Natrol Melatonin Fast Dissolve Tablets

Melatonin aids perimenopausal relief

Based on 10 Researches

Zhang J, Jiang B. Influence of Melatonin Treatment on Emotion, Sleep, and Life Quality in Perimenopausal Women: A Clinical Study. J Healthc Eng. 2023;2023:2198804. doi:10.1155/2023/2198804

We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.

After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.

Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.

Improved sleep quality

Most Useful Review

These are a lifesaver. After experiencing menopause, I struggled with sleeping through the night, waking frequently and having bouts of insomnia. Since I started taking these 10mg tablets from Natrol, I can finally sleep well.

Pelvic Pain details

Improved sleep quality

1 people found this helpful

Never slept better! I have suffered from severe joint and hip pain for many years, making it difficult to fall asleep. The pain kept me awake and was all I could focus on. But since I began taking Natrol Melatonin 10mg twenty minutes before bed, I fall asleep almost instantly. If I wake during the night, I can easily drift back off. Now, I can sleep without lying awake thinking about my hip pain. I absolutely love this product! It has changed my life.

Anxiety details

Melatonin reduces pediatric anxiety, pain

Based on 7 Researches

Rahafard S, Akbari Jokar Z, Hosseini SA, Alaee E. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial. Ann Med Surg (Lond). 2024;86:5811. doi:10.1097/MS9.0000000000002163

We focused on the effects of oral melatonin on anxiety and pain in children during the stressful process of venipuncture. In a double-blind, randomized controlled trial, we found that administering 0.5 mg/kg of melatonin 30 minutes before the procedure significantly reduced both pain and anxiety levels compared to a placebo.

The results showed that only 18.8% of the kids receiving melatonin reported pain, while 78.2% in the placebo group did. Furthermore, anxiety affected 44.6% of the melatonin group compared to 94.1% of those in the control group.

While melatonin appeared to improve experiences during venipuncture, its impact on the success rate was not statistically significant.

Anti-stress effect

Most Useful Review

2 people found this helpful

Melatonin's benefits include stimulating the immune system by activating the thymus gland and the thyroid gland. It reduces anxiety and enhances the emotional state. Under stress, it lowers adrenaline and other hormones, demonstrating an anti-stress effect.

Atrial Septal Defect details

Improved sleep quality

Getting sleep helps atrial septal defect. We use this for our son with autism, and it's the only product that has ever worked. He now gets solid sleep and, although he still wakes during the night, he is able to go back to sleep. Sleep has alleviated his anxiety and sensory issues more than any prescribed medication. I would highly recommend trying it.

Adhd details

Fargason RE, Fobian AD, Hablitz LM, Paul JR, White BA, et al. Correcting delayed circadian phase with bright light therapy predicts improvement in ADHD symptoms: A pilot study. J Psychiatr Res. 2017;91:105. doi:10.1016/j.jpsychires.2017.03.004

Questionable

Based on 7 Researches

Bright light therapy and ADHD

We explored how bright light therapy (BLT) can influence ADHD symptoms, especially in individuals with sleep-wake rhythm delays. The study involved participants undergoing standard treatments along with two weeks of morning BLT, which successfully advanced melatonin release and sleep timing.

As a result, we observed a significant reduction in ADHD symptoms, particularly in hyperactivity and impulsivity. Although the therapy did not change sleep quality significantly, it highlighted potential as a complementary approach to traditional ADHD treatments.

This study marks an encouraging step in finding effective alternatives for managing ADHD symptoms.

Sleep improvement

Most Useful Review

Lifesaver! My 11-year-old son, who has Autism and ADHD, can actually fall asleep now.

Autoimmune Disorder details

Melatonin improves MS-related symptoms

Based on 16 Researches

Jallouli S, Jallouli D, Damak M, Sakka S, Ghroubi S, et al. 12-week melatonin intake attenuates cardiac autonomic dysfunction and oxidative stress in multiple sclerosis patients: a randomized controlled trial. Metab Brain Dis. 2024;40:52. doi:10.1007/s11011-024-01428-2

We explored the impact of melatonin on patients with multiple sclerosis (MS), aiming to improve heart function and sleep. In a randomized controlled trial, participants received either melatonin or a placebo for 12 weeks.

