Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Melatonin
10 mg
*

The product is found useful for the following medical conditions

Anxiety details

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7
USERS' SCORE
Good
Based on 9 Reviews
8.8
9
Melatonin reduces pediatric anxiety, pain
The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
Most Relevant Research
We focused on the effects of oral melatonin on anxiety and pain in children during the stressful process of venipuncture. In a double-blind, randomized controlled trial, we found that administering 0.5 mg/kg of melatonin 30 minutes before the procedure significantly reduced both pain and anxiety levels compared to a placebo.

The results showed that only 18.8% of the kids receiving melatonin reported pain, while 78.2% in the placebo group did. Furthermore, anxiety affected 44.6% of the melatonin group compared to 94.1% of those in the control group.

While melatonin appeared to improve experiences during venipuncture, its impact on the success rate was not statistically significant.
9.5
Anti-stress effect
Most Useful Review
Melatonin's benefits include stimulating the immune system by activating the thymus gland and the thyroid gland. It reduces anxiety and enhances the emotional state. Under stress, it lowers adrenaline and other hormones, demonstrating an anti-stress effect.

Pelvic Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.8
9.5
Improved sleep quality
Most Useful Review
Never slept better! I have suffered from severe joint and hip pain for many years, making it difficult to fall asleep. The pain kept me awake and was all I could focus on. But since I began taking Natrol Melatonin 10mg twenty minutes before bed, I fall asleep almost instantly. If I wake during the night, I can easily drift back off. Now, I can sleep without lying awake thinking about my hip pain. I absolutely love this product! It has changed my life.

Sleep Apnea details

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 88 Reviews
8.8
9.5
Melatonin improves sleep apnea outcomes
Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial.
Most Relevant Research
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.

The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.

Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
8.8
Effective sleep aid
Most Useful Review
This product helps me sleep effectively.

Adhd details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 15 Reviews
8.7
9.5
Better sleep
Most Useful Review
The best thing since sliced bread! This stuff is a lifesaver; my ADHD grandson, who previously struggled to fall asleep, has been sleeping much better since he started taking it. Thank you!

Brain Tumor details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Improved sleep quality
Most Useful Review
Works perfectly for me. Exactly what I needed. The flavour is decent and does not taste of chemicals. I take the tablet, read my book for 15-20 minutes, and then enjoy an amazing night’s sleep. I am not groggy in the morning. I had to train my body for a new sleeping schedule in a new location. These tablets were instrumental in transforming my restless nights and training my brain to feel sleepy in that environment. I would highly recommend.

Menopause details

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Melatonin aids perimenopausal relief
Influence of Melatonin Treatment on Emotion, Sleep, and Life Quality in Perimenopausal Women: A Clinical Study.
Most Relevant Research
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.

After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.

Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
9.5
Improved sleep quality
Most Useful Review
These are a lifesaver. After experiencing menopause, I struggled with sleeping through the night, waking frequently and having bouts of insomnia. Since I started taking these 10mg tablets from Natrol, I can finally sleep well.

Cardiovascular Disease details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Effective for insomnia
Most Useful Review
This wonderful product enhances sleep quality, aids in falling asleep, and is effective in treating insomnia.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
2
Melatonin ineffective for CFS symptoms
Therapy of circadian rhythm disorders in chronic fatigue syndrome: no symptomatic improvement with melatonin or phototherapy.
Most Relevant Research
We evaluated whether melatonin and bright-light phototherapy could help alleviate symptoms of chronic fatigue syndrome (CFS). In a controlled study with thirty participants, we assessed the effectiveness of these treatments by measuring various symptoms over several weeks.

Unfortunately, we found that neither melatonin nor phototherapy led to significant improvements in the patients’ symptoms or overall health. Our findings suggest that these treatments shouldn't be promoted for CFS unless proven beneficial.
9.5
Miracle sleep aid
Most Useful Review
I'm eager to praise this drug! I suffered from long-term insomnia; my doctor prescribed sleeping pills, but they became addictive and less effective. I decided to try melatonin without much hope, but it came as a miracle! After the very first dose, I was able to fall asleep quickly and could do so again if I woke in the night. I wake up feeling refreshed without the fatigue I experienced from prescribed medications. This drug is now a staple for me, and I’ve had no unpleasant side effects after over six months. I’d certainly recommend it to anyone facing sleep issues. Good night and sound sleep to all!

Chronic Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
9.5
Good for sleep
Most Useful Review
With multiple joint replacements and chronic osteoarthritis, my sleep was severely affected. However, this melatonin supplement enabled me to fall asleep and stay asleep.

