Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Biotin
10,000 mcg
33,333%
Top Medical Research Studies
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More
Most Useful Reviews
0
Eczema onset concerns
1 people found this helpful
Is 10,000mcg too much? I took one pill daily due to its pleasant taste, but developed a large eczema on the left side of my face that hurts to touch. The area below my left earlobe also became swollen and painful, reminiscent of mumps. From reading reviews, it seems others have had similar experiences. I have a chronic immune system disease, which may contribute. After about half a month, there was no effect on my skin or hair, so I ceased taking it. I'm quite disappointed.
Read More
9
Improved eczema condition
1 people found this helpful
It works well on nails, and the strawberry flavour is delightful. I've been dealing with housewife eczema, but now that I'm taking this, my condition has improved!
Read More
1
Triggered eczema issue
I switched from Sports Research brand to this product as I was really keen on biotin. While it did help me, it also triggered my eczema, forcing me to stop after two weeks.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
- All Researches
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More
8
We examined a rare condition called holocarboxylase synthetase (HLCS) deficiency, which affects biotin metabolism in patients. Our study focused on five patients diagnosed between 2015 and 2024.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Read More
7
We explored how biotin treatment affects patients with biotinidase deficiency, focusing on their clinical features, which include skin conditions like eczema. In our study, six patients ranging from only a few months old to 14 years displayed a variety of neurological and dermatological symptoms.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
0
Eczema onset concerns
1 people found this helpful
Is 10,000mcg too much? I took one pill daily due to its pleasant taste, but developed a large eczema on the left side of my face that hurts to touch. The area below my left earlobe also became swollen and painful, reminiscent of mumps. From reading reviews, it seems others have had similar experiences. I have a chronic immune system disease, which may contribute. After about half a month, there was no effect on my skin or hair, so I ceased taking it. I'm quite disappointed.
Read More
9
Improved eczema condition
1 people found this helpful
It works well on nails, and the strawberry flavour is delightful. I've been dealing with housewife eczema, but now that I'm taking this, my condition has improved!
Read More
1
Triggered eczema issue
I switched from Sports Research brand to this product as I was really keen on biotin. While it did help me, it also triggered my eczema, forcing me to stop after two weeks.
Read More
Frequently Asked Questions
9
Improved eczema condition
1 people found this helpful
It works well on nails, and the strawberry flavour is delightful. I've been dealing with housewife eczema, but now that I'm taking this, my condition has improved!
0
Eczema onset concerns
1 people found this helpful
Is 10,000mcg too much? I took one pill daily due to its pleasant taste, but developed a large eczema on the left side of my face that hurts to touch. The area below my left earlobe also became swollen and painful, reminiscent of mumps. From reading reviews, it seems others have had similar experiences. I have a chronic immune system disease, which may contribute. After about half a month, there was no effect on my skin or hair, so I ceased taking it. I'm quite disappointed.
1
Triggered eczema issue
I switched from Sports Research brand to this product as I was really keen on biotin. While it did help me, it also triggered my eczema, forcing me to stop after two weeks.
9.5
Biotin treatment for eczema effectiveness
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.
This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
9
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.
Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
7
We explored how biotin treatment affects patients with biotinidase deficiency, focusing on their clinical features, which include skin conditions like eczema. In our study, six patients ranging from only a few months old to 14 years displayed a variety of neurological and dermatological symptoms.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.
While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
9.5
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.
This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
8
We examined a rare condition called holocarboxylase synthetase (HLCS) deficiency, which affects biotin metabolism in patients. Our study focused on five patients diagnosed between 2015 and 2024.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
Each patient presented with skin rashes and severe symptoms, including respiratory distress and seizures. Remarkably, four out of five patients showed improvement with biotin therapy, receiving daily doses of 10-30 mg that helped maintain their metabolic health.
This study highlights the importance of early detection and intervention with biotin to prevent serious complications, making a strong case for screening specific gene mutations in affected individuals.
References
- Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
- Hagiwara SI, Kubota M, Nambu R, Kagimoto S. Screening of carnitine and biotin deficiencies on tandem mass spectrometry. Pediatr Int. 2017;59:458. doi:10.1111/ped.13167
- Yang YL, Yamaguchi S, Tagami Y, Zhang YH, Xiong H, et al. [Diagnosis and treatment of biotinidase deficiency-clinical study of six patients]. Zhonghua Er Ke Za Zhi. 2003;41:249.
- Kimura M, Fukui T, Tagami Y, Fujiwaki T, Yokoyama M, et al. Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation. J Inherit Metab Dis. 2003;26:715.
- Ting SL, Yakob Y, Sani HA, Rethanavelu K, Ngu LH. Holocarboxylase Synthetase Deficiency: Clinical, Biochemical and Molecular Findings in Five Malaysian Patients Including a Newborn Presenting as Collodion Baby. JIMD Rep. 2025;66:e70006. doi:10.1002/jmd2.70006
