Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
USERS' SCORE
Good
Based on 1 Review
8.5
Top Medical Research Studies
9
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
8
We explored the effectiveness of calcium in alleviating heartburn, especially in pregnant women. Our findings highlighted that many expectant mothers experience heartburn due to hormonal changes and the physical pressure of a growing fetus on the stomach.
Calcium-based antacids emerged as an excellent choice for providing relief. Not only do they help manage heartburn symptoms, but they also offer a source of calcium, which is vital for bone health in both mothers and their developing babies.
By ensuring adequate calcium intake through these antacids, we can support maternal health while addressing the discomforts of pregnancy. This dual benefit makes calcium supplementation a practical option for maintaining well-being during this critical time.
Calcium-based antacids emerged as an excellent choice for providing relief. Not only do they help manage heartburn symptoms, but they also offer a source of calcium, which is vital for bone health in both mothers and their developing babies.
By ensuring adequate calcium intake through these antacids, we can support maternal health while addressing the discomforts of pregnancy. This dual benefit makes calcium supplementation a practical option for maintaining well-being during this critical time.
Read More
Most Useful Reviews
9
No heartburn for months
6 people found this helpful
Using it for 6 months already! I've been using this for more than six months without side effects; no heartburn or headaches. I've tried other multivitamins, but this one has been the best for me, allowing me to continue daily use comfortably.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
- All Researches
9
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More
9
We explored the combined effects of calcium from carbonate antacids and extract from the prickly pear plant, Opuntia ficus-indica, on heartburn symptoms. This was investigated through tests designed to mimic conditions in the esophagus during acid reflux. Our main goal was to understand if these ingredients could effectively help in neutralizing stomach acid and safeguarding esophageal cells from damage caused by both acidic and non-acidic reflux.
In our experiments, we found that the carbonate antacids worked to neutralize the acidity, which in turn helped to protect esophageal cells from harm due to low pH levels. Additionally, the prickly pear extract showed promise in reducing irritation from bile acids, as it decreased inflammation markers typically associated with reflux. This dual action of both components suggests that combining them could be an effective way to manage heartburn.
Overall, this study indicates that while calcium plays a role through antacid effects, the inclusion of prickly pear extract enhances the overall protective benefits against heartburn, making it a potentially valuable treatment option for those experiencing gastrointestinal discomfort.
In our experiments, we found that the carbonate antacids worked to neutralize the acidity, which in turn helped to protect esophageal cells from harm due to low pH levels. Additionally, the prickly pear extract showed promise in reducing irritation from bile acids, as it decreased inflammation markers typically associated with reflux. This dual action of both components suggests that combining them could be an effective way to manage heartburn.
Overall, this study indicates that while calcium plays a role through antacid effects, the inclusion of prickly pear extract enhances the overall protective benefits against heartburn, making it a potentially valuable treatment option for those experiencing gastrointestinal discomfort.
Read More
9
We explored how calcium-containing antacids can help relieve heartburn, especially for pregnant women dealing with gastroesophageal reflux disease (GERD). This common issue affects many expectant mothers, causing discomfort and aggravation throughout their pregnancy.
The recommendation suggests starting with lifestyle changes to manage symptoms. But when heartburn is severe, introducing calcium-based antacids shows significant promise in reducing those pesky acid reflux issues. This approach prioritizes the health and safety of both mother and baby while aiming for effective relief from symptoms.
If symptoms persist, other treatments like Sucralfate or histamine-2 receptor antagonists can be considered. However, adding calcium-based antacids early on is a preferred first step for many women. Overall, we can see a clear benefit in using calcium for heartburn management during pregnancy, providing a healthy option for easing discomfort.
The recommendation suggests starting with lifestyle changes to manage symptoms. But when heartburn is severe, introducing calcium-based antacids shows significant promise in reducing those pesky acid reflux issues. This approach prioritizes the health and safety of both mother and baby while aiming for effective relief from symptoms.
If symptoms persist, other treatments like Sucralfate or histamine-2 receptor antagonists can be considered. However, adding calcium-based antacids early on is a preferred first step for many women. Overall, we can see a clear benefit in using calcium for heartburn management during pregnancy, providing a healthy option for easing discomfort.
Read More
9
This study aimed to assess how effectively GutsyGum™, a chewing gum containing calcium carbonate along with licorice extract, papain, and apple cider vinegar, alleviates heartburn after consuming a refluxogenic meal. We conducted a double-blind, placebo-controlled crossover trial with 24 participants who had a history of gastro-esophageal reflux (GER). They were asked to chew either GutsyGum™ or a placebo after the meal, and their GER symptoms were measured using visual analogue scales over a four-hour period.
The results revealed that GutsyGum™ significantly reduced heartburn and acid reflux symptoms compared to the placebo. Specifically, the adjusted heartburn score was lower in those chewing GutsyGum™. However, when it came to other symptoms like nausea and belching, we didn't find significant differences. Although there was a trend indicating less pain with GutsyGum™, it didn't reach statistical significance.
Importantly, while calcium carbonate is a component of GutsyGum™, the effectiveness we noted comes from the combination of ingredients, making it challenging to pinpoint calcium's isolated role in reducing heartburn.
The results revealed that GutsyGum™ significantly reduced heartburn and acid reflux symptoms compared to the placebo. Specifically, the adjusted heartburn score was lower in those chewing GutsyGum™. However, when it came to other symptoms like nausea and belching, we didn't find significant differences. Although there was a trend indicating less pain with GutsyGum™, it didn't reach statistical significance.
Importantly, while calcium carbonate is a component of GutsyGum™, the effectiveness we noted comes from the combination of ingredients, making it challenging to pinpoint calcium's isolated role in reducing heartburn.
Read More
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
No heartburn for months
6 people found this helpful
Using it for 6 months already! I've been using this for more than six months without side effects; no heartburn or headaches. I've tried other multivitamins, but this one has been the best for me, allowing me to continue daily use comfortably.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. doi:10.1016/j.gie.2019.11.028
- Hayashi A, Taki Y, Arai K, Sato S, Higashizono K, et al. Esophageal ulcer related to zinc deficiency following a total gastrectomy. Nutrition. 2023;110:111999. doi:10.1016/j.nut.2023.111999
- Lehner MD, Scheyhing U, Elsässer J. A combination of carbonates and Opuntia ficus-indica extract protects esophageal cells against simulated acidic and non-acidic reflux in vitro. Sci Rep. 2024;14:22355. doi:10.1038/s41598-024-74047-7
- Altuwaijri M. Evidence-based treatment recommendations for gastroesophageal reflux disease during pregnancy: A review. Medicine (Baltimore). 2022;101:e30487. doi:10.1097/MD.0000000000030487
- Christensen CB, Soelberg J, Jäger AK. Antacid activity of Laportea aestuans (L.) Chew. J Ethnopharmacol. 2015;171:1. doi:10.1016/j.jep.2015.05.026
- Brown R, Sam CH, Green T, Wood S. Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal. J Diet Suppl. 2015;12:138. doi:10.3109/19390211.2014.950783
- Sulz MC, Manz M, Grob P, Meier R, Drewe J, et al. Comparison of two antacid preparations on intragastric acidity--a two-centre open randomised cross-over placebo-controlled trial. Digestion. 2007;75:69.
- Thomas M, Weisman SM. Calcium supplementation during pregnancy and lactation: effects on the mother and the fetus. Am J Obstet Gynecol. 2006;194:937.
