Jarrow Formulas MK-7 Softgel 90 mcg

We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.

By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.

Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.

9.5

Ekg improvement

Most Useful Review

This product has greatly helped with cleaning arteries. My husband, who has undergone three heart procedures, was surprised by how "perfect" his ECG turned out during a check-up after starting it. His blood pressure has also improved markedly, possibly due to less artery blockage, reducing the risk of heart attacks. He occasionally skips a day as it builds up in his system.

Osteoporosis details

SCIENTIFIC SCORE

Possibly Effective

Based on 16 Researches

Vitamin K2 improves bone health

Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.

Most Relevant Research

Our exploration focused on how vitamin K2 supplementation may aid postmenopausal women dealing with osteoporosis, particularly regarding bone mineral density (BMD) and the incidence of fractures over the long term. We meticulously reviewed nine randomized controlled trials with nearly 6,900 participants to gather insightful data on this topic.

The results were promising, revealing that vitamin K2 significantly enhanced lumbar and forearm BMD. Specifically, we observed notable increases in bone density measurements, alongside a reduction in undercarboxylated osteocalcin—a marker associated with bone health, and a significant rise in total osteocalcin.

Although there was an increase in the rate of adverse reactions in the vitamin K2 group, we found no serious side effects stemming from the supplementation. Overall, our study supports the conclusion that vitamin K2 is not only effective but also safe for treating osteoporosis in postmenopausal women. This could provide a welcome option for those looking to improve their bone health.

9.5

Promotes bone health

Most Useful Review

Crucial vitamin for heart and bone health. MK-7 (Menaquinone-7) is an enhanced form of Vitamin K2 that promotes bone health and helps prevent osteoporosis without side effects. I prefer this brand as Jarrow is highly reputable. The suggested intake is one softgel daily, either with food or on an empty stomach. MK-7 helps the body build bone naturally.

Bone Pain details

Research your health! I began using this product after experiencing calcium shifting from my bones to my blood, which my doctor did not address. After speaking with a Vitamin specialist, I started taking MK-7 along with magnesium and vitamin D, which successfully drew calcium back from my blood to my bones. I am thrilled as the bone pain has completely vanished! These vitamins have revitalised me!

Back Pain details

Vitamin K2 boosts back pain recovery

Concurrent Treatment with Vitamin K2 and D3 on Spine Fusion in Patients with Osteoporosis-Associated Lumbar Degenerative Disorders.

Most Relevant Research

We explored how treating patients with osteoporosis with vitamin K2 and D3 could influence back pain and spine fusion rates following surgery. In this study, we included patients who underwent spinal surgery for lumbar degenerative disorders. Some received a combination of vitamin K2, D3, and calcium, while others were treated with only calcium and vitamin D3.

The results showed that those who took vitamin K2 along with their other treatments had improved fusion rates and experienced less back pain. Furthermore, clinical symptoms improved, and there was a marked promotion of bone health within six months after surgery. Notably, the administration of vitamin K2 also helped maintain bone mineral density.

Overall, this research suggests that incorporating vitamin K2 alongside traditional treatments could be beneficial for individuals dealing with back pain related to osteoporosis. It opens the door for more studies on how we might better treat and manage spinal conditions in these patients.

No more bone pain

Most Useful Review

I use this product out of concern for calcium moving from my bones into my blood, which my doctor didn't address. After consulting a vitamin specialist, I started MK-7 and within two days, I had no more bone pain! It has made a tremendous difference in how I feel. I will continue taking this supplement as it has given me my life back.

Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4.

Most Relevant Research

We investigated how vitamin K2 (VK2) influences the growth of cancer cells, particularly focusing on hepatocellular carcinoma (HCC). Our study centered on the interaction between VK2 and a protein known as HSD17B4, which is known to promote cancer cell proliferation. Previous research had shown that VK2 can bind to this protein, but we aimed to uncover the specific mechanisms behind its potential anti-cancer effects.

Through our experiments, we observed that VK2 can inhibit the growth of HCC cells by binding directly to HSD17B4. Interestingly, VK2 did not alter the expression levels of HSD17B4, which suggests that its impact on cell growth is due to other mechanisms. Specifically, we found that VK2 impedes the activation of important signaling pathways, including AKT and MEK/ERK, which play a critical role in cancer cell proliferation. As a result, this inhibition leads to decreased activity of another protein, STAT3, associated with cancer growth.

Moreover, VK2 demonstrated the ability to suppress the growth of transplanted tumors that were influenced by HSD17B4. These findings not only shed light on VK2's mechanism of action, but they also offer promising insights into its potential role in preventing or treating HCC in future applications.

8.8

Promotes health overall

Most Useful Review

I take MK-7 daily to prevent various health issues, including supporting bone density and fighting cancer. I learned about its benefits on the Dr. Oz show, and it has become an essential part of my routine. I appreciate the many advantages it offers to my overall well-being.