Last update
3/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Good
Based on 22 Reviews
8.7
Top Medical Research Studies
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
8
We examined how megadose Vitamin C affects cold and flu symptoms in a controlled study with students.
In this research, 252 students received hourly doses of 1000 mg mostly at the onset of symptoms, while 463 students served as a control group, treated with standard pain relievers.
Despite some positive outcomes observed, the study results indicate that Vitamin C did not significantly affect the prevention or relief of these symptoms overall, raising questions about its effectiveness in combatting the flu.
In this research, 252 students received hourly doses of 1000 mg mostly at the onset of symptoms, while 463 students served as a control group, treated with standard pain relievers.
Despite some positive outcomes observed, the study results indicate that Vitamin C did not significantly affect the prevention or relief of these symptoms overall, raising questions about its effectiveness in combatting the flu.
Read More
8
Vitamin C triterpene flu inhibitors
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
Most Useful Reviews
9
Flu symptoms eradicated
732 people found this helpful
I enjoyed using this product. I used it to treat persistent sinus pain, sore throat, and cough, and I had great results. After taking two packets per day for two days, all my flu symptoms disappeared. Unexpectedly, I also noticed my long-term blurry vision improved remarkably. I was thrilled. Despite my health issues, I found I was having deeper sleep and more energy. This product effectively tackled my flu and provided many additional benefits.
Read More
9
Life-saving effects
76 people found this helpful
This product has been invaluable. When my husband was hospitalised due to severe illness, we managed to administer high-dose vitamin C through a feeding tube. The improvement was astounding, as he was off the ventilator in 18 days. We continue to use it to ward off colds and flu. Its effectiveness against respiratory illnesses is remarkable.
Read More
9
Quick flu recovery
22 people found this helpful
Stock up for flu season. This past winter's flu season was brutal, knocking me out with fever and aches for 2 days. Desperate, I looked for a Vitamin C IV option but decided to try this product instead. After starting its use, my runny nose was gone by day four, and I was free of coughing by the third week—usually, it lasts longer for me. I managed to overcome the flu with just one box, which is far cheaper than other options. Now, I keep it stocked for the first signs of illness.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
- All Researches
9
We set out to discover how red ginseng and vitamin C work together to enhance immune cell function and fight off viral infections like the flu. In our investigation, we treated human immune cells and specific types of mice unable to produce vitamin C, looking closely at their reaction to influenza A virus/H1N1.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
Read More
8
Vitamin C triterpene flu inhibitors
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
8
We explored the effectiveness of various drugs on swine flu, focusing on the role of vitamin C. Using advanced modeling techniques, we assessed how well vitamin C interacts with key proteins of the H1N1 virus. The results show that vitamin C forms strong bonds with the virus proteins, suggesting it may be a beneficial treatment option. Other remedies were also tested but didn’t show the same level of interaction. This points to vitamin C as a potential player in fighting H1N1 infections.
Read More
8
We explored the effect of high-dose vitamin C on blood flow reactivity during inflammation. In a study with 36 men, we utilized a placebo-controlled design to administer endotoxin, which triggered flu-like symptoms and decreased vitamin C levels. Following this, we tested how vitamin C improved blood flow responses.
Our findings revealed that vitamin C significantly restored blood flow responses in the forearm after endotoxin administration. This breakthrough suggests potential benefits of vitamin C during inflammatory episodes, inviting further clinical research.
Our findings revealed that vitamin C significantly restored blood flow responses in the forearm after endotoxin administration. This breakthrough suggests potential benefits of vitamin C during inflammatory episodes, inviting further clinical research.
Read More
User Reviews
USERS' SCORE
Good
Based on 22 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Flu symptoms eradicated
732 people found this helpful
I enjoyed using this product. I used it to treat persistent sinus pain, sore throat, and cough, and I had great results. After taking two packets per day for two days, all my flu symptoms disappeared. Unexpectedly, I also noticed my long-term blurry vision improved remarkably. I was thrilled. Despite my health issues, I found I was having deeper sleep and more energy. This product effectively tackled my flu and provided many additional benefits.
Read More
9
Life-saving effects
76 people found this helpful
This product has been invaluable. When my husband was hospitalised due to severe illness, we managed to administer high-dose vitamin C through a feeding tube. The improvement was astounding, as he was off the ventilator in 18 days. We continue to use it to ward off colds and flu. Its effectiveness against respiratory illnesses is remarkable.
Read More
9
Quick flu recovery
22 people found this helpful
Stock up for flu season. This past winter's flu season was brutal, knocking me out with fever and aches for 2 days. Desperate, I looked for a Vitamin C IV option but decided to try this product instead. After starting its use, my runny nose was gone by day four, and I was free of coughing by the third week—usually, it lasts longer for me. I managed to overcome the flu with just one box, which is far cheaper than other options. Now, I keep it stocked for the first signs of illness.
Read More
9
Effective for stubborn flu
21 people found this helpful
I had a stubborn cold/flu since Christmas Day and tried everything to get rid of it. Finally, after ordering Lypo Vitamin C, I felt like a new man within two days. Be aware that it doesn’t mix well with water because of its liposomal nature. I found the best technique is to squeeze it into water and drink it down quickly. Taking it on an empty stomach is better, and while it's potent, it's not a miracle cure. However, it has proven effective.
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9
Flu prevention
18 people found this helpful
***UPDATE: 1-30-13*** I'm still pleased with the results. I increased my workload recently and was around sick children, yet did NOT catch their illnesses. I enjoy increased energy daily and appreciate the convenience of this product. I can't imagine being without it again. I was amazed to recover from the flu in just THREE DAYS, feeling fully productive. This product saved me! My weak immune system usually means close contact leads to illness. However, I felt protected during flu season.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Abioye AI, Bromage S, Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob Health. 2021;6. 10.1136/bmjgh-2020-003176
- Márquez-Domínguez L, Reyes-Leyva J, Herrera-Camacho I, Santos-López G, Scior T. Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus. Molecules. 2020;25. 10.3390/molecules25184248
- Kim H, Jang M, Kim Y, Choi J, Jeon J, et al. Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection. J Pharm Pharmacol. 2016;68:406. 10.1111/jphp.12529
- Wang H, Xu R, Shi Y, Si L, Jiao P, et al. Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors. Eur J Med Chem. 2016;110:376. 10.1016/j.ejmech.2016.01.005
- Cai Y, Li YF, Tang LP, Tsoi B, Chen M, et al. A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice. Biomed Res Int. 2015;2015:675149. 10.1155/2015/675149
- Raja K, Prabahar A, Selvakumar S, Raja TK. In Silico Analysis to Compare the Effectiveness of Assorted Drugs Prescribed for Swine flu in Diverse Medicine Systems. Indian J Pharm Sci. 2014;76:10. PubMed
- Aschauer S, Gouya G, Klickovic U, Storka A, Weisshaar S, et al. Effect of systemic high dose vitamin C therapy on forearm blood flow reactivity during endotoxemia in healthy human subjects. Vascul Pharmacol. 2014;61:25. 10.1016/j.vph.2014.01.007
- Gorton HC, Jarvis K. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections. J Manipulative Physiol Ther. 1999;22:530. PubMed
