'
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Likely Ineffective
Based on 106 Reviews
4.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Biotin
10,000 mcg
33,333%
Calcium (as Dibasic Calcium Phosphate)
66 mg
5%

Top Medical Research Studies

7
Biotin's potential in acne treatment
Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea.
Relevant acne treatment discussion
We explored the effectiveness of biotin as a treatment for acne, focusing on its potential benefits for those experiencing skin issues linked to biotin deficiency. Biotin is a vitamin that, when levels are low, can contribute to hair loss and skin disorders like seborrheic dermatitis.

In our overview, we noted that while biotin may help improve hair loss, its impact on acne treatment shows promise primarily when combined with other therapies, particularly topical retinoids. These treatments address not just acne but also flaking and irritation commonly associated with skin conditions.

Overall, we found that biotin's role in managing acne is intriguing, especially given its excellent tolerability and safety, even at high doses. However, we emphasize that biotin should be taken under medical supervision following a proper diagnosis.
Read More
8
Biotin aids isotretinoin effects
Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
Combines biotin with isotretinoin
We evaluated the effects of biotin on acne treatment by studying two groups of patients undergoing isotretinoin therapy. Our research involved 60 participants, with each group consisting of 30 individuals. Both groups received isotretinoin, but only one group incorporated a daily biotin supplement.

Throughout the study, we measured changes in skin and hair using various methods, including a digital dermoscope and a specialized device assessing skin hydration and sebum levels. We found that the group taking biotin experienced significant improvements: the rate of hair in the anagen (growth) phase increased, while hair in the telogen (resting) phase decreased. Meanwhile, those who just took isotretinoin alone faced a notable drop in skin hydration.

The results suggest that adding biotin can effectively help maintain skin health and reduce some common side effects associated with isotretinoin. This indicates that biotin may have a protective role against the adverse effects typically seen in patients undergoing acne treatments.
Read More
8
Biotin's potential in acne treatment
Novel combination for the treatment of acne differentiated based on gender: a new step towards personalized treatment.
Effect of biotin on acne unclear
We explored the effectiveness of a targeted skin care routine specifically designed for both men and women struggling with mild to moderate acne. This routine included a unique oral supplement that featured biotin, among other ingredients, and a topical cream. What stood out in this study was the focus on gender-specific formulations—men received added beta sitosterol and Boswellia serrata, while women had myo-inositol and folic acid in their supplements.

During the trial, male and female participants were treated in a double-blinded setup, allowing us to assess their progress via the Global Acne Grading System at two different intervals. By week 12, we noticed that the majority of participants demonstrated a significant improvement in their acne severity. Interestingly, those who took the oral supplement, which included biotin, exhibited even more remarkable results.

Our findings indicate that incorporating biotin, along with other active ingredients, may contribute positively to improving acne conditions. However, we must note that while biotin appears beneficial, it was part of a broader formulation, making it challenging to pinpoint its specific impact on acne outcomes alone.
Read More

Most Useful Reviews

5
Avoids acne issues
Do not eat it. Biotin can activate fat metabolism, which may stimulate sebaceous glands, leading to purulent acne on my chin. I'm stressed and considering Roacutan treatment. If consuming a hamburger, please increase dosage slowly. I have not been comfortable with mirrors lately.
Read More
2.5
Acne side effects
Biotin is beneficial but has side effects. Though it can strengthen hair and nails, it also causes acne, among other issues.
Read More
9.5
Cleared red spots
Excellent! I chose high-dose biotin for the best results. After two weeks, the red spots on my face have disappeared, possibly from acne. This supplement has also benefited my hair, nails, and skin, and I recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
8
Biotin's role in acne therapy
Probiotic supplement combined with topical therapy in the treatment of mild to moderate acne: results from an Italian single centre interventional study.
Limited relevance due to study design
We explored the potential of combining an oral biotin supplement with a topical gel in addressing mild to moderate acne. Our research focused on understanding whether this innovative treatment approach could provide better results than traditional therapies, which often come with side effects.

In our study, we treated participants with a specially formulated supplement containing biotin and three strains of lactic ferments, alongside a topical gel that included azelaic acid, hydroxypinacolone retinoate, and α-hydroxy acids. After 60 days of treatment, we observed notable improvements among the patients.

While we did not solely evaluate the isolated effects of biotin, our findings indicate that combining it with topical treatments may hold promise for managing acne symptoms. However, we must acknowledge that more focused research is necessary to pinpoint the direct impact of biotin itself on acne specifically.
Read More
8
Biotin aids isotretinoin effects
Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
Combines biotin with isotretinoin
We evaluated the effects of biotin on acne treatment by studying two groups of patients undergoing isotretinoin therapy. Our research involved 60 participants, with each group consisting of 30 individuals. Both groups received isotretinoin, but only one group incorporated a daily biotin supplement.

