' 
SCIENTIFIC SCORE
Moderately Effective
Based on 22 Researches
8.3
USERS' SCORE
Good
Based on 11 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B-12 (as Cyanocobalamin)
5,000 mcg
208,330%
Top Medical Research Studies
9
B12 alleviates low back pain
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Significant positive treatment effects
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
Read More
9
Vitamin B12 aids low back pain
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Study focuses on isolated treatment
We conducted a thorough investigation to understand whether intramuscular vitamin B12 treatment could effectively relieve low back pain. This study was designed as a double-blind, placebo-controlled trial involving 60 patients aged 18 to 65 who suffered from mechanical low back pain or sciatic neuritis. Each participant had a history of back pain lasting from six months to five years and reported significant pain intensity according to a standard scale.
By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.
Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.
By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.
Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.
Read More
9
Vitamin B12 reverses back pain
Progressive Decrease in Function and Ambulation Potential: A Case of Subacute Combined Degeneration.
Moderate relevance to back pain
We explored the effects of vitamin B12 treatment on a patient experiencing severe back pain, along with other symptoms associated with subacute combined degeneration (SCD) from prolonged vitamin B12 deficiency. This case involved a 49-year-old man who faced a year of worsening weakness, pain, and gait abnormalities.
Upon diagnosis, he began receiving intramuscular vitamin B12 injections. Remarkably, within weeks, we observed significant improvements in his pain levels and mobility. This underscores the importance of recognizing vitamin B12 deficiency early since it can lead to debilitating conditions but is often reversible through timely treatment.
Our findings highlight how addressing nutrient deficiencies can enhance overall health and well-being. In this specific case, vitamin B12 not only alleviated back pain but also restored functioning, improving quality of life for the patient.
Upon diagnosis, he began receiving intramuscular vitamin B12 injections. Remarkably, within weeks, we observed significant improvements in his pain levels and mobility. This underscores the importance of recognizing vitamin B12 deficiency early since it can lead to debilitating conditions but is often reversible through timely treatment.
Our findings highlight how addressing nutrient deficiencies can enhance overall health and well-being. In this specific case, vitamin B12 not only alleviated back pain but also restored functioning, improving quality of life for the patient.
Read More
Most Useful Reviews
9.5
Reduced back pain
I had severe back pain and numbness, and thanks to this supplement, the numbness has disappeared. Although the pain subsided temporarily, it has returned, so I take it during the worst times. I struggled to walk for quite a while, and I wish I had found this supplement sooner.
Read More
9.5
Minimal back pain
My severe back pain has improved significantly. Despite treatment at an orthopedic clinic, the pain persisted until I tried this vitamin B12 supplement. From day one, my pain dropped from 8/10 to about 2/10. Now, after a month of daily use, I have almost no pain.
Read More
10
Complete back pain relief
I experienced back pain for two years with various treatments but found relief with this vitamin B12 supplement. By the end of the bottle, my pain had completely gone, allowing me to stop frequent visits to the clinic. I believe this was essential for my recovery.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 22 Researches
8.3
- All Researches
9.5
Mannitol and vitamin B12 improve PS
Effect of Mannitol plus Vitamins B in the management of patients with piriformis syndrome.
Combination may obscure B12 effects.
We investigated the impact of a treatment combining mannitol and vitamin B on piriformis syndrome (PS), which is characterized by sciatic nerve entrapment. In a study involving 22 patients, participants received a five-day intravenous infusion of mannitol alongside a six-week regimen of vitamin B, including B1, B2, and B12.
Our observations highlighted significant improvements in clinical assessments, particularly in tenderness and pain levels assessed by various tests and scales. Notably, the Numeric Rating Scale demonstrated a marked reduction in pain at rest, at night, and during activities, which were all statistically significant. Additionally, the swelling around the sciatic nerve also showed a noteworthy decrease.
While vitamin B12 was part of this combination treatment, we must acknowledge that the study's focus on mannitol alongside the vitamins makes it challenging to isolate vitamin B12's specific effects on back pain alone.
Nevertheless, the results suggest that the combined approach might be a promising alternative for managing PS effectively.
Our observations highlighted significant improvements in clinical assessments, particularly in tenderness and pain levels assessed by various tests and scales. Notably, the Numeric Rating Scale demonstrated a marked reduction in pain at rest, at night, and during activities, which were all statistically significant. Additionally, the swelling around the sciatic nerve also showed a noteworthy decrease.
While vitamin B12 was part of this combination treatment, we must acknowledge that the study's focus on mannitol alongside the vitamins makes it challenging to isolate vitamin B12's specific effects on back pain alone.
Nevertheless, the results suggest that the combined approach might be a promising alternative for managing PS effectively.
Read More
9
B12 alleviates low back pain
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Significant positive treatment effects
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
Read More
9
Mixed results from vitamin treatment
[Complaints in the lumbosacral region and their management with Dolo-Neurobion].
