We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
Most Useful Reviews
9
Reduced A1C levels
5 people found this helpful
After being diagnosed with pre-diabetes and hormonal imbalances, my doctor recommended Magnesium Glycinate. I prefer the Chelate form and couldn't be more pleased with my choice. These capsules are tasteless and easy to take, with no stomach issues to report. Since I started taking them, my A1C levels have improved alongside diet changes. I highly recommend this supplement for anyone in a similar position.
Read More
9
Effective stress relief
3 people found this helpful
I absolutely love this magnesium supplement. The high quality and carefully selected ingredients provide excellent absorption without gastrointestinal issues. It relaxes me, improves my sleep, and helps reduce irritability and stress levels. The dosage and packaging are also commendable. On top of that, it contains additional plant-based magnesium, making this product stand out.
Read More
7.5
Calming effects
3 people found this helpful
I ordered this magnesium supplement due to issues with nerves, sleep, and leg cramps. Since starting it, my sleep has improved, and I feel calmer overall. I can now better ignore anxiety from outside, thanks to this product. I appreciate its effect and will continue to use it.
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
Read More
8
Magnesium reduces inflammation and syndrome
Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women.
We analyzed data from 11,686 women over 45 in the Women's Health Study to understand how magnesium intake affects inflammation and metabolic syndrome.
Our findings revealed that higher magnesium intake was linked to lower levels of C-reactive protein, a marker of inflammation.
Women with the highest magnesium consumption experienced a 27% reduced risk of metabolic syndrome compared to those with the lowest intake, particularly among those who were heavier or past smokers.
After being diagnosed with pre-diabetes and hormonal imbalances, my doctor recommended Magnesium Glycinate. I prefer the Chelate form and couldn't be more pleased with my choice. These capsules are tasteless and easy to take, with no stomach issues to report. Since I started taking them, my A1C levels have improved alongside diet changes. I highly recommend this supplement for anyone in a similar position.
Read More
9
Effective stress relief
3 people found this helpful
I absolutely love this magnesium supplement. The high quality and carefully selected ingredients provide excellent absorption without gastrointestinal issues. It relaxes me, improves my sleep, and helps reduce irritability and stress levels. The dosage and packaging are also commendable. On top of that, it contains additional plant-based magnesium, making this product stand out.
Read More
7.5
Calming effects
3 people found this helpful
I ordered this magnesium supplement due to issues with nerves, sleep, and leg cramps. Since starting it, my sleep has improved, and I feel calmer overall. I can now better ignore anxiety from outside, thanks to this product. I appreciate its effect and will continue to use it.
Read More
0
Caused digestive issues
2 people found this helpful
I didn’t like what it caused; I had diarrhoea and despite my hopes, I couldn't continue drinking it due to the side effects.
Read More
0
Not effective sleep aid
12 people found this helpful
I had high hopes for this product due to its ratings. However, from the first night, my intermittent sleep turned into constant wakefulness. I found myself in bed from three in the morning until midday, feeling nauseous and experiencing a strange pulse throughout my body. After five nights of this, my mood plummeted, and I felt overwhelmed. I later learned that the formula had changed, adding rice flour and magnesium oxide, resulting in inadequate magnesium levels and digestive issues. Unfortunately, this product will be going in the bin, and I feel let down.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium plays a crucial role in various bodily functions, including regulating cholesterol levels, but its direct impact on high cholesterol levels is still a topic of ongoing research. Some studies suggest that maintaining adequate magnesium levels can help improve lipid profiles by reducing LDL (bad cholesterol) and increasing HDL (good cholesterol). This mineral is known to have anti-inflammatory properties, which could indirectly benefit heart health and cholesterol levels by improving overall cardiovascular function.
However, it's important to note that while magnesium can be a supportive element in a holistic approach to managing cholesterol, it should not be viewed as a standalone solution. Incorporating magnesium-rich foods, such as leafy greens, nuts, seeds, and whole grains, into a balanced diet is advisable. Moreover, those with high cholesterol should consult healthcare professionals for personalized advice and appropriate treatment options, including lifestyle changes and medications when necessary.
Research does suggest that magnesium might be beneficial in managing high cholesterol levels, though the evidence is mixed. A study on deep seawater (DSW), which is rich in magnesium, indicated that participants who consumed it daily experienced a significant reduction in total cholesterol and LDL cholesterol, alongside reduced oxidative stress markers [5]. This aligns with findings that higher magnesium intake is linked to lower cholesterol levels and cardiovascular risk factors, as shown in a diverse group of participants [3].
However, the relationship between magnesium and cholesterol isn’t universally established across all studies. For instance, while magnesium chloride demonstrated potential in reducing cholesterol and atherosclerosis in animal studies, results varied, showing some promise but not definitive conclusions [8]. Additionally, a study involving meat products enriched with plant sterols and magnesium found that while plant sterols were effective, magnesium alone did not show a significant effect on cholesterol levels [7]. Overall, while certain studies reveal encouraging correlations between magnesium and cholesterol management, further research is required to definitively establish its efficacy for high cholesterol in humans.
