5/21/2025
Last update
5/21/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 64 Reviews
8.1
Supplement Facts
Serving Size: 1 gummy, 1 gummy, 2 gummies
Amount Per Serving
%DV
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
Most Useful Reviews
9
Eased bedtime struggles
23 people found this helpful
I was most excited about this product! My daughter used to tire me greatly at bedtime, but after giving her two pills, she settled down and fell asleep in less than half an hour.
Read More
9
Facilitated bedtime
15 people found this helpful
This product has saved my life! My 3-year-old twins now ask to go to bed and settle down within 30 minutes, sometimes even before I finish reading to them.
Read More
9
Improved morning mood
6 people found this helpful
My 4-year-old boy used to take hours to fall asleep and would wake up crying. Now, with melatonin, he falls asleep within half an hour and wakes up happy in the morning.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 64 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eased bedtime struggles
23 people found this helpful
I was most excited about this product! My daughter used to tire me greatly at bedtime, but after giving her two pills, she settled down and fell asleep in less than half an hour.
Read More
9
Facilitated bedtime
15 people found this helpful
This product has saved my life! My 3-year-old twins now ask to go to bed and settle down within 30 minutes, sometimes even before I finish reading to them.
Read More
9
Improved morning mood
6 people found this helpful
My 4-year-old boy used to take hours to fall asleep and would wake up crying. Now, with melatonin, he falls asleep within half an hour and wakes up happy in the morning.
Read More
9
Enhanced sleep duration
6 people found this helpful
I give my children one gummy when needed, such as before travel or school. It helps them enjoy a peaceful sleep for at least 10 hours.
Read More
9
Natural sedative
4 people found this helpful
A natural sedative for hyperactive children who sleep little. I can’t do without it; it regulates their sleep effectively and is safe to use. I recommend it for all mothers dealing with similar issues.
Read More
Frequently Asked Questions
9
Effective sleep aid
4 people found this helpful
Excellent! I extensively researched this before giving it to my daughter. It’s wonderful and poses no harm. After just 10 minutes of taking it, she enters a deep, long sleep. I'm so pleased with the results!
9
Easier bedtime
2 people found this helpful
I have 3-year-old twins who struggled with sleep apnea and took hours to get to sleep. Since giving them these gummies, they now ask to go to bed and are snoring within 30 minutes, often before the end of the bedtime story.
9
Sleep disorder relief
1 people found this helpful
My 3-year-old has a sleep disorder, and it typically took two hours for him to fall asleep. However, after taking one of these gummies, he falls asleep right on time, 30 minutes after taking it. He now wakes up refreshed and happy. The sleep aid my paediatric neurologist recommended is similar, so it’s safe for my son to have daily.
9
Improved morning mood
6 people found this helpful
My 4-year-old boy used to take hours to fall asleep and would wake up crying. Now, with melatonin, he falls asleep within half an hour and wakes up happy in the morning.
9
Facilitated bedtime
15 people found this helpful
This product has saved my life! My 3-year-old twins now ask to go to bed and settle down within 30 minutes, sometimes even before I finish reading to them.
9
Improved sleep quality
2 people found this helpful
I wish I had found this product earlier. My son has struggled with sleep apnea for two years, resulting in dark circles under his eyes. This product is a lifesaver; we bought it once and it works wonders. Both kids and adults benefit—my son claims he sleeps better and feels more energised the next day, no longer tossing and turning for hours. I've recommended it to friends, who also gave positive feedback. This is my second purchase, and I ordered three more bottles.
9
Promotes independence
1 people found this helpful
My 4-year-old used to sleep late, waking multiple times each night and reluctant to sleep alone. After just two days of using these gummies, they worked within half an hour! Now, following dinner and a gummy, he’s asleep quickly. I wish I had discovered these sooner; he sleeps through the night and is much happier! My 8-year-old has them too, and his sleep quality and behaviour at school have improved significantly. Amazing product!
9
Quick sleep aid
2 people found this helpful
This supplement is incredible; my son used to struggle with sleep apnea, sometimes staying awake until 3 am. After taking it, he falls asleep within ten minutes.
9
Relaxing for children
2 people found this helpful
This excellent product helps my 3-year-old daughter with sleep apnea when she refuses to sleep or is restless. It relaxes her, allowing for deep sleep. I have also taken it when feeling tired, and it greatly aids relaxation and sleep.
9
Calming effects
1 people found this helpful
This miracle drug has worked wonders for my 3-year-old. He used to fight sleep for two hours due to sleep apnea and would wake during the night. Since starting this regimen, he falls asleep promptly and stays asleep, allowing his nervous system to recover through proper sleep.
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. 10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. 10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. 10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. 10.1007/s11325-022-02574-6
