' 
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Melatonin
1 mg
*
Lemon Balm Extract(Melissa officinalis) (aerial parts)
1 mg
*
The product is found useful for the following medical conditions
Insomnia details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.2
USERS' SCORE
Good
Based on 10 Reviews
8.7
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Most Relevant Research
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
9.5
Effective for children
Most Useful Review
We tried the children's melatonin for our four-year-old, and the results are remarkable. The strawberry flavour is appealing to her. It significantly improves her sleep; she now falls asleep faster and enjoys sounder sleep, alleviating our previous insomnia struggles. We highly recommend it to parents!
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Effective sleep aid
Most Useful Review
Natrol Rapid Melatonin is an effective sleep aid for children, with a pleasant strawberry flavour. The 1 mg dose helps children to fall asleep easily and sleep soundly, without morning fatigue. It contains no artificial additives, ensuring safety for regular use.
Knee Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Improved knee health
Most Useful Review
Amazing! The product quality is fantastic, with fresh ingredients suitable for those aged 18 and above. The composition is impeccable. I have experienced significant improvement in my body, particularly with regards to knee pain. The effect is remarkable, aiding my diet and promoting knee health without any issues with packaging.
Anxiety details
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Melatonin reduces anxiety from glyphosate
Melatonin attenuates affective disorders and cognitive deficits induced by perinatal exposure to a glyphosate-based herbicide via antioxidant pathway in adult male and female rats.
Most Relevant Research
Our research examined the effects of melatonin on anxiety and memory problems caused by exposure to glyphosate-based herbicides (GBH). We started with pregnant Wistar rats that were subjected to GBH during gestation and lactation. After weaning, the offspring were treated with melatonin to see if it could help mitigate the negative effects they experienced due to their early exposure.
We observed that exposure to GBH led to increased anxiety and depression-like behaviors in the rats. Additionally, it appeared to impair their memory function. In looking at oxidative stress markers in the brain regions associated with emotion and cognition, we found indications of increased stress—especially pronounced in the female offspring.
However, the inclusion of melatonin significantly reduced these anxiety levels and improved cognitive deficits. Interestingly, the benefits were notably greater in female rats compared to males, suggesting a potential sex-dependent response to melatonin treatment.
We observed that exposure to GBH led to increased anxiety and depression-like behaviors in the rats. Additionally, it appeared to impair their memory function. In looking at oxidative stress markers in the brain regions associated with emotion and cognition, we found indications of increased stress—especially pronounced in the female offspring.
However, the inclusion of melatonin significantly reduced these anxiety levels and improved cognitive deficits. Interestingly, the benefits were notably greater in female rats compared to males, suggesting a potential sex-dependent response to melatonin treatment.
7.5
Child's anxiety reduction
Most Useful Review
Nighttime Anxiety. My 9-year-old child has experienced significant improvements in sleeping through the night and a reduced level of anxiety before bed since taking these. She occasionally complains of dizziness, particularly if she doesn't settle down, but overall, we’ll continue using these.
Sleep Apnea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 13 Reviews
8.2
9.5
Improved bedtime routine
Most Useful Review
This has transformed our evening routine. After four years of struggles with bedtimes, my son now asks to go to bed and sleeps well after just a week of use. This brand is well-supported, and I followed my GP’s advice in giving it to my child.
