Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Good
Based on 7 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Calcium (as Dibasic Calcium Phosphate)
32 mg
2%
5-HTP (5-Hydroxytryptophan)[from Griffonia simplicifolia) (seed)
100 mg
*

Top Medical Research Studies

8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
Read More
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
Read More
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.
Read More

Most Useful Reviews

7.5
Emotional balance achieved
32 people found this helpful
Finally, I feel balanced emotionally! I hadn't tried other 5-HTP products but decided to stick with this brand. After researching its efficacy in appetite control, I can confirm it genuinely works. A notable bonus has been alleviating the heavy feeling in my chest from years of stress. Its time-release formula means I don't feel groggy; I take it in the morning to maintain balanced serotonin levels and curb my hunger. As I work on my weight loss journey, it has truly helped me feel stronger and healthier. I will review other products supporting my healthy weight loss, and if you appreciate my input, please let me know!
Read More
7.5
Sleep quality enhanced
5-hydroxytryptophan is a naturally occurring amino acid that aids in converting tryptophan into serotonin. This advanced tryptophan formula rapidly penetrates the brain, enhancing sleep quality and stimulating REM sleep, vital for overall health. Furthermore, it effectively curbs excessive carbohydrate consumption and supports my weight loss efforts. It truly helps with anxiety and improving sleep.
Read More
8
Notable weight reduction
5 people found this helpful
I'm impressed with these tablets. They have replaced Zoloft for me, significantly improving my mood, depression, and anxiety. I’ve also lost about 5 pounds since I started taking them inconsistently. I'm beginning my second bottle and plan to try a higher dose. If you're considering this product, I doubt you'll regret it!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
  • All Researches
8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
Read More
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
Read More
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.
Read More
We explored how obesity specialists prescribe medications including 5-HTP combined with carbidopa. Through an anonymous survey of 266 physicians, we discovered that a significant number recommended this combination for weight loss.

In a small case review, patients lost 16% of their weight with phentermine over six months and an additional 1% with 5-HTP/carbidopa. One participant even experienced a dramatic 24.4% weight loss solely from 5-HTP/carbidopa. However, further controlled studies are necessary to fully understand its effectiveness.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Emotional balance achieved
32 people found this helpful
Finally, I feel balanced emotionally! I hadn't tried other 5-HTP products but decided to stick with this brand. After researching its efficacy in appetite control, I can confirm it genuinely works. A notable bonus has been alleviating the heavy feeling in my chest from years of stress. Its time-release formula means I don't feel groggy; I take it in the morning to maintain balanced serotonin levels and curb my hunger. As I work on my weight loss journey, it has truly helped me feel stronger and healthier. I will review other products supporting my healthy weight loss, and if you appreciate my input, please let me know!
Read More
7.5
Sleep quality enhanced
5-hydroxytryptophan is a naturally occurring amino acid that aids in converting tryptophan into serotonin. This advanced tryptophan formula rapidly penetrates the brain, enhancing sleep quality and stimulating REM sleep, vital for overall health. Furthermore, it effectively curbs excessive carbohydrate consumption and supports my weight loss efforts. It truly helps with anxiety and improving sleep.
Read More
8
Notable weight reduction
5 people found this helpful
I'm impressed with these tablets. They have replaced Zoloft for me, significantly improving my mood, depression, and anxiety. I’ve also lost about 5 pounds since I started taking them inconsistently. I'm beginning my second bottle and plan to try a higher dose. If you're considering this product, I doubt you'll regret it!
Read More
7.5
Highly effective choice
5 people found this helpful
This product stood out based on numerous reviews I read regarding 5-hydroxytryptophanes. It’s deemed the most effective, being a serotonin precursor which helps alleviate anxiety, improve sleep quality, and reduce pain and numbness. It also supports weight loss. I take 200-400 mg at bedtime for sleep and 1-2 daily between meals to enhance my mood and aid weight loss. The recommended course is 6-12 weeks.
Read More
7.5
Appetite control success
1 people found this helpful
Years ago, a naturopathic doctor advised me to take 5-HTP for weight loss, and I recently returned to it for appetite control. I appreciate the time-release formula and will purchase it again.
Read More

Frequently Asked Questions

7.5
Highly effective choice
5 people found this helpful
This product stood out based on numerous reviews I read regarding 5-hydroxytryptophanes. It’s deemed the most effective, being a serotonin precursor which helps alleviate anxiety, improve sleep quality, and reduce pain and numbness. It also supports weight loss. I take 200-400 mg at bedtime for sleep and 1-2 daily between meals to enhance my mood and aid weight loss. The recommended course is 6-12 weeks.
8
Notable weight reduction
5 people found this helpful
I'm impressed with these tablets. They have replaced Zoloft for me, significantly improving my mood, depression, and anxiety. I’ve also lost about 5 pounds since I started taking them inconsistently. I'm beginning my second bottle and plan to try a higher dose. If you're considering this product, I doubt you'll regret it!
7.5
Emotional balance achieved
32 people found this helpful
Finally, I feel balanced emotionally! I hadn't tried other 5-HTP products but decided to stick with this brand. After researching its efficacy in appetite control, I can confirm it genuinely works. A notable bonus has been alleviating the heavy feeling in my chest from years of stress. Its time-release formula means I don't feel groggy; I take it in the morning to maintain balanced serotonin levels and curb my hunger. As I work on my weight loss journey, it has truly helped me feel stronger and healthier. I will review other products supporting my healthy weight loss, and if you appreciate my input, please let me know!
7.5
Sleep quality enhanced
5-hydroxytryptophan is a naturally occurring amino acid that aids in converting tryptophan into serotonin. This advanced tryptophan formula rapidly penetrates the brain, enhancing sleep quality and stimulating REM sleep, vital for overall health. Furthermore, it effectively curbs excessive carbohydrate consumption and supports my weight loss efforts. It truly helps with anxiety and improving sleep.
7.5
Reduced cravings noted
This supplement has a mild sedative effect, elevating my mood. It suppresses cravings for sweets and overall appetite, which is why I utilise it for weight loss.
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
We explored how obesity specialists prescribe medications including 5-HTP combined with carbidopa. Through an anonymous survey of 266 physicians, we discovered that a significant number recommended this combination for weight loss.

In a small case review, patients lost 16% of their weight with phentermine over six months and an additional 1% with 5-HTP/carbidopa. One participant even experienced a dramatic 24.4% weight loss solely from 5-HTP/carbidopa. However, further controlled studies are necessary to fully understand its effectiveness.
8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.

References

  1. Rondanelli M, Klersy C, Iadarola P, Monteferrario F, Opizzi A. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes (Lond). 2009;33:1174. 10.1038/ijo.2009.155
  2. Hendricks EJ, Rothman RB, Greenway FL. How physician obesity specialists use drugs to treat obesity. Obesity (Silver Spring). 2009;17:1730. 10.1038/oby.2009.69
  3. Cangiano C, Ceci F, Cascino A, Del Ben M, Laviano A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr. 1992;56:863.
  4. Itskovitz HD, Werber JL, Sheridan AM, Brewer TF, Stier CT. 5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats. J Hypertens. 1989;7:311.
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