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Nature Made Magnesium Oxide
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 20 Reviews
8.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
250 mg
60%

Top Medical Research Studies

7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
Findings support further investigation
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.

In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.

Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
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9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
High relevance to heart health
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.

Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.

Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
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8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
High relevance for cardiovascular research
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.

This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
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Most Useful Reviews

9.5
Improved heart health
This medication has benefits for bone density, heart rate management, and preventing heart disease. I found that my sleep returned to normal on the first day, and my irritability vanished. I've noticed increased efficiency, concentration, and a sense of well-being. Overall, I highly recommend it.
Read More
9.5
Improved sleep quality
These vitamins are of excellent quality and have no side effects. Magnesium normalises heart rate, lowers blood pressure, and helps eliminate muscle cramps. Since I started taking it, my insomnia has improved, and muscle cramping is less frequent, providing significant benefits for my heart health.
Read More
9.5
Blood pressure reduction
This supplement is beneficial for my mother, who experiences high blood pressure and heart issues. After starting it, her blood pressure dropped significantly. The quality is excellent, and the small tablets are easy to swallow. Overall, it's crucial for heart health.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
  • All Researches
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
High relevance to heart health
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.

Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.

Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
High relevance for cardiovascular research
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.

This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study.
Moderate relevance for heart health.
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.

Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
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8
Magnesium and potassium reduce BP
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
Moderately relevant findings
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.

However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
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8
Calcium-Magnesium Ratio Predicts Prognosis
Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome.
High relevance of findings
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.

By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.

Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
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User Reviews

USERS' SCORE
Good
Based on 20 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Improved heart health
This medication has benefits for bone density, heart rate management, and preventing heart disease. I found that my sleep returned to normal on the first day, and my irritability vanished. I've noticed increased efficiency, concentration, and a sense of well-being. Overall, I highly recommend it.
Read More
9.5
Improved sleep quality
These vitamins are of excellent quality and have no side effects. Magnesium normalises heart rate, lowers blood pressure, and helps eliminate muscle cramps. Since I started taking it, my insomnia has improved, and muscle cramping is less frequent, providing significant benefits for my heart health.
Read More
9.5
Blood pressure reduction
This supplement is beneficial for my mother, who experiences high blood pressure and heart issues. After starting it, her blood pressure dropped significantly. The quality is excellent, and the small tablets are easy to swallow. Overall, it's crucial for heart health.
9.5
Heart health benefits
Nature Made Magnesium 250 mg tablets are excellent for relaxation, muscle function, and supporting heart health. Each tablet is gluten-free and has no artificial ingredients. I take one with a meal, as advised.
8.8
Heart rhythm regulation
Magnesium is essential for heart health and helps manage blood pressure and reduce bad cholesterol, thus lowering the risk of heart disease. I find it helps relieve stress and improves my overall mood. While the oxide form may not absorb as well, I still feel its benefits, especially in alleviating headaches related to my dystonia.
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