Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 18 Reviews
8.4
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
250 mg
60%

Top Medical Research Studies

8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More

Most Useful Reviews

9
Mood enhancement
243 people found this helpful
Periodically, I purchase this magnesium. It’s a great price and dosage. The quality is satisfactory – I take it for about two months. It significantly improves my mood, especially during premenstrual syndrome, normalises sleep, and alleviates anxiety. Previously, I often experienced muscle cramps in my feet, but I no longer feel this. I feel more energised, and the benefits are clear.
Read More
9
Sleep quality improvement
10 people found this helpful
It’s beautiful and helps me sleep. You can't imagine how it regulates my magnesium levels and aids sleep at a great price. After taking it, my brother noticed a difference in just two days, as it alleviated his fatigue and improved his activity and sleep quality.
Read More
9
Fatigue reduction
2 people found this helpful
I received it quickly within two weeks before St. Petersburg. We started taking it, and within three days, my mother slept peacefully and my fatigue diminished. I will definitely order more.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
  • All Researches
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 18 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Mood enhancement
243 people found this helpful
Periodically, I purchase this magnesium. It’s a great price and dosage. The quality is satisfactory – I take it for about two months. It significantly improves my mood, especially during premenstrual syndrome, normalises sleep, and alleviates anxiety. Previously, I often experienced muscle cramps in my feet, but I no longer feel this. I feel more energised, and the benefits are clear.
Read More
9
Sleep quality improvement
10 people found this helpful
It’s beautiful and helps me sleep. You can't imagine how it regulates my magnesium levels and aids sleep at a great price. After taking it, my brother noticed a difference in just two days, as it alleviated his fatigue and improved his activity and sleep quality.
Read More
9
Fatigue reduction
2 people found this helpful
I received it quickly within two weeks before St. Petersburg. We started taking it, and within three days, my mother slept peacefully and my fatigue diminished. I will definitely order more.
Read More
9
Symptoms alleviation
1 people found this helpful
Magnesium positively affects bone growth, heart rate, blood pressure, and blood sugar levels. It reduces muscle cramps and joint pain. I recommend Nature Made Magnesium; it's essential for me. It addresses various symptoms, including chronic fatigue syndrome, and lasts three months at a low price.
Read More
9
Muscle cramp prevention
1 people found this helpful
Magnesium is essential for health, supporting the cardiovascular and nervous systems. My husband uses it to maintain mineral balance on his ketogenic diet. It makes keto adaptation easier and prevents chronic fatigue syndrome related muscle cramps while helping me relax and sleep.
Read More

Frequently Asked Questions

9
Sleep quality improvement
10 people found this helpful
It’s beautiful and helps me sleep. You can't imagine how it regulates my magnesium levels and aids sleep at a great price. After taking it, my brother noticed a difference in just two days, as it alleviated his fatigue and improved his activity and sleep quality.
9
Fatigue reduction
2 people found this helpful
I received it quickly within two weeks before St. Petersburg. We started taking it, and within three days, my mother slept peacefully and my fatigue diminished. I will definitely order more.
9
Mood enhancement
243 people found this helpful
Periodically, I purchase this magnesium. It’s a great price and dosage. The quality is satisfactory – I take it for about two months. It significantly improves my mood, especially during premenstrual syndrome, normalises sleep, and alleviates anxiety. Previously, I often experienced muscle cramps in my feet, but I no longer feel this. I feel more energised, and the benefits are clear.
9
Reduced irritability
This magnesium supplement works well for me. I take it once at night, and it has significantly reduced my fatigue and improved my sleep. I'm less irritable now.
9
Muscle cramp prevention
1 people found this helpful
Magnesium is essential for health, supporting the cardiovascular and nervous systems. My husband uses it to maintain mineral balance on his ketogenic diet. It makes keto adaptation easier and prevents chronic fatigue syndrome related muscle cramps while helping me relax and sleep.
7.5
Improved sleep quality
Good quality, size, taste, and packaging. Magnesium aids calcium and vitamin B assimilation. It alleviates muscle fatigue and enhances sleep while positively impacting joints. A necessary mineral for overall health.
7.5
Improved mood
166 people found this helpful
This magnesium helps replenish my deficiency, improves my mood, and normalises sleep. It alleviates irritability and fatigue while eliminating muscle spasms. The packaging lasts a long time, and I find the quality and taste excellent.
7.5
Fatigue relief
3 people found this helpful
Thanks to the carefully developed formula, one capsule provides the daily requirement of magnesium. This complex is essential for muscle function, nerve impulses, and protecting against vascular diseases. It relieves fatigue and chronic fatigue syndrome. I recommend taking it during meals.
7.5
Muscle fatigue relief
A useful mineral for addressing sleep issues and muscle fatigue. My doctor suggested a 400 mg daily dose, and I take it before bed. It has notably improved my sleep quality and alleviated muscle aches.
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.

References

  1. Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
  2. Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
  3. Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
  4. Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
  5. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
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