Relevant treatment evaluation
We investigated the effectiveness of Dolo-Neurobion, a combination of vitamins B1, B6, and B12 along with an analgesic, for patients with acute lumbosacral pain. The treatment began with a parenteral application followed by oral dosing.
Out of 53 patients, we observed that 77.4% experienced good to excellent relief from their pain, while 15.1% noted moderate effects. There were no notable side effects, which makes this treatment a viable option for managing pain associated with intrapelvic organ issues.
Out of 53 patients, we observed that 77.4% experienced good to excellent relief from their pain, while 15.1% noted moderate effects. There were no notable side effects, which makes this treatment a viable option for managing pain associated with intrapelvic organ issues.
Read More
9
Dexamethasone and B12 improve recovery
Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.
Vitamin B12 effects are combined
We explored the effects of combining dexamethasone with vitamin B12 during epidural injections in patients undergoing a specific type of spinal surgery, known as percutaneous endoscopic interlaminar discectomy (PEID). This study aimed to determine whether this combination could alleviate low back and leg pain that often lingers after the surgery. Patients were randomly assigned to two groups: one received only the surgery (the single surgery group), while the other received the surgery along with the combined treatment of medication.
We found that patients who received the combination of dexamethasone and vitamin B12 experienced a notable reduction in early postoperative pain, which we measured using various scoring systems. Additionally, the injections appeared to decrease the levels of certain inflammatory factors in the body, suggesting a potential biological mechanism behind the relief they experienced. Early recovery metrics, like hospital stay duration and overall satisfaction, were also improved in those receiving the combined treatment.
Therefore, the results encourage considering the use of vitamin B12 along with dexamethasone for patients recovering from disc surgery, as it seems to enhance their recovery experience effectively.
We found that patients who received the combination of dexamethasone and vitamin B12 experienced a notable reduction in early postoperative pain, which we measured using various scoring systems. Additionally, the injections appeared to decrease the levels of certain inflammatory factors in the body, suggesting a potential biological mechanism behind the relief they experienced. Early recovery metrics, like hospital stay duration and overall satisfaction, were also improved in those receiving the combined treatment.
Therefore, the results encourage considering the use of vitamin B12 along with dexamethasone for patients recovering from disc surgery, as it seems to enhance their recovery experience effectively.
Read More
9
Vitamin B12 reverses back pain
Progressive Decrease in Function and Ambulation Potential: A Case of Subacute Combined Degeneration.
Moderate relevance to back pain
We explored the effects of vitamin B12 treatment on a patient experiencing severe back pain, along with other symptoms associated with subacute combined degeneration (SCD) from prolonged vitamin B12 deficiency. This case involved a 49-year-old man who faced a year of worsening weakness, pain, and gait abnormalities.
Upon diagnosis, he began receiving intramuscular vitamin B12 injections. Remarkably, within weeks, we observed significant improvements in his pain levels and mobility. This underscores the importance of recognizing vitamin B12 deficiency early since it can lead to debilitating conditions but is often reversible through timely treatment.
Our findings highlight how addressing nutrient deficiencies can enhance overall health and well-being. In this specific case, vitamin B12 not only alleviated back pain but also restored functioning, improving quality of life for the patient.
Upon diagnosis, he began receiving intramuscular vitamin B12 injections. Remarkably, within weeks, we observed significant improvements in his pain levels and mobility. This underscores the importance of recognizing vitamin B12 deficiency early since it can lead to debilitating conditions but is often reversible through timely treatment.
Our findings highlight how addressing nutrient deficiencies can enhance overall health and well-being. In this specific case, vitamin B12 not only alleviated back pain but also restored functioning, improving quality of life for the patient.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduced back pain
I had severe back pain and numbness, and thanks to this supplement, the numbness has disappeared. Although the pain subsided temporarily, it has returned, so I take it during the worst times. I struggled to walk for quite a while, and I wish I had found this supplement sooner.
9.5
Minimal back pain
My severe back pain has improved significantly. Despite treatment at an orthopedic clinic, the pain persisted until I tried this vitamin B12 supplement. From day one, my pain dropped from 8/10 to about 2/10. Now, after a month of daily use, I have almost no pain.
10
Complete back pain relief
I experienced back pain for two years with various treatments but found relief with this vitamin B12 supplement. By the end of the bottle, my pain had completely gone, allowing me to stop frequent visits to the clinic. I believe this was essential for my recovery.
8.3
Relieved back pain
I purchased this for relief from my persistent back pain. It has a pleasant strawberry flavour and has indeed helped to lessen the pain and numbness in my back.
8.3
Resolved back pain
I took this with the hope of addressing oral tearing, and it has successfully resolved, allowing me to focus on my back pain instead.
