Last update
5/1/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 17 Researches
5.9
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
Top Medical Research Studies
We examined whether taking omega-3 fatty acids could enhance the effects of dual antiplatelet therapy for patients dealing with stable angina after heart procedures. Our study involved 40 patients who were split into two groups: one received omega-3 alongside standard medication, while the other did not.
After testing platelet activity over time, we found no significant differences between the two groups. This suggests that omega-3 fish oil does not provide additional benefits for managing chest pain in these patients.
After testing platelet activity over time, we found no significant differences between the two groups. This suggests that omega-3 fish oil does not provide additional benefits for managing chest pain in these patients.
Read More
8
We explored the effects of low-dose fish oil concentrate on patients experiencing angina due to coronary artery disease. In a study with 39 patients, one group received fish oil while the other was given a placebo.
Remarkably, we observed that the fish oil group experienced a 41% reduction in anginal attacks and a significant decrease in medication use over the treatment period. They also enjoyed longer exercise tolerance times and lower serum triglycerides.
Conversely, the placebo group showed no significant changes. Our findings suggest that low-dose fish oil may indeed benefit those struggling with chest pain.
Remarkably, we observed that the fish oil group experienced a 41% reduction in anginal attacks and a significant decrease in medication use over the treatment period. They also enjoyed longer exercise tolerance times and lower serum triglycerides.
Conversely, the placebo group showed no significant changes. Our findings suggest that low-dose fish oil may indeed benefit those struggling with chest pain.
Read More
8
We conducted a trial involving 23 geriatric patients to see if low-dose fish oil could help with angina pectoris.
Using a single-blind, placebo-controlled, crossover design, we discovered that fish oil significantly reduced the number of anginal attacks and the need for sublingual isosorbide dinitrate tablets.
Additionally, there seemed to be a lingering effect of fish oil even after switching to the placebo, suggesting potential long-term benefits.
Using a single-blind, placebo-controlled, crossover design, we discovered that fish oil significantly reduced the number of anginal attacks and the need for sublingual isosorbide dinitrate tablets.
Additionally, there seemed to be a lingering effect of fish oil even after switching to the placebo, suggesting potential long-term benefits.
Read More
Most Useful Reviews
8
No chest pain
I've been taking omega-3 regularly and bought this by chance. I feel more energised, my skin is softer, and the chest pain I had occasionally has disappeared. Without it, discomfort in my knees returns every few weeks, but it’s not severe. I take 2 capsules in the morning with fatty foods.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 17 Researches
5.9
- All Researches
8
We investigated whether adding eicosapentaenoic acid (EPA), an omega-3 fatty acid, to statin therapy could help reduce chest pain linked to coronary heart disease. In this randomized controlled trial involving 193 patients, those taking both EPA and pitavastatin experienced a significant reduction in coronary plaque volume compared to those on statins alone.
While the combination therapy particularly benefited patients with stable angina, it did not reduce major cardiovascular events or side effects. This suggests that while EPA may enhance plaque stability, it does not necessarily lower chest pain symptoms in all cases.
While the combination therapy particularly benefited patients with stable angina, it did not reduce major cardiovascular events or side effects. This suggests that while EPA may enhance plaque stability, it does not necessarily lower chest pain symptoms in all cases.
Read More
8
Fish oil reduces cardiac events
We examined the effects of fish oil on chest pain in a randomized trial involving 360 patients experiencing suspected acute myocardial infarction.
After one year, we found that those taking fish oil had significantly fewer cardiac events and nonfatal infarctions compared to the placebo group.
Interestingly, while fish oil appeared to lower cardiac death rates, mustard oil showed no similar benefit.
Overall, this suggests that fish oil may offer protective effects, though more extensive research is needed for confirmation.
After one year, we found that those taking fish oil had significantly fewer cardiac events and nonfatal infarctions compared to the placebo group.
Interestingly, while fish oil appeared to lower cardiac death rates, mustard oil showed no similar benefit.
Overall, this suggests that fish oil may offer protective effects, though more extensive research is needed for confirmation.
Read More
8
We explored the effects of low-dose fish oil concentrate on patients experiencing angina due to coronary artery disease. In a study with 39 patients, one group received fish oil while the other was given a placebo.
Remarkably, we observed that the fish oil group experienced a 41% reduction in anginal attacks and a significant decrease in medication use over the treatment period. They also enjoyed longer exercise tolerance times and lower serum triglycerides.
Conversely, the placebo group showed no significant changes. Our findings suggest that low-dose fish oil may indeed benefit those struggling with chest pain.
Remarkably, we observed that the fish oil group experienced a 41% reduction in anginal attacks and a significant decrease in medication use over the treatment period. They also enjoyed longer exercise tolerance times and lower serum triglycerides.
