Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
USERS' SCORE
Good
Based on 40 Reviews
8.2
Supplement Facts
Serving Size: 3 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Total Carbohydrate
2 g
1%**
Protein
less than 1 g
Reducol Plant sterols/stanols (as esters)††
900 mg
*
Pantethine (Pantesin)
300 mg
*
Top Medical Research Studies
9.5
We explored the effectiveness of Evinacumab, a monoclonal antibody recently approved for treating severe high cholesterol. Our focus was on a 16-year-old girl from North India diagnosed with homozygous familial hypercholesterolemia (HoFH) at the tender age of two. Despite her long-standing battle with high cholesterol, traditional treatments, including medications and lifestyle changes, failed to bring her cholesterol levels down to the recommended guidelines.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Read More
Most Useful Reviews
10
Cholesterol normalised
15 people found this helpful
The result is positive. After two months of taking it alongside other supplements like rice, phytosterols, and omega, my cholesterol, which was critical, became normal. Omega and rice alone didn’t work. My husband also refused statins (which he had taken for three years) and his indicators are now normal.
Read More
10
Cholesterol normalised
10 people found this helpful
For the first time in 20 years, my cholesterol is normal! It decreased by 54 points and my triglycerides by 68 since my last test. I've taken this product consistently, and it's the only supplement I use for lowering cholesterol. I firmly believe in it!
Read More
9
Significant reduction achieved
10 people found this helpful
In my case, the product worked well. Over a month, my cholesterol dropped from 12 to 6.95, aided by this supplement, a better diet, and increased exercise. I monitored my cholesterol weekly and saw clear positive results.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
- All Researches
9.5
We explored the effectiveness of Evinacumab, a monoclonal antibody recently approved for treating severe high cholesterol. Our focus was on a 16-year-old girl from North India diagnosed with homozygous familial hypercholesterolemia (HoFH) at the tender age of two. Despite her long-standing battle with high cholesterol, traditional treatments, including medications and lifestyle changes, failed to bring her cholesterol levels down to the recommended guidelines.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Read More
User Reviews
USERS' SCORE
Good
Based on 40 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
10
Cholesterol normalised
15 people found this helpful
The result is positive. After two months of taking it alongside other supplements like rice, phytosterols, and omega, my cholesterol, which was critical, became normal. Omega and rice alone didn’t work. My husband also refused statins (which he had taken for three years) and his indicators are now normal.
Read More
10
Cholesterol normalised
10 people found this helpful
For the first time in 20 years, my cholesterol is normal! It decreased by 54 points and my triglycerides by 68 since my last test. I've taken this product consistently, and it's the only supplement I use for lowering cholesterol. I firmly believe in it!
Read More
9
Significant reduction achieved
10 people found this helpful
In my case, the product worked well. Over a month, my cholesterol dropped from 12 to 6.95, aided by this supplement, a better diet, and increased exercise. I monitored my cholesterol weekly and saw clear positive results.
Read More
7.5
Good supplement effect
10 people found this helpful
Good supplement. My cholesterol fell from 6.70 to 5.24 within a month, but it rose again later. After switching to one capsule daily, my levels improved further, dropping to 4.80. I've tried various remedies without success, so I recommend this supplement to others, as it may work for you.
Read More
7.5
Husband's cholesterol lowered
6 people found this helpful
I bought this product for my husband, who has hereditary high cholesterol. After switching from a prescription statin, his cholesterol levels decreased according to recent blood tests. He shared this with his doctor, who acknowledged its effectiveness. I feel relieved now.
Read More
Frequently Asked Questions
10
Cholesterol normalised
10 people found this helpful
For the first time in 20 years, my cholesterol is normal! It decreased by 54 points and my triglycerides by 68 since my last test. I've taken this product consistently, and it's the only supplement I use for lowering cholesterol. I firmly believe in it!
7.5
Self-treatment successful
6 people found this helpful
My cholesterol was high at my last check-up. I wanted to avoid statins, so I changed my diet, exercised, and took Cholestoff Complete. I successfully reduced my overall cholesterol from 284 to 233, and LDL from 203.2 to 160.4 in just 12 weeks!
10
Cholesterol normalised
15 people found this helpful
The result is positive. After two months of taking it alongside other supplements like rice, phytosterols, and omega, my cholesterol, which was critical, became normal. Omega and rice alone didn’t work. My husband also refused statins (which he had taken for three years) and his indicators are now normal.
7.5
Husband's cholesterol lowered
6 people found this helpful
I bought this product for my husband, who has hereditary high cholesterol. After switching from a prescription statin, his cholesterol levels decreased according to recent blood tests. He shared this with his doctor, who acknowledged its effectiveness. I feel relieved now.
7.5
LDL decreased
5 people found this helpful
My LDL cholesterol decreased from 188 to 139 after using this supplement for a month. However, I switched to a cheaper option briefly, and my levels rose again. I've now returned to this supplement and my cholesterol is normal, which is reassuring.
9
Significant reduction
3 people found this helpful
This isn't a magic supplement; results aren't instant. My high cholesterol level was over 580, but after taking this from around April, it's now down to 145 without changing my diet.
7.5
Effective product
1 people found this helpful
It works! 😁 This is a good product. If you give it time and adjust your diet a bit, it can lower your "bad" cholesterol levels. Take the softgels as directed and allow them a month or two to see a difference in your blood tests.
9
Significant reduction achieved
10 people found this helpful
In my case, the product worked well. Over a month, my cholesterol dropped from 12 to 6.95, aided by this supplement, a better diet, and increased exercise. I monitored my cholesterol weekly and saw clear positive results.
7.5
Good supplement effect
10 people found this helpful
Good supplement. My cholesterol fell from 6.70 to 5.24 within a month, but it rose again later. After switching to one capsule daily, my levels improved further, dropping to 4.80. I've tried various remedies without success, so I recommend this supplement to others, as it may work for you.
9
Remarkable effect
1 people found this helpful
This really works; my cholesterol dropped by 100 points!
7.5
Consistent improvement
4 people found this helpful
This product is working for me. I've been taking it for six weeks, and my cholesterol levels have lowered. I will continue to use it.
9.5
We explored the effectiveness of Evinacumab, a monoclonal antibody recently approved for treating severe high cholesterol. Our focus was on a 16-year-old girl from North India diagnosed with homozygous familial hypercholesterolemia (HoFH) at the tender age of two. Despite her long-standing battle with high cholesterol, traditional treatments, including medications and lifestyle changes, failed to bring her cholesterol levels down to the recommended guidelines.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
References
- Arora S, Banerjee S, George A, Bala A, Thingnam SKS, et al. Dramatic response to Evinacumab in a North Indian girl with homozygous familial hypercholesterolemia. J Pediatr Endocrinol Metab. 2025;38:305. doi:10.1515/jpem-2024-0506
