Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
USERS' SCORE
Good
Based on 36 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Biotin
10,000 mcg
33,333%
Calcium (as Dibasic Calcium Phosphate)
66 mg
5%
Top Medical Research Studies
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More
Most Useful Reviews
9
Improved skin condition
84 people found this helpful
Biotin helped with my severe hair loss and also improved my skin condition. It’s beneficial for hair, skin, and nails, assisting with problems like eczema. I’ve noticed better overall wellbeing and energy.
Read More
9
Eczema improvement
21 people found this helpful
My dog had skin issues, and after using biotin, his eczema improved significantly. I stopped giving it for a while, but the eczema returned. Biotin is now a staple in his routine.
Read More
9
Eczema resolved
16 people found this helpful
I purchased biotin for my daughter’s eczema on her neck. After 10 days of using biotin and zinc oxide ointment without steroids, she is now completely better. The capsules are small and easy for children to take.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
- All Researches
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More
8
We examined a rare condition called holocarboxylase synthetase (HLCS) deficiency, which affects biotin metabolism in patients. Our study focused on five patients diagnosed between 2015 and 2024.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Read More
7
We explored how biotin treatment affects patients with biotinidase deficiency, focusing on their clinical features, which include skin conditions like eczema. In our study, six patients ranging from only a few months old to 14 years displayed a variety of neurological and dermatological symptoms.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Read More
User Reviews
USERS' SCORE
Good
Based on 36 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved skin condition
84 people found this helpful
Biotin helped with my severe hair loss and also improved my skin condition. It’s beneficial for hair, skin, and nails, assisting with problems like eczema. I’ve noticed better overall wellbeing and energy.
Read More
9
Eczema improvement
21 people found this helpful
My dog had skin issues, and after using biotin, his eczema improved significantly. I stopped giving it for a while, but the eczema returned. Biotin is now a staple in his routine.
Read More
9
Eczema resolved
16 people found this helpful
I purchased biotin for my daughter’s eczema on her neck. After 10 days of using biotin and zinc oxide ointment without steroids, she is now completely better. The capsules are small and easy for children to take.
Read More
10
Complete recovery
7 people found this helpful
I struggled with housewife's eczema for years, trying numerous treatments without success. Biotin eventually solved the issue completely, and I continue to take it to prevent recurrence.
Read More
9
Eczema decreased
7 people found this helpful
After developing hand eczema that was difficult to heal, biotin was suggested to me. After starting biotin, my eczema diminished within a week and completely disappeared in about two months.
Read More
Frequently Asked Questions
9
Eczema decreased
7 people found this helpful
After developing hand eczema that was difficult to heal, biotin was suggested to me. After starting biotin, my eczema diminished within a week and completely disappeared in about two months.
9
Eczema treatment success
1 people found this helpful
I'm continuing with biotin as my eczema was significantly reduced within a month of use. My hair and nails also seem to benefit, which my co-workers have noticed. I plan to keep using it.
7.5
Clean skin achieved
3 people found this helpful
I have chronic eczema and severe hair loss. After taking these tablets for four months alongside Omega-3, my skin cleared up, though hair loss persists. My hair is now silkier. This has worked for me where hormonal treatments fell short.
9
Eczema resolved
16 people found this helpful
I purchased biotin for my daughter’s eczema on her neck. After 10 days of using biotin and zinc oxide ointment without steroids, she is now completely better. The capsules are small and easy for children to take.
9
Joint symptom relief
6 people found this helpful
I was troubled by severe eczema and joint cracks, but after a month of biotin therapy, my rough hands have improved dramatically. Eczema has subsided, and my wound healing seems accelerated. I plan to keep using biotin to maintain my progress.
10
Complete recovery
7 people found this helpful
I struggled with housewife's eczema for years, trying numerous treatments without success. Biotin eventually solved the issue completely, and I continue to take it to prevent recurrence.
0
No improvement noted
Unfortunately, I saw no expected results from taking biotin. My hair condition hasn't improved and my eczema has worsened.
7.5
Reduced stress
29 people found this helpful
After 10 years of using antihistamines and steroids for hand eczema, I tried biotin with Miyarisan. Now, my eczema has improved significantly; it no longer swells or causes distress, making my life more manageable.
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
7
We explored how biotin treatment affects patients with biotinidase deficiency, focusing on their clinical features, which include skin conditions like eczema. In our study, six patients ranging from only a few months old to 14 years displayed a variety of neurological and dermatological symptoms.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
8
We examined a rare condition called holocarboxylase synthetase (HLCS) deficiency, which affects biotin metabolism in patients. Our study focused on five patients diagnosed between 2015 and 2024.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
References
- Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
- Hagiwara SI, Kubota M, Nambu R, Kagimoto S. Screening of carnitine and biotin deficiencies on tandem mass spectrometry. Pediatr Int. 2017;59:458. doi:10.1111/ped.13167
- Yang YL, Yamaguchi S, Tagami Y, Zhang YH, Xiong H, et al. [Diagnosis and treatment of biotinidase deficiency-clinical study of six patients]. Zhonghua Er Ke Za Zhi. 2003;41:249.
- Kimura M, Fukui T, Tagami Y, Fujiwaki T, Yokoyama M, et al. Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation. J Inherit Metab Dis. 2003;26:715.
- Ting SL, Yakob Y, Sani HA, Rethanavelu K, Ngu LH. Holocarboxylase Synthetase Deficiency: Clinical, Biochemical and Molecular Findings in Five Malaysian Patients Including a Newborn Presenting as Collodion Baby. JIMD Rep. 2025;66:e70006. doi:10.1002/jmd2.70006