Conversely, the placebo group showed no significant changes. Our findings suggest that low-dose fish oil may indeed benefit those struggling with chest pain.
Read More
8
We conducted a trial involving 23 geriatric patients to see if low-dose fish oil could help with angina pectoris.
Using a single-blind, placebo-controlled, crossover design, we discovered that fish oil significantly reduced the number of anginal attacks and the need for sublingual isosorbide dinitrate tablets.
Additionally, there seemed to be a lingering effect of fish oil even after switching to the placebo, suggesting potential long-term benefits.
Using a single-blind, placebo-controlled, crossover design, we discovered that fish oil significantly reduced the number of anginal attacks and the need for sublingual isosorbide dinitrate tablets.
Additionally, there seemed to be a lingering effect of fish oil even after switching to the placebo, suggesting potential long-term benefits.
Read More
8
We examined the long-term effects of a fish lipid concentrate high in eicosapentaenoic acid in 107 subjects, some with heart conditions and others without. Over two years, we noticed marked reductions in triglycerides, a mild decrease in total cholesterol, and an increase in HDL cholesterol.
Notably, we found a significant decrease in the use of GTN tablets, correlating with fewer angina attacks. This suggests that omega-3 may help enhance heart health by reducing symptoms and improving lipid profiles, although bleeding times also increased.
Notably, we found a significant decrease in the use of GTN tablets, correlating with fewer angina attacks. This suggests that omega-3 may help enhance heart health by reducing symptoms and improving lipid profiles, although bleeding times also increased.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8
No chest pain
I've been taking omega-3 regularly and bought this by chance. I feel more energised, my skin is softer, and the chest pain I had occasionally has disappeared. Without it, discomfort in my knees returns every few weeks, but it’s not severe. I take 2 capsules in the morning with fatty foods.
Read More
Frequently Asked Questions
8
No chest pain
I've been taking omega-3 regularly and bought this by chance. I feel more energised, my skin is softer, and the chest pain I had occasionally has disappeared. Without it, discomfort in my knees returns every few weeks, but it’s not severe. I take 2 capsules in the morning with fatty foods.
7
Omega-3 with Statins shows benefits
We explored the impact of adding omega-3 fatty acids to statin therapy, analyzing data from 40,991 patients across 14 studies. Our findings showed that this combination led to lower instances of heart-related issues like myocardial infarction and unstable angina.
However, it’s important to note that there was no significant difference noted in fatal strokes or overall cardiovascular mortality. This suggests that while omega-3 fatty acids may hold promise for improving certain cardiovascular metrics, they do not necessarily correlate with reduced chest pain in terms of severe outcomes.
However, it’s important to note that there was no significant difference noted in fatal strokes or overall cardiovascular mortality. This suggests that while omega-3 fatty acids may hold promise for improving certain cardiovascular metrics, they do not necessarily correlate with reduced chest pain in terms of severe outcomes.
5
We explored the relationship between omega-3 fatty acids and coronary spastic angina (CSA) in patients undergoing testing for chest pain. The study included 406 participants, divided into age-based groups.
In younger patients (≤65 years), those with CSA exhibited higher serum levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) than those without.
In contrast, this association was not observed in older patients. Our findings suggest that higher omega-3 levels may play a role in CSA for younger individuals but not for the elderly.
In younger patients (≤65 years), those with CSA exhibited higher serum levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) than those without.
In contrast, this association was not observed in older patients. Our findings suggest that higher omega-3 levels may play a role in CSA for younger individuals but not for the elderly.
8
We investigated whether adding eicosapentaenoic acid (EPA), an omega-3 fatty acid, to statin therapy could help reduce chest pain linked to coronary heart disease. In this randomized controlled trial involving 193 patients, those taking both EPA and pitavastatin experienced a significant reduction in coronary plaque volume compared to those on statins alone.
While the combination therapy particularly benefited patients with stable angina, it did not reduce major cardiovascular events or side effects. This suggests that while EPA may enhance plaque stability, it does not necessarily lower chest pain symptoms in all cases.
While the combination therapy particularly benefited patients with stable angina, it did not reduce major cardiovascular events or side effects. This suggests that while EPA may enhance plaque stability, it does not necessarily lower chest pain symptoms in all cases.
1
We investigated the effects of eicosapentaenoic acid (EPA)-rich fish oil on patients with stable angina pectoris in a placebo-controlled, double-blind study.
Although we observed favorable changes in blood cell flexibility and viscosity after 3 months of supplementation, there was no significant improvement in chest pain symptoms for either the fish oil or the placebo group.
This suggests that while EPA-rich fish oil can affect certain blood characteristics, it does not appear to alleviate angina discomfort effectively.
