5/14/2025
Last update
5/14/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Magnesium(from 513 mg Buffered Magnesium Glycinate Chelate Complex [Magnesium Oxide and Magnesium Bisglycinate])
200 mg
48%
Magnesium-Rich Plants BlendOrganic Spinach LeafOrganic Chard LeafOrganic Okra FruitOrganic Quinoa Grain (Chenopodium quinoa)Organic Black Bean (Phaseolus vulgaris)Organic Pumpkin SeedOrganic Sunflower SeedOrganic Flaxseed
30 mg
**
Top Medical Research Studies
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
9
Great overall health
2 people found this helpful
This brand lives up to its claims about supporting healthy bones, heart, and relieving stress. Personally, I’ve experienced improved sleep as it calms both my mind and muscles, significantly enhancing my overall health.
Read More
9
Prevents heart disease
1 people found this helpful
Critical to health, magnesium is often deficient in many people. Naturelo is known for its quality supplements. Magnesium aids bone health, insulin resistance, heart health, and lowers blood pressure, among many other benefits. Quality supplements are essential!
Read More
9
No withdrawal symptoms
1 people found this helpful
I adore this pure magnesium glycinate chelate! Although purchases require effort, this magnesium is worth it. It has improved my general wellbeing—no cramps, excellent sleep, no withdrawal symptoms, and overall better mood and heart stability.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Great overall health
2 people found this helpful
This brand lives up to its claims about supporting healthy bones, heart, and relieving stress. Personally, I’ve experienced improved sleep as it calms both my mind and muscles, significantly enhancing my overall health.
Read More
9
Prevents heart disease
1 people found this helpful
Critical to health, magnesium is often deficient in many people. Naturelo is known for its quality supplements. Magnesium aids bone health, insulin resistance, heart health, and lowers blood pressure, among many other benefits. Quality supplements are essential!
Read More
9
No withdrawal symptoms
1 people found this helpful
I adore this pure magnesium glycinate chelate! Although purchases require effort, this magnesium is worth it. It has improved my general wellbeing—no cramps, excellent sleep, no withdrawal symptoms, and overall better mood and heart stability.
Read More
7.5
Supports heart and sleep
Magnesium Glycinate Chelate is a remarkable product! I’ve noticed impressive results since I started using it recently. It supports my heart, nervous system, and sleep quality without causing any stomach issues, making it ideal for sensitive individuals.
Read More
7.5
Supports healthy circulation
6 people found this helpful
This premium dietary supplement provides magnesium for healthy bones, heart, nerves, and muscles. It regulates muscle contractions, relieves stress, and maintains healthy blood circulation and pressure. It also plays a role in relaxation responses vital for mood and sleep health.
Read More
Frequently Asked Questions
7.5
Supports heart and sleep
Magnesium Glycinate Chelate is a remarkable product! I’ve noticed impressive results since I started using it recently. It supports my heart, nervous system, and sleep quality without causing any stomach issues, making it ideal for sensitive individuals.
9
No withdrawal symptoms
1 people found this helpful
I adore this pure magnesium glycinate chelate! Although purchases require effort, this magnesium is worth it. It has improved my general wellbeing—no cramps, excellent sleep, no withdrawal symptoms, and overall better mood and heart stability.
2
Seek medical advice
3 people found this helpful
WARNING!! I developed AFib after a year of using this supplement. Initially, it aided my sleep, but I suspect it contributed to my Atrial Fibrillation, which I have struggled with for a year. I advise consulting a doctor before using any magnesium supplement.
9
Great overall health
2 people found this helpful
This brand lives up to its claims about supporting healthy bones, heart, and relieving stress. Personally, I’ve experienced improved sleep as it calms both my mind and muscles, significantly enhancing my overall health.
7.5
Improved relaxation quality
3 people found this helpful
This magnesium supplement, specifically Magnesium Glycinate, helps ease stress and promotes relaxation, markedly improving both my and my husband's sleep quality since we started taking it after dinner. We previously used Magnesium Citrate, but this is far superior for relaxation.
7
Eases heart palpitations
3 people found this helpful
I feel so much more at ease with this magnesium. It alleviates anxiety and tension. Moreover, it helps lower blood sugar, blood pressure, and controls heart palpitations, making it a fantastic choice for overall wellness.
7
Aids heart treatment
2 people found this helpful
In my search for a good magnesium supplement, I opted for these vitamins with chelated glycinate, which is easily assimilated. They assist in treating heart disease and diabetes due to their calming effect on the nervous system and ability to fill nutritional gaps.
9
Maintains heart health
1 people found this helpful
This is the best magnesium! Just one capsule suffices for maintenance; two or more help fill deficiencies. One capsule provides 200mg and supports healthy bones, heart, and muscles, which is crucial for preventing cramps, particularly in pregnant women.
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
8
Magnesium-rich diet linked to heart health
We examined how a magnesium-rich diet influences heart disease risk by analyzing over 15,000 adults in the Atherosclerosis Risk in Communities study.
Participants were tracked for more than 30 years, and those who enjoyed more magnesium-dense foods, like whole grains and nuts, showed a lower risk for cardiovascular and coronary heart diseases.
However, we found no significant relationship between magnesium-rich diets and ischaemic stroke incidence, indicating that the benefits might not extend to all heart-related conditions.
Participants were tracked for more than 30 years, and those who enjoyed more magnesium-dense foods, like whole grains and nuts, showed a lower risk for cardiovascular and coronary heart diseases.
However, we found no significant relationship between magnesium-rich diets and ischaemic stroke incidence, indicating that the benefits might not extend to all heart-related conditions.
References
- Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. 10.1161/JAHA.124.038870
- Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. 10.1093/ckj/sfae390
- Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. 10.6133/apjcn.202502_34(1).0010
- Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. 10.1038/s41598-025-85931-1
- Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. 10.1684/mrh.2024.0528
- Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. 10.1186/s12889-024-20785-2
- Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. 10.3390/nu16213617
- Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. 10.1371/journal.pone.0313352
- Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. 10.1038/s41598-024-74325-4
- Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. 10.4244/EIJ-D-24-00055
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. 10.1016/j.jjcc.2024.08.003
- Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. 10.1093/eurjpc/zwae251
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
- Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. 10.3390/ijerph21070932
- Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. 10.1080/00015385.2024.2379682
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0
