5/13/2025
Last update
5/13/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Ineffective
Based on 3 Researches
4.3
USERS' SCORE
Good
Based on 1 Review
8.5
Top Medical Research Studies
9
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
4
We assessed the impact of vitamin D on leg cramps experienced during pregnancy, referring to data from various studies. One of the key findings was that vitamin D treatment showed little to no difference when it came to reducing the frequency of leg cramps.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
Read More
0
We conducted a double-blind, randomized controlled trial to explore whether Vitamin D and calcium-Vitamin D supplements could help reduce leg cramps in pregnant women. Our study involved 126 participants aged 18 to 35, all experiencing a minimum of two leg cramps per week. Over the course of 42 days, participants took either a Vitamin D pill, calcium with Vitamin D, or a placebo.
We closely monitored the frequency, duration, and intensity of leg cramps before the intervention and during the third and sixth weeks of treatment. Despite our efforts and careful analysis, the results were clear: neither the Vitamin D nor the calcium-Vitamin D supplements made a meaningful difference in leg cramps.
This finding indicates that these popular supplements may not be effective for alleviating leg cramps during pregnancy, at least within the timeframe of our study. It's important for expecting mothers to consider this information when seeking relief from leg cramps.
We closely monitored the frequency, duration, and intensity of leg cramps before the intervention and during the third and sixth weeks of treatment. Despite our efforts and careful analysis, the results were clear: neither the Vitamin D nor the calcium-Vitamin D supplements made a meaningful difference in leg cramps.
This finding indicates that these popular supplements may not be effective for alleviating leg cramps during pregnancy, at least within the timeframe of our study. It's important for expecting mothers to consider this information when seeking relief from leg cramps.
Read More
Most Useful Reviews
8.5
No more issues
92 people found this helpful
I've been using this Vitamin D3 product for four months and feel great. It helps with my focus, memory, and importantly, I've experienced no leg cramps. However, I've noticed price fluctuations on Amazon.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 3 Researches
4.3
- All Researches
9
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
4
We assessed the impact of vitamin D on leg cramps experienced during pregnancy, referring to data from various studies. One of the key findings was that vitamin D treatment showed little to no difference when it came to reducing the frequency of leg cramps.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
Read More
0
We conducted a double-blind, randomized controlled trial to explore whether Vitamin D and calcium-Vitamin D supplements could help reduce leg cramps in pregnant women. Our study involved 126 participants aged 18 to 35, all experiencing a minimum of two leg cramps per week. Over the course of 42 days, participants took either a Vitamin D pill, calcium with Vitamin D, or a placebo.
We closely monitored the frequency, duration, and intensity of leg cramps before the intervention and during the third and sixth weeks of treatment. Despite our efforts and careful analysis, the results were clear: neither the Vitamin D nor the calcium-Vitamin D supplements made a meaningful difference in leg cramps.
This finding indicates that these popular supplements may not be effective for alleviating leg cramps during pregnancy, at least within the timeframe of our study. It's important for expecting mothers to consider this information when seeking relief from leg cramps.
We closely monitored the frequency, duration, and intensity of leg cramps before the intervention and during the third and sixth weeks of treatment. Despite our efforts and careful analysis, the results were clear: neither the Vitamin D nor the calcium-Vitamin D supplements made a meaningful difference in leg cramps.
This finding indicates that these popular supplements may not be effective for alleviating leg cramps during pregnancy, at least within the timeframe of our study. It's important for expecting mothers to consider this information when seeking relief from leg cramps.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.5
No more issues
92 people found this helpful
I've been using this Vitamin D3 product for four months and feel great. It helps with my focus, memory, and importantly, I've experienced no leg cramps. However, I've noticed price fluctuations on Amazon.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Luo L, Zhou K, Zhang J, Xu L, Yin W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2020;12:CD010655. 10.1002/14651858.CD010655.pub3
- Mansouri A, Mirghafourvand M, Charandabi SMA, Najafi M. The effect of Vitamin D and calcium plus Vitamin D on leg cramps in pregnant women: A randomized controlled trial. J Res Med Sci. 2017;22:24. 10.4103/1735-1995.200271
- Tan J, Zhu R, Li Y, Wang L, Liao S, et al. Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial. JAMA Intern Med. 2024;184:1443. 10.1001/jamainternmed.2024.5726