Although we observed favorable changes in blood cell flexibility and viscosity after 3 months of supplementation, there was no significant improvement in chest pain symptoms for either the fish oil or the placebo group.
This suggests that while EPA-rich fish oil can affect certain blood characteristics, it does not appear to alleviate angina discomfort effectively.
References
- Irfan A, Haider SH, Nasir A, Larik MO, Naz T. Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of 40,991 Patients. Curr Probl Cardiol. 2024;49:102245. 10.1016/j.cpcardiol.2023.102245
- Tawara K, Akioka H, Sato H, Sato T, Takahashi M, et al. Role of polyunsaturated fatty acids in Japanese patients with coronary spastic angina. J Cardiol. 2023;82:455. 10.1016/j.jjcc.2023.07.001
- Watanabe T, Ando K, Daidoji H, Otaki Y, Sugawara S, et al. A randomized controlled trial of eicosapentaenoic acid in patients with coronary heart disease on statins. J Cardiol. 2017;70:537. 10.1016/j.jjcc.2017.07.007
- Gajos G, Zalewski J, Mostowik M, Konduracka E, Nessler J, et al. Polyunsaturated omega-3 fatty acids reduce lipoprotein-associated phospholipase A(2) in patients with stable angina. Nutr Metab Cardiovasc Dis. 2014;24:434. 10.1016/j.numecd.2013.09.011
- Mizia-Stec K, Mizia M, Haberka M, Lasota B, Gieszczyk-Strózik K, et al. N-3 polyunsaturated fatty acids do not influence the efficacy of dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention. Cardiol J. 2013;20:478. 10.5603/CJ.2013.0132
- Zhao YT, Chen Q, Sun YX, Li XB, Zhang P, et al. Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: a meta-analysis of randomized controlled trials. Ann Med. 2009;41:301. 10.1080/07853890802698834
- Singh RB, Niaz MA, Sharma JP, Kumar R, Rastogi V, et al. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival--4. Cardiovasc Drugs Ther. 1997;11:485. PubMed
- Yamamoto H, Yoshimura H, Noma M, Suzuki S, Kai H, et al. Improvement of coronary vasomotion with eicosapentaenoic acid does not inhibit acetylcholine-induced coronary vasospasm in patients with variant angina. Jpn Circ J. 1995;59:608. PubMed
- Salachas A, Papadopoulos C, Sakadamis G, Styliadis J, Voudris V, et al. Effects of a low-dose fish oil concentrate on angina, exercise tolerance time, serum triglycerides, and platelet function. Angiology. 1994;45:1023. PubMed
- Aucamp AK, Schoeman HS, Coetzee JH. Pilot trial to determine the efficacy of a low dose of fish oil in the treatment of angina pectoris in the geriatric patient. Prostaglandins Leukot Essent Fatty Acids. 1993;49:687. PubMed
- Kalinkina OM, Gratsianskiĭ NA, Perova NV, Metel'skaia VA, Zykova VP, et al. [Newly developed stenocardia: effect of diet with increased amount of polyunsaturated fatty acids of the omega-3 group on blood lipids and apolipoproteins]. Kardiologiia. 1990;30:34. PubMed
- Kalinkina OM, Perova NV, Zykova VP, Gratsianskiĭ NA, Mel'kina OE, et al. [The effect of a diet enriched with omega-3 polyunsaturated fatty acids on thrombocyte functional activity and on the blood lipid-apolipoprotein spectrum in newly occurring stenocardia]. Ter Arkh. 1990;62:77. PubMed
- Solomon SA, Cartwright I, Pockley G, Greaves M, Preston FE, et al. A placebo-controlled, double-blind study of eicosapentaenoic acid-rich fish oil in patients with stable angina pectoris. Curr Med Res Opin. 1990;12:1. PubMed
- Saynor R, Verel D, Gillott T. The long-term effect of dietary supplementation with fish lipid concentrate on serum lipids, bleeding time, platelets and angina. Atherosclerosis. 1984;50:3. PubMed
- Zykova VP, Perova NV, Kalinkina OM. [Study of in vitro thromboxane A2 generation by platelets of patients with first-time appearing angina pectoris under the effect of fish diet]. Kardiologiia. 1990;30:24. PubMed
- Schmidt EB, Kristensen SD, Dyerberg J. The effect of fish oil on lipids, coagulation and fibrinolysis in patients with angina pectoris. Artery. 1988;15:316. PubMed
- Kondo T, Ogawa K, Satake T, Kitazawa M, Taki K, et al. Plasma-free eicosapentaenoic acid/arachidonic acid ratio: a possible new coronary risk factor. Clin Cardiol. 1986;9:413. PubMed
