5/12/2025
Last update
5/12/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8
Supplement Facts
Serving Size: 2 Gummies
Amount Per Serving
%DV
Calories
20
Total Carbohydrate
4 g
1%*
Total Sugars
3 g
**
Includes 3 g Added Sugars
6%*
Sodium
5 mg
<1%
Melatonin
10 mg
**
Top Medical Research Studies
7
We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Read More
8
Melatonin may reduce postoperative nausea
In a recent clinical trial involving 99 patients undergoing laminectomy, we explored the effectiveness of melatonin on postoperative nausea. Participants were divided into three groups: one received melatonin, another had gabapentin, and the third was given a starch placebo. The goal was to compare how each treatment affected both pain and anxiety following surgery.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Read More
Most Useful Reviews
9
Nausea-free experience
Occasionally, I try a sleeping form, and I enjoy it. I sleep comfortably, and when I wake, I don’t feel nauseous. It doesn’t cause nausea, and it still has a pleasant sweetness.
Read More
2
Persistent nausea
1 people found this helpful
Nausea all day... Sometimes, I awaken in the middle of the night and cannot sleep for about two hours. When that occurs, I tear off about half and consume it. After doing so, I can drift off to sleep immediately; however, nausea and dizziness persist from the following morning until night. It appears that not many others experience such symptoms, but they do not happen every time—just sometimes. Waking up in the middle of the night is challenging, but I will continue this practice from now on.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Melatonin may reduce postoperative nausea
In a recent clinical trial involving 99 patients undergoing laminectomy, we explored the effectiveness of melatonin on postoperative nausea. Participants were divided into three groups: one received melatonin, another had gabapentin, and the third was given a starch placebo. The goal was to compare how each treatment affected both pain and anxiety following surgery.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Read More
7
We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Nausea-free experience
Occasionally, I try a sleeping form, and I enjoy it. I sleep comfortably, and when I wake, I don’t feel nauseous. It doesn’t cause nausea, and it still has a pleasant sweetness.
Read More
2
Persistent nausea
1 people found this helpful
Nausea all day... Sometimes, I awaken in the middle of the night and cannot sleep for about two hours. When that occurs, I tear off about half and consume it. After doing so, I can drift off to sleep immediately; however, nausea and dizziness persist from the following morning until night. It appears that not many others experience such symptoms, but they do not happen every time—just sometimes. Waking up in the middle of the night is challenging, but I will continue this practice from now on.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Jouybar R, Kazemifar S, Asmarian N, Karami A, Khademi S. Comparison of the effect of melatonin, dexmedetomidine, and gabapentin on reduction of postoperative pain and anxiety following laminectomy: a randomized clinical trial. BMC Anesthesiol. 2022;22:318. 10.1186/s12871-022-01851-x
- Söderquist F, Janson ET, Rasmusson AJ, Ali A, Stridsberg M, et al. Melatonin Immunoreactivity in Malignant Small Intestinal Neuroendocrine Tumours. PLoS One. 2016;11:e0164354. 10.1371/journal.pone.0164354