Based on user reviews, many individuals have reported significant improvements in various symptoms after incorporating Magnesium Glycinate into their routine. For instance, one user shared that after adjusting their diet in conjunction with taking this supplement, their A1C levels saw improvement, which is particularly notable for those dealing with pre-diabetes and hormonal issues Read Review. Additionally, others have highlighted benefits such as enhanced sleep quality, reduced anxiety, and overall feeling calmer, indicating a soothing effect on both sleep and general well-being Read Review, Read Review.
However, experiences with this supplement can vary dramatically. Some users reported gastrointestinal issues or negative effects like constant wakefulness, emphasizing that while many find relief, others may face challenges with this product Read ReviewRead Review. It’s worth noting that a user recognized a meaningful impact on lowering blood pressure through magnesium supplementation, showcasing its potential benefits for cardiovascular health too Read Review. Therefore, individual results can vary, and potential users should consider these diverse experiences.
9
Reduced A1C levels
5 people found this helpful
After being diagnosed with pre-diabetes and hormonal imbalances, my doctor recommended Magnesium Glycinate. I prefer the Chelate form and couldn't be more pleased with my choice. These capsules are tasteless and easy to take, with no stomach issues to report. Since I started taking them, my A1C levels have improved alongside diet changes. I highly recommend this supplement for anyone in a similar position.
7.5
Calming effects
3 people found this helpful
I ordered this magnesium supplement due to issues with nerves, sleep, and leg cramps. Since starting it, my sleep has improved, and I feel calmer overall. I can now better ignore anxiety from outside, thanks to this product. I appreciate its effect and will continue to use it.
7.5
Improved sleep quality
1 people found this helpful
Mumtaz I use it after experiencing sleep difficulties. I take it with my last meal half an hour before bed, accompanied by a full glass of water as instructed. It has positively impacted my sleep quality. Even if I only sleep for three hours, I wake feeling refreshed. The tremors in my limbs have ceased. I’m uncertain if this product is the sole cause, but it likely contributes to the improvement. Update: This is my second order. The quantity is impressive, the quality is excellent, and the effects are noticeable.
0
Caused digestive issues
2 people found this helpful
I didn’t like what it caused; I had diarrhoea and despite my hopes, I couldn't continue drinking it due to the side effects.
0
Not effective sleep aid
12 people found this helpful
I had high hopes for this product due to its ratings. However, from the first night, my intermittent sleep turned into constant wakefulness. I found myself in bed from three in the morning until midday, feeling nauseous and experiencing a strange pulse throughout my body. After five nights of this, my mood plummeted, and I felt overwhelmed. I later learned that the formula had changed, adding rice flour and magnesium oxide, resulting in inadequate magnesium levels and digestive issues. Unfortunately, this product will be going in the bin, and I feel let down.
4
Stabilised blood pressure
1 people found this helpful
I noticed some effect on lowering blood pressure. I learned from YouTube that high blood pressure might be linked to magnesium deficiency, so I decided to give it a try. Previously, I was on the verge of high blood pressure, but now it has stabilised around 130, which is quite pleasing!
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
8
Magnesium chloride may lower cholesterol
Atherogenesis inhibition induced by magnesium-chloride fortification of drinking water.
We explored whether magnesium, specifically in the form of magnesium chloride, could help fight high cholesterol and atherosclerosis.
In a study with male mice, different concentrations of magnesium chloride were added to their drinking water, while they followed various diets.
We found that the higher concentration seemed to lower the extent of atherosclerosis significantly, along with reducing cholesterol levels after an initial stage.
However, overall blood lipid levels remained similar before and after the study, indicating mixed results in magnesium's effectiveness against high cholesterol.
7
Plant sterols lower cholesterol effectively
The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure.
We investigated how meat products enriched with plant sterols and minerals, particularly magnesium, influence cholesterol levels. In a thorough study involving 21 participants, we compared these enriched products against regular ones in a controlled setting.
While the higher dose of plant sterols reduced total cholesterol levels significantly, the lower dose did not yield the same benefit. We also noted that factors such as blood pressure and other lipid levels remained unchanged throughout the study.
Overall, it seems that higher doses of plant sterols are beneficial for those with mildly to moderately high cholesterol, but magnesium alone didn't show a significant effect.
References
Mohammed KA, Goji ADT, Tanko Y, Muhammed A, Salisu IA. Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats. Niger J Physiol Sci. 2019;34:149.
Lupo MG, Biancorosso N, Brilli E, Tarantino G, Adorni MP, et al. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line. Nutrients. 2020;12. doi:10.3390/nu12020436
Yamori Y, Sagara M, Mizushima S, Liu L, Ikeda K, et al. