Last update
4/6/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 5 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin K₂ (as MK-7 [Menaquinone-7])
90 mcg
†
Top Medical Research Studies
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
Most Useful Reviews
7.5
Enhanced absorption
4 people found this helpful
Perfect! I take it alongside vitamin D3, which is vital for absorption. Initially prescribed by my endocrinologist, after reviewing options, I found Jarrow’s K2 the most convenient and cost-effective. The small capsules are easy to swallow, and I will be ordering them regularly.
Read More
7.5
Effective support
I took it during pregnancy and ordered it for a friend who is also pregnant. High doses of Vitamin D should be taken with K2 and magnesium. I use this brand on the recommendation of a nutritionist from my course.
Read More
7.5
Prevents calcification
3 people found this helpful
Excellent product with a comfortable dosage of vitamin K2 (MK-7 form). It’s necessary when using high doses of vitamin D to prevent vascular calcification.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
- All Researches
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Enhanced absorption
4 people found this helpful
Perfect! I take it alongside vitamin D3, which is vital for absorption. Initially prescribed by my endocrinologist, after reviewing options, I found Jarrow’s K2 the most convenient and cost-effective. The small capsules are easy to swallow, and I will be ordering them regularly.
Read More
7.5
Effective support
I took it during pregnancy and ordered it for a friend who is also pregnant. High doses of Vitamin D should be taken with K2 and magnesium. I use this brand on the recommendation of a nutritionist from my course.
Read More
7.5
Prevents calcification
3 people found this helpful
Excellent product with a comfortable dosage of vitamin K2 (MK-7 form). It’s necessary when using high doses of vitamin D to prevent vascular calcification.
Read More
7.5
Highly bioavailable
Excellent! This is the most bioavailable form of vitamin K2, and we always order it.
Read More
6
Vascular protection
This bioactive form of Vitamin K2 is well dosed. I used it every other day to complement my high Vitamin D intake and to help prevent vascular calcification after addressing my deficiency over six months.
Read More
Frequently Asked Questions
6
Vascular protection
This bioactive form of Vitamin K2 is well dosed. I used it every other day to complement my high Vitamin D intake and to help prevent vascular calcification after addressing my deficiency over six months.
7.5
Prevents calcification
3 people found this helpful
Excellent product with a comfortable dosage of vitamin K2 (MK-7 form). It’s necessary when using high doses of vitamin D to prevent vascular calcification.
7.5
Highly bioavailable
Excellent! This is the most bioavailable form of vitamin K2, and we always order it.
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
References
- Sikorska M, Chmiel J, Papuga-Szela E, Broniatowska E, Undas A. Apixaban Versus Vitamin K Antagonists in Patients With Antiphospholipid Syndrome: A Cohort Study. J Cardiovasc Pharmacol. 2024;84:36. 10.1097/FJC.0000000000001578
- Asadian N, Aprico A, Chen M, Yuen D, Johnston APR, et al. The therapeutic effect of GAS6 in remyelination is dependent upon Tyro3. Glia. 2024;72:1392. 10.1002/glia.24534
- Cheng C, Yang H, Yang C, Xie J, Wang J, et al. LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis. Arthritis Res Ther. 2024;26:64. 10.1186/s13075-024-03292-y
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