Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Medium or Average
Based on 5 Reviews
6.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B-6 (as Pyridoxine Hydrochloride)
10 mg
588%
Calcium (as Calcium Carbonate)
60 mg
5%
Melatonin
5 mg
*
Top Medical Research Studies
7
We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Read More
8
Melatonin may reduce postoperative nausea
In a recent clinical trial involving 99 patients undergoing laminectomy, we explored the effectiveness of melatonin on postoperative nausea. Participants were divided into three groups: one received melatonin, another had gabapentin, and the third was given a starch placebo. The goal was to compare how each treatment affected both pain and anxiety following surgery.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Read More
Most Useful Reviews
0
Severe side effects
4 people found this helpful
This product did not suit me at all. I felt heat in my limbs but couldn’t sleep, and the next day I was excessively sleepy. After a few attempts, I experienced headaches, nausea, and a sense of dullness, leading me to discard it.
Read More
9
Natural sleep aid
I've ordered this three times, but it causes nausea unlike other types. After taking half a pill, I can fall asleep naturally as if I'm using sleeping pills.
Read More
0
Considerable dizziness
1 people found this helpful
I experienced severe side effects including dizziness, nausea, and headaches. While it’s recommended on blogs, I suggest buying it with caution due to these adverse effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Melatonin may reduce postoperative nausea
In a recent clinical trial involving 99 patients undergoing laminectomy, we explored the effectiveness of melatonin on postoperative nausea. Participants were divided into three groups: one received melatonin, another had gabapentin, and the third was given a starch placebo. The goal was to compare how each treatment affected both pain and anxiety following surgery.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Read More
7
We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 5 Reviews
6.6
- All Reviews
- Positive Reviews
- Negative Reviews
0
Severe side effects
4 people found this helpful
This product did not suit me at all. I felt heat in my limbs but couldn’t sleep, and the next day I was excessively sleepy. After a few attempts, I experienced headaches, nausea, and a sense of dullness, leading me to discard it.
Read More
9
Natural sleep aid
I've ordered this three times, but it causes nausea unlike other types. After taking half a pill, I can fall asleep naturally as if I'm using sleeping pills.
Read More
0
Considerable dizziness
1 people found this helpful
I experienced severe side effects including dizziness, nausea, and headaches. While it’s recommended on blogs, I suggest buying it with caution due to these adverse effects.
Read More
7.5
Improved sleep quality
I regularly buy this as it aids my son with orthostatic disorder. I've taken it since high school and although I still struggle with waking up, my night’s sleep has improved, which, perhaps, helps me wake up better. It’s not a cure for my symptoms, but it helps with sleep quality and I recommend it to others in similar situations.
Read More
0
Not suitable for me
Although it makes me sleepy, waking up is extremely painful as I'm left feeling tired. After taking half a tablet recently, I woke up feeling nauseous and ended up vomiting, so I decided it was unsuitable for me.
Read More
Frequently Asked Questions
7.5
Improved sleep quality
I regularly buy this as it aids my son with orthostatic disorder. I've taken it since high school and although I still struggle with waking up, my night’s sleep has improved, which, perhaps, helps me wake up better. It’s not a cure for my symptoms, but it helps with sleep quality and I recommend it to others in similar situations.
0
Severe side effects
4 people found this helpful
This product did not suit me at all. I felt heat in my limbs but couldn’t sleep, and the next day I was excessively sleepy. After a few attempts, I experienced headaches, nausea, and a sense of dullness, leading me to discard it.
0
Considerable dizziness
1 people found this helpful
I experienced severe side effects including dizziness, nausea, and headaches. While it’s recommended on blogs, I suggest buying it with caution due to these adverse effects.
9
Natural sleep aid
I've ordered this three times, but it causes nausea unlike other types. After taking half a pill, I can fall asleep naturally as if I'm using sleeping pills.
0
Not suitable for me
Although it makes me sleepy, waking up is extremely painful as I'm left feeling tired. After taking half a tablet recently, I woke up feeling nauseous and ended up vomiting, so I decided it was unsuitable for me.
8
Melatonin may reduce postoperative nausea
In a recent clinical trial involving 99 patients undergoing laminectomy, we explored the effectiveness of melatonin on postoperative nausea. Participants were divided into three groups: one received melatonin, another had gabapentin, and the third was given a starch placebo. The goal was to compare how each treatment affected both pain and anxiety following surgery.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
Interestingly, we found that patients in the melatonin group reported less nausea and vomiting compared to other groups. This suggests that melatonin might play a role in easing nausea following surgical procedures.
However, it's important to note that while melatonin showed some benefits for nausea, the overall emphasis of the study was on its comparative effectiveness against gabapentin and dexmedetomidine for pain and anxiety management. Thus, while melatonin seems to help minimize nausea, more research could further clarify its role and effectiveness in diverse settings.
7
We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.
However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.
References
- Jouybar R, Kazemifar S, Asmarian N, Karami A, Khademi S. Comparison of the effect of melatonin, dexmedetomidine, and gabapentin on reduction of postoperative pain and anxiety following laminectomy: a randomized clinical trial. BMC Anesthesiol. 2022;22:318. doi:10.1186/s12871-022-01851-x
- Söderquist F, Janson ET, Rasmusson AJ, Ali A, Stridsberg M, et al. Melatonin Immunoreactivity in Malignant Small Intestinal Neuroendocrine Tumours. PLoS One. 2016;11:e0164354. doi:10.1371/journal.pone.0164354
