We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
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We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.
After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
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Vitamin B1 showed promise for dysmenorrheaThe effects of fish oil capsules and vitamin B1 tablets on duration and severity of dysmenorrhea in students of high school in Urmia-Iran.
Relevant due to clinical trial design
We explored the effects of vitamin B1 and fish oil on dysmenorrhea in high school students. Conducting a double-blind clinical trial, we observed 240 female students divided into four groups, receiving vitamin B1, fish oil, both, or a placebo over two months.
The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
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We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.
Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.
Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
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