Throughout the study, we measured changes in skin and hair using various methods, including a digital dermoscope and a specialized device assessing skin hydration and sebum levels. We found that the group taking biotin experienced significant improvements: the rate of hair in the anagen (growth) phase increased, while hair in the telogen (resting) phase decreased. Meanwhile, those who just took isotretinoin alone faced a notable drop in skin hydration.

The results suggest that adding biotin can effectively help maintain skin health and reduce some common side effects associated with isotretinoin. This indicates that biotin may have a protective role against the adverse effects typically seen in patients undergoing acne treatments.
Read More
8
Combination therapy improves PCOS symptoms
Efficacy of combination therapy of inositols, antioxidants and vitamins in obese and non-obese women with polycystic ovary syndrome: an observational study.
Biotin's isolated effect unclear
In our exploration of the effects of a combination therapy involving biotin on acne, we found ourselves focusing on women diagnosed with polycystic ovary syndrome (PCOS). The study highlighted a treatment that included not just biotin but also insulin sensitizers and antioxidants, aiming to improve various symptoms of PCOS, including skin issues like acne.

We observed that after 12 weeks of supplementation, notable improvements were reported in conditions such as acne and menstrual irregularities among both obese and lean women with PCOS. However, it’s important to clarify that while biotin was part of the combined therapy, the study did not isolate its specific impact on acne, making it difficult to definitively conclude how effective biotin is when used alone for this skin concern.

Therefore, while the combination approach showed promise overall, the role of biotin in directly alleviating acne remains inconclusive based on this study alone. We suggest further investigation could clarify its specific effects.
Read More
8
Biotin's potential in acne treatment
Novel combination for the treatment of acne differentiated based on gender: a new step towards personalized treatment.
Effect of biotin on acne unclear
We explored the effectiveness of a targeted skin care routine specifically designed for both men and women struggling with mild to moderate acne. This routine included a unique oral supplement that featured biotin, among other ingredients, and a topical cream. What stood out in this study was the focus on gender-specific formulations—men received added beta sitosterol and Boswellia serrata, while women had myo-inositol and folic acid in their supplements.

During the trial, male and female participants were treated in a double-blinded setup, allowing us to assess their progress via the Global Acne Grading System at two different intervals. By week 12, we noticed that the majority of participants demonstrated a significant improvement in their acne severity. Interestingly, those who took the oral supplement, which included biotin, exhibited even more remarkable results.

Our findings indicate that incorporating biotin, along with other active ingredients, may contribute positively to improving acne conditions. However, we must note that while biotin appears beneficial, it was part of a broader formulation, making it challenging to pinpoint its specific impact on acne outcomes alone.
Read More
7
Biotin's potential in acne treatment
Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea.
Relevant acne treatment discussion
We explored the effectiveness of biotin as a treatment for acne, focusing on its potential benefits for those experiencing skin issues linked to biotin deficiency. Biotin is a vitamin that, when levels are low, can contribute to hair loss and skin disorders like seborrheic dermatitis.

In our overview, we noted that while biotin may help improve hair loss, its impact on acne treatment shows promise primarily when combined with other therapies, particularly topical retinoids. These treatments address not just acne but also flaking and irritation commonly associated with skin conditions.

Overall, we found that biotin's role in managing acne is intriguing, especially given its excellent tolerability and safety, even at high doses. However, we emphasize that biotin should be taken under medical supervision following a proper diagnosis.
Read More

User Reviews

USERS' SCORE
Likely Ineffective
Based on 106 Reviews
4.6
9.5
Cleared red spots
Excellent! I chose high-dose biotin for the best results. After two weeks, the red spots on my face have disappeared, possibly from acne. This supplement has also benefited my hair, nails, and skin, and I recommend it!
9.5
Severe side effects
One star. This product caused severe side effects, including acne and itching, and I have been suffering for a month. I’m uncertain if it’s due to atopy.
9.5
Hair impact noted
I began taking biotin for my hair but noticed a tremendous effect on my acne. Initially plagued with acne, I found this was effective after two weeks of use. The results for my hair were also positive, and I recommend it for those with rough skin.
9.5
Acne solution
Biotin is essential for hair, skin, nails, and can help with acne-prone skin. I noticed a reduction in redness from allergies without using steroids. My nails are less brittle and appear stronger. If you’re dealing with thinning hair or want to prevent it, I recommend taking biotin.
9.5
Improved acne
My acne has improved noticeably. I discovered through a nutritional test that I was low on biotin. It's crucial that my intestines are healthy to absorb it properly. Once I began taking it with probiotics, the stubborn acne on my chin became much lighter, and my skin improved overall. I plan to keep taking it.
Read More
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