Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin K₂ (as MK-7 [Menaquinone-7])
90 mcg
†
Top Medical Research Studies
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
Most Useful Reviews
9
Essential for D3
1 people found this helpful
Vitamin K2 is essential when high doses of D3 are prescribed to prevent calcification in blood vessels and soft tissues.
Read More
7.5
Improved wellbeing
6 people found this helpful
I purchased this for my husband, who is very proactive about his health. He has various conditions affecting his wellbeing, and neither of us rely on all the prescribed medications due to side effects. This Jarrow product has helped improve his symptoms, much to his doctor’s approval. I manage our supplement orders, and after receiving a great coupon, I included the MK-7 to avoid running out. I highly recommend this product.
Read More
2
Coughing concern
5 people found this helpful
After reading reviews on MK7, I tried Jarrow’s product. However, after just two days, both my son and I developed a low-grade cough. I stopped using it, and the cough quickly resolved, indicating a potential issue with this brand.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
- All Researches
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Essential for D3
1 people found this helpful
Vitamin K2 is essential when high doses of D3 are prescribed to prevent calcification in blood vessels and soft tissues.
Read More
7.5
Improved wellbeing
6 people found this helpful
I purchased this for my husband, who is very proactive about his health. He has various conditions affecting his wellbeing, and neither of us rely on all the prescribed medications due to side effects. This Jarrow product has helped improve his symptoms, much to his doctor’s approval. I manage our supplement orders, and after receiving a great coupon, I included the MK-7 to avoid running out. I highly recommend this product.
Read More
2
Coughing concern
5 people found this helpful
After reading reviews on MK7, I tried Jarrow’s product. However, after just two days, both my son and I developed a low-grade cough. I stopped using it, and the cough quickly resolved, indicating a potential issue with this brand.
Read More
7.5
Enhanced absorption
4 people found this helpful
Perfect! I take it alongside vitamin D3, which is vital for absorption. Initially prescribed by my endocrinologist, after reviewing options, I found Jarrow’s K2 the most convenient and cost-effective. The small capsules are easy to swallow, and I will be ordering them regularly.
Read More
7.5
Supports autoimmune health
1 people found this helpful
Taking vitamin D with K2 supports my bone health and autoimmune disorders such as psoriasis and autoimmune thyroiditis. This combination works effectively for me.
Read More
Frequently Asked Questions
7.5
Improved wellbeing
6 people found this helpful
I purchased this for my husband, who is very proactive about his health. He has various conditions affecting his wellbeing, and neither of us rely on all the prescribed medications due to side effects. This Jarrow product has helped improve his symptoms, much to his doctor’s approval. I manage our supplement orders, and after receiving a great coupon, I included the MK-7 to avoid running out. I highly recommend this product.
2
Coughing concern
5 people found this helpful
After reading reviews on MK7, I tried Jarrow’s product. However, after just two days, both my son and I developed a low-grade cough. I stopped using it, and the cough quickly resolved, indicating a potential issue with this brand.
7.5
Supports autoimmune health
1 people found this helpful
Taking vitamin D with K2 supports my bone health and autoimmune disorders such as psoriasis and autoimmune thyroiditis. This combination works effectively for me.
6
Vascular protection
This bioactive form of Vitamin K2 is well dosed. I used it every other day to complement my high Vitamin D intake and to help prevent vascular calcification after addressing my deficiency over six months.
7.5
Prevents calcification
3 people found this helpful
Excellent product with a comfortable dosage of vitamin K2 (MK-7 form). It’s necessary when using high doses of vitamin D to prevent vascular calcification.
9
Essential for D3
1 people found this helpful
Vitamin K2 is essential when high doses of D3 are prescribed to prevent calcification in blood vessels and soft tissues.
7.5
Preventive measures
This is my go-to supplement as taking higher doses of Vitamin D3 requires Vitamin K2 to avoid calcifications in blood vessels and kidneys. For each 5000 IU of Vitamin D3, I ensure I take 90-100 mcg of K2 with a fatty meal.
7.5
Osteoporosis prevention
I previously took vitamin D3 alone but stopped to add vitamin K2. My doctor recommends it to alleviate encephalopathy symptoms. The small capsules are easy to swallow, and this MK7 form of K2 is the most absorbable. I recommend it for those over 50 to prevent osteoporosis and vascular issues.
7.5
Highly bioavailable
Excellent! This is the most bioavailable form of vitamin K2, and we always order it.
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
References
- Sikorska M, Chmiel J, Papuga-Szela E, Broniatowska E, Undas A. Apixaban Versus Vitamin K Antagonists in Patients With Antiphospholipid Syndrome: A Cohort Study. J Cardiovasc Pharmacol. 2024;84:36. doi:10.1097/FJC.0000000000001578
- Asadian N, Aprico A, Chen M, Yuen D, Johnston APR, et al. The therapeutic effect of GAS6 in remyelination is dependent upon Tyro3. Glia. 2024;72:1392. doi:10.1002/glia.24534
- Cheng C, Yang H, Yang C, Xie J, Wang J, et al. LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis. Arthritis Res Ther. 2024;26:64. doi:10.1186/s13075-024-03292-y