We observed significant improvements in heart rate variability and markers of oxidative stress, suggesting that melatonin could enhance heart health and lower stress in MS patients. Additionally, sleep quality and quantity also improved with melatonin use.

This study indicates that melatonin might be a beneficial treatment option for managing cardiac issues and sleep disturbances in MS.

Favoured melatonin

Most Useful Review

3 people found this helpful

This one is now my favourite melatonin. I ordered 5mg before, which also worked well, but this is the best! It melts in your mouth in under a minute and works in around five minutes. With this melatonin, I sleep all night and feel fresh in the morning. I will definitely order it again.

Cancer details

Improved survival rate

The survival rate for those with mammary cancer who take melatonin daily is higher. I have been taking it daily for two years now. I have stage 4 cancer and am still alive.

Sleep Apnea details

Melatonin improves sleep apnea outcomes

Based on 4 Researches

Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. doi:10.1186/s40780-024-00347-9

We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.

The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.

Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.

Effective sleep aid

Most Useful Review

6 people found this helpful

This product helps me sleep effectively.

Chronic Cough details

With multiple joint replacements and chronic osteoarthritis, my sleep was severely affected. However, this melatonin supplement enabled me to fall asleep and stay asleep.

Back Pain details

Limited effectiveness

No good. Unfortunately, it doesn't really work for me. Though it helps me fall asleep, I often wake up in the middle of the night and cannot fall back asleep. I wake up feeling really tired.

Depression details

Improves sleep quality

Melatonin is a hormone with several health benefits: it improves sleep quality, has antioxidant properties, alleviates depression, and reduces stomach acidity.

Dizziness details

Melatonin's impact on dizziness

Mamoon B, Nawaz A, Khattak MI, Amir F, Akbar A, et al. Addressing Sleep Disorders in Psychiatry: Comparing the Use of Melatonin, Trazodone, and Doxepin. Cureus. 2024;16:e76507. doi:10.7759/cureus.76507

We assessed how melatonin affects dizziness in patients dealing with sleep disturbances tied to psychiatric conditions. In a study with 175 participants, we found that melatonin was slightly less effective than trazodone and doxepin in improving overall sleep quality. However, it stood out for having a low incidence of adverse effects. Specifically, the rates of dizziness associated with melatonin use were measured, showing a relatively low occurrence.

While it did not provide the most substantial improvement in sleep quality, melatonin showed promise in enhancing tolerability among users. Only 10% of participants reported dizziness, which indicates that melatonin might be a safer option for those worried about side effects from more potent medications. By choosing melatonin, patients can potentially find a balance between managing sleep disturbances while minimizing unwanted symptoms like dizziness.

Overall, we observed that for individuals focused on avoiding adverse effects, melatonin serves as a viable alternative within this treatment landscape. Its effectiveness in curbing dizziness contributes to discussions on how best to treat sleep disorders in psychiatric patients without compromising their comfort.

No dizziness after waking

Most Useful Review

This is the best melatonin available. It doesn’t leave me feeling dizzy after waking, which is a significant plus.

Insomnia details

Li X, Chen Y, Shao H, Yan Z, Wang Y, et al. Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation. Int J Biol Macromol. 2025;301:140500. doi:10.1016/j.ijbiomac.2025.140500

Based on 23 Researches

Melatonin delivery enhances sleep

We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.

Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.

Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.

We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.

7.5

Helps with insomnia

Most Useful Review

7 people found this helpful

I have been using Melatonin from this manufacturer for several years. I've tried other brands, but this is the best. 3 milligrams is sufficient for me. I take a dose of 10 for my 74-year-old dad, who has heart disease and suffers from insomnia. The doctor recommended melatonin as sleeping pills could be dangerous for his heart.

Headache details