesaver for us. I must thank Tim Ferriss for his recommendation. After my Mum suffered a stroke and spent five days in ICU, I mixed two of these with Emergen-C in her water, and she managed to fend off a cold. I also gave it to my son, who quickly recovered from a cough. My husband's month-long cough cleared up as well. This product works, and it’s essential for our family, especially during tough times.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
  • All Researches
9
Vitamin C aids stroke rehabilitation
We explored how vitamin C stimulation affects the recovery of stroke patients suffering from dysphagia, a condition that makes swallowing difficult. In a carefully designed study involving 120 stroke patients, we divided them into two groups: one received traditional swallowing training, while the other group was given vitamin C stimulation alongside their training.

Our findings highlighted that those who received vitamin C showed marked improvements in their ability to swallow, as reflected in assessments such as the water swallow test and video fluoroscopic swallowing study. Additionally, we observed enhancements in their nutritional status and immune function, measured by indices like serum albumin and immunoglobulins.

Overall, it seems that vitamin C isn’t just a vitamin; it may play a vital role in helping stroke patients recover more effectively from dysphagia. This evidence supports using vitamin C as a beneficial component in stroke rehabilitation plans.
Read More
We investigated the potential of high-dose vitamin C as a treatment for stroke, focusing on its ability to protect the brain through genetic changes. Our research involved administering ascorbate, the reduced form of vitamin C, to adult mice after a stroke, and we noted it significantly increased the activity of TET3, an enzyme linked to gene regulation. This increase also led to higher levels of a crucial marker called 5hmC, which is believed to play a role in neuroprotection.

Notably, treatment with ascorbate resulted in reduced brain infarcts, or areas of dead tissue, following a stroke. Additionally, we observed that vitamin C helped lower markers of oxidative stress and apoptosis, which is a type of programmed cell death. Furthermore, the mice displayed improvements in both motor skills and cognitive function, indicating that vitamin C may facilitate recovery from stroke.

Our findings suggest that vitamin C could be particularly beneficial for older mice and those with conditions like hypertension and diabetes, showing promising therapeutic effects even when administered a few hours post-stroke. In summary, high-dose vitamin C appears to have robust neuroprotective properties, making it a potential treatment option for stroke injuries.
Read More
8
Vitamin C reduces stroke risk
We examined how vitamin C impacts the risk of stroke in our recent analysis. By employing a method called Mendelian randomization, we could better understand the potential causal relationship between vitamin C intake and stroke. This approach helps us avoid some common pitfalls found in traditional observational studies, such as confounding factors.

Our findings revealed that higher levels of vitamin C are associated with a reduced risk of cardioembolic stroke, which is a type of stroke caused by a blood clot that reaches the brain. Specifically, we observed a notable decrease in risk, with an odds ratio of 0.759. This suggests that ensuring adequate vitamin C intake could be beneficial for stroke prevention.

While we found strong evidence supporting vitamin C's protective role, it's crucial to consider that the context of these nutrients is complex. Nonetheless, our results propose that incorporating vitamin C into a balanced diet may help in lowering the risk of certain types of stroke, making it an important focus for health strategies aimed at prevention.
Read More
7
Vitamin C's role in stroke risk
Our study looked into how vitamin C levels in the blood could influence the risk of suffering a stroke. Recent research has suggested that higher vitamin C might provide some protective benefits, particularly against specific types of strokes, such as cardioembolic stroke.

Using data from a large genome-wide meta-analysis, we aimed to determine if there's a causal relationship between vitamin C and stroke risks. We found that while higher vitamin C levels seemed to potentially reduce the risk of cardioembolic strokes, there were no significant effects observed on other types of cardiovascular diseases or strokes.

This suggests that the benefits of vitamin C may not extend broadly to all forms of stroke. Therefore, more comprehensive studies are necessary to further understand these relationships and identify the underlying processes involved.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved recovery noted
45 people found this helpful
Super Vitamin C was a lifesaver for us. I must thank Tim Ferriss for his recommendation. After my Mum suffered a stroke and spent five days in ICU, I mixed two of these with Emergen-C in her water, and she managed to fend off a cold. I also gave it to my son, who quickly recovered from a cough. My husband's month-long cough cleared up as well. This product works, and it’s essential for our family, especially during tough times.
Read More

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References

  1. Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. 10.3390/nu16172818
  2. Wang J, Chang E, Jiang Y. Effects of vitamin C stimulation on rehabilitation of dysphagia after stroke: a randomized trial. Eur J Phys Rehabil Med. 2022;58:558. 10.23736/S1973-9087.22.07337-3
  3. Morris-Blanco KC, Chokkalla AK, Kim T, Bhatula S, Bertogliat MJ, et al. High-Dose Vitamin C Prevents Secondary Brain Damage After Stroke via Epigenetic Reprogramming of Neuroprotective Genes. Transl Stroke Res. 2022;13:1017. 10.1007/s12975-022-01007-6
  4. Chen L, Sun X, Wang Z, Lu Y, Chen M, et al. The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease: A Mendelian randomization study. Clin Nutr. 2021;40:5327. 10.1016/j.clnu.2021.08.020
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