Cancer details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9.5
Improved survival rate
Most Useful Review
The survival rate for those with mammary cancer who take melatonin daily is higher. I have been taking it daily for two years now. I have stage 4 cancer and am still alive.

Depression details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.3
8.8
Improves sleep quality
Most Useful Review
Melatonin is a hormone with several health benefits: it improves sleep quality, has antioxidant properties, alleviates depression, and reduces stomach acidity.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 6 Reviews
8.2
8
Melatonin improves MS-related symptoms
12-week melatonin intake attenuates cardiac autonomic dysfunction and oxidative stress in multiple sclerosis patients: a randomized controlled trial.
Most Relevant Research
We explored the impact of melatonin on patients with multiple sclerosis (MS), aiming to improve heart function and sleep. In a randomized controlled trial, participants received either melatonin or a placebo for 12 weeks.

We observed significant improvements in heart rate variability and markers of oxidative stress, suggesting that melatonin could enhance heart health and lower stress in MS patients. Additionally, sleep quality and quantity also improved with melatonin use.

This study indicates that melatonin might be a beneficial treatment option for managing cardiac issues and sleep disturbances in MS.
9.5
Favoured melatonin
Most Useful Review
This one is now my favourite melatonin. I ordered 5mg before, which also worked well, but this is the best! It melts in your mouth in under a minute and works in around five minutes. With this melatonin, I sleep all night and feel fresh in the morning. I will definitely order it again.

Dizziness details

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.8
7
Melatonin's impact on dizziness
Addressing Sleep Disorders in Psychiatry: Comparing the Use of Melatonin, Trazodone, and Doxepin.
Most Relevant Research
We assessed how melatonin affects dizziness in patients dealing with sleep disturbances tied to psychiatric conditions. In a study with 175 participants, we found that melatonin was slightly less effective than trazodone and doxepin in improving overall sleep quality. However, it stood out for having a low incidence of adverse effects. Specifically, the rates of dizziness associated with melatonin use were measured, showing a relatively low occurrence.

While it did not provide the most substantial improvement in sleep quality, melatonin showed promise in enhancing tolerability among users. Only 10% of participants reported dizziness, which indicates that melatonin might be a safer option for those worried about side effects from more potent medications. By choosing melatonin, patients can potentially find a balance between managing sleep disturbances while minimizing unwanted symptoms like dizziness.

Overall, we observed that for individuals focused on avoiding adverse effects, melatonin serves as a viable alternative within this treatment landscape. Its effectiveness in curbing dizziness contributes to discussions on how best to treat sleep disorders in psychiatric patients without compromising their comfort.
9.5
No dizziness after waking
Most Useful Review
This is the best melatonin available. It doesn’t leave me feeling dizzy after waking, which is a significant plus.

Insomnia details

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.8
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.6
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Most Relevant Research
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.

Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.

Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.

We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
8.8
Helps with insomnia
Most Useful Review
I have been using Melatonin from this manufacturer for several years. I've tried other brands, but this is the best. 3 milligrams is sufficient for me. I take a dose of 10 for my 74-year-old dad, who has heart disease and suffers from insomnia. The doctor recommended melatonin as sleeping pills could be dangerous for his heart.

Back Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.3
1
Limited effectiveness
Most Useful Review
No good. Unfortunately, it doesn't really work for me. Though it helps me fall asleep, I often wake up in the middle of the night and cannot fall back asleep. I wake up feeling really tired.

Headache details

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.3
9.5
Agomelatine relieves hypnic headaches
Case report: Hypnic headache responds to agomelatine-a potential prophylactic treatment option.
Most Relevant Research
We explored how melatonin-based treatments, particularly agomelatine, can affect headaches, focusing on hypnic headaches (HH). This form of headache typically occurs during sleep, disrupting the rest of those affected. A fascinating case of a 58-year-old woman who experienced these nocturnal headaches for three years demonstrated the potential benefits of agomelatine.

After being prescribed 25 mg of agomelatine at bedtime, she reported an impressive 80% reduction in headache frequency and severity within a month. Remarkably, her headaches completely resolved after three months, allowing her to discontinue the medication.

This case highlights the importance of exploring prophylactic treatments aimed at reducing nighttime awakenings caused by HH. Given the significant impact these headaches can have on sleep quality in older populations, treatments that target melatonin receptors could offer a promising avenue for relieving this condition.
9.5
No side effects
Most Useful Review
Its effect is wonderful, and it does not cause any unwanted effects such as headache or nausea. It is very pleasing.
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