Overview
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
5.6
USERS' SCORE
Good
Based on 1 Review
8.5
Top Medical Research Studies
8
We conducted a double-masked, placebo-controlled trial involving 15,832 Nepali women to explore how vitamin A and beta-carotene supplementation affects pregnancy-related nausea and overall illness symptoms. Our observations showed that while there was no noticeable impact during the early stages of pregnancy, vitamin A supplementation made a significant difference in late pregnancy.
Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.
Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.
Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Read More
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
7
Zinc treatment reduces nausea risk
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
Most Useful Reviews
9
Adjust dosage timing
5 people found this helpful
UPDATED: To avoid nausea, take right after your biggest meal of the day. I once experienced nausea when taking these on an empty stomach, but if taken right after dinner, I feel fine. The nausea issue seems common, but a full stomach before taking the pill may help eliminate it for you.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
5.6
- All Researches
8
We conducted a double-masked, placebo-controlled trial involving 15,832 Nepali women to explore how vitamin A and beta-carotene supplementation affects pregnancy-related nausea and overall illness symptoms. Our observations showed that while there was no noticeable impact during the early stages of pregnancy, vitamin A supplementation made a significant difference in late pregnancy.
Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.
Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.
Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Read More
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
7
Zinc treatment reduces nausea risk
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
7
We explored the impact of zinc acetate dihydrate on several symptoms, including nausea, through a comprehensive study that assessed its safety and effectiveness for treating hypozincemia over a 52-week period. From the data collected, we observed an overall adverse reaction rate of 9.4%, with nausea reported in 1.4% of patients.
Despite nausea being a concern, the benefit of zinc acetate dihydrate for other indications was notable, with an efficacy rate of 83%. For patients experiencing symptoms such as pressure ulcers or stomatitis, the effectiveness was strikingly high. However, the specific effect of zinc on nausea is not definitively isolated within the study results, making it hard to gauge its direct and unique benefits.
In essence, while zinc acetate dihydrate shows promise for a variety of symptoms, including nausea, the evidence does not conclusively highlight its effectiveness for this particular issue on its own. Overall, it appears that zinc treatment can contribute positively to addressing several related health problems.
Despite nausea being a concern, the benefit of zinc acetate dihydrate for other indications was notable, with an efficacy rate of 83%. For patients experiencing symptoms such as pressure ulcers or stomatitis, the effectiveness was strikingly high. However, the specific effect of zinc on nausea is not definitively isolated within the study results, making it hard to gauge its direct and unique benefits.
In essence, while zinc acetate dihydrate shows promise for a variety of symptoms, including nausea, the evidence does not conclusively highlight its effectiveness for this particular issue on its own. Overall, it appears that zinc treatment can contribute positively to addressing several related health problems.
Read More
5
We explored how vitamin D levels affect nausea and other premenstrual symptoms (PMS) while considering the influence of genetics. Our study involved 716 women between the ages of 20 and 29, who provided blood samples to measure their vitamin D status and completed questionnaires about their PMS experiences.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Adjust dosage timing
5 people found this helpful
UPDATED: To avoid nausea, take right after your biggest meal of the day. I once experienced nausea when taking these on an empty stomach, but if taken right after dinner, I feel fine. The nausea issue seems common, but a full stomach before taking the pill may help eliminate it for you.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Christian P, West KP, Khatry SK, Katz J, LeClerq SC, et al. Vitamin A or beta-carotene supplementation reduces symptoms of illness in pregnant and lactating Nepali women. J Nutr. 2000;130:2675.
- Foessleitner P, Rager L, Mikula F, Hager M, Granser S, et al. The Role of hCG and Histamine in Emesis Gravidarum and Use of a Chewing Gum Containing Vitamin C as a Treatment Option: A Double-Blinded, Randomized, Controlled Trial. J Clin Med. 2024;13. doi:10.3390/jcm13175099
- Koch KL, Parkman HP, Yates KP, Van Natta ML, Grover M, et al. Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity. Dig Dis Sci. 2024;69:2904. doi:10.1007/s10620-024-08520-8
- Jarosz AC, Noori D, Zeitoun T, Garcia-Bailo B, El-Sohemy A. Variation in the vitamin D receptor gene, plasma 25-hydroxyvitamin D, and risk of premenstrual symptoms. Genes Nutr. 2021;16:15. doi:10.1186/s12263-021-00696-2
- Asaoka D, Ishihara T, Ezoe S, Hamada I, Kitamura M, et al. Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia. J Trace Elem Med Biol. 2025;87:127558. doi:10.1016/j.jtemb.2024.127558
- Ezoe S, Ishihara T, Hosogai T, Kokubo T. Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan. Pharmazie. 2024;79:29. doi:10.1691/ph.2024.3630
- Parvizi A, Haddadi S, Akbari M, Akbarpour M, Taghipour Rudsari F, et al. Comparing the Effect of Zinc-impregnated Pharyngeal Packs with Conventional Methods on the Level of Sore Throat Among Patients Undergoing Septorhinoplasty. Anesth Pain Med. 2022;12:e127262. doi:10.5812/aapm-127262
- Nuzhat S, Ahmed T, Alam J, Billal SM, Khan AI, et al. New formulation zinc sulphate acceptability and adherence in children with acute diarrhoea: A prospective, open-label, interventional study in Bangladesh. J Paediatr Child Health. 2022;58:1215. doi:10.1111/jpc.15953
