Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 20 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
250 mg
60%
Top Medical Research Studies
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
9
Improved heart health
43 people found this helpful
This medication has benefits for bone density, heart rate management, and preventing heart disease. I found that my sleep returned to normal on the first day, and my irritability vanished. I've noticed increased efficiency, concentration, and a sense of well-being. Overall, I highly recommend it.
Read More
9
Improved sleep quality
2 people found this helpful
These vitamins are of excellent quality and have no side effects. Magnesium normalises heart rate, lowers blood pressure, and helps eliminate muscle cramps. Since I started taking it, my insomnia has improved, and muscle cramping is less frequent, providing significant benefits for my heart health.
Read More
9
Blood pressure reduction
1 people found this helpful
This supplement is beneficial for my mother, who experiences high blood pressure and heart issues. After starting it, her blood pressure dropped significantly. The quality is excellent, and the small tablets are easy to swallow. Overall, it's crucial for heart health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved heart health
43 people found this helpful
This medication has benefits for bone density, heart rate management, and preventing heart disease. I found that my sleep returned to normal on the first day, and my irritability vanished. I've noticed increased efficiency, concentration, and a sense of well-being. Overall, I highly recommend it.
Read More
9
Improved sleep quality
2 people found this helpful
These vitamins are of excellent quality and have no side effects. Magnesium normalises heart rate, lowers blood pressure, and helps eliminate muscle cramps. Since I started taking it, my insomnia has improved, and muscle cramping is less frequent, providing significant benefits for my heart health.
Read More
9
Blood pressure reduction
1 people found this helpful
This supplement is beneficial for my mother, who experiences high blood pressure and heart issues. After starting it, her blood pressure dropped significantly. The quality is excellent, and the small tablets are easy to swallow. Overall, it's crucial for heart health.
Read More
9
Heart health benefits
Nature Made Magnesium 250 mg tablets are excellent for relaxation, muscle function, and supporting heart health. Each tablet is gluten-free and has no artificial ingredients. I take one with a meal, as advised.
Read More
7.5
Heart rhythm regulation
23 people found this helpful
Magnesium is essential for heart health and helps manage blood pressure and reduce bad cholesterol, thus lowering the risk of heart disease. I find it helps relieve stress and improves my overall mood. While the oxide form may not absorb as well, I still feel its benefits, especially in alleviating headaches related to my dystonia.
Read More
Frequently Asked Questions
7.5
Reduced nervousness
21 people found this helpful
I'm pleased with this magnesium supplement. It helped ease my nervousness and improved my sleep quality after two weeks of consistent use. The price is reasonable, and I plan to continue taking it as it supports my heart and reduces my fatigue.
9
Blood pressure reduction
1 people found this helpful
This supplement is beneficial for my mother, who experiences high blood pressure and heart issues. After starting it, her blood pressure dropped significantly. The quality is excellent, and the small tablets are easy to swallow. Overall, it's crucial for heart health.
9
Improved heart health
43 people found this helpful
This medication has benefits for bone density, heart rate management, and preventing heart disease. I found that my sleep returned to normal on the first day, and my irritability vanished. I've noticed increased efficiency, concentration, and a sense of well-being. Overall, I highly recommend it.
9
Improved sleep quality
2 people found this helpful
These vitamins are of excellent quality and have no side effects. Magnesium normalises heart rate, lowers blood pressure, and helps eliminate muscle cramps. Since I started taking it, my insomnia has improved, and muscle cramping is less frequent, providing significant benefits for my heart health.
9
Supports heart health
I regularly take magnesium to support my heart and nervous system health. This highly absorbable form is taken at night, and I have noticed great benefits.
7.5
Enhanced resilience
1 people found this helpful
Nature Made Magnesium Tablets support heart, muscle, and nervous system health. Since I started taking them, I've experienced improved sleep quality and increased energy levels, leading to a better overall emotional and physical resilience.
7.5
Beneficial for heart
1 people found this helpful
I highly recommend Magnesium vitamins as they contain essential minerals and vitamins. Magnesium plays a crucial role in bone health and heart health, regulates blood pressure, and alleviates muscle cramps. This supplement is effective for overall well-being.
7.5
Aids heart health
My doctor recommended a daily dosage of magnesium for better sleep and to alleviate muscle fatigue. It effectively helps with heart disease and promotes restful sleep.
7.5
Prevention of heart disease
1 people found this helpful
We regularly purchase this magnesium as doctors recommend it for heart health. It helps regulate heart rhythm, stabilise blood pressure, and reduce cholesterol, thus lowering the risk of heart disease. It also enhances sleep quality and overall body function.
9
Heart health benefits
Nature Made Magnesium 250 mg tablets are excellent for relaxation, muscle function, and supporting heart health. Each tablet is gluten-free and has no artificial ingredients. I take one with a meal, as advised.
7.5
Lowered heart attack risk
3 people found this helpful
Magnesium strengthens the heart muscle and helps regulate heartbeat, reducing the risk of heart disease and strokes. It also aids in controlling cholesterol levels, contributing to better blood circulation overall.
6
Stress management
2 people found this helpful
Be aware that this magnesium comes in an oxide form, which has low bioavailability. Nonetheless, it's beneficial for those with a deficiency. I find it offers stress relief and helps normalise my heart rate and blood pressure.
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
References
- Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. doi:10.1161/JAHA.124.038870
- Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. doi:10.1093/ckj/sfae390
- Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. doi:10.6133/apjcn.202502_34(1).0010
- Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. doi:10.1038/s41598-025-85931-1
- Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. doi:10.1684/mrh.2024.0528
- Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. doi:10.1186/s12889-024-20785-2
- Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. doi:10.3390/nu16213617
- Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. doi:10.1371/journal.pone.0313352
- Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. doi:10.1038/s41598-024-74325-4
- Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. doi:10.4244/EIJ-D-24-00055
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
- Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. doi:10.1093/eurjpc/zwae251
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. doi:10.1684/mrh.2024.0517
- Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. doi:10.3390/ijerph21070932
- Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. doi:10.1080/00015385.2024.2379682
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. doi:10.1186/s12951-024-02685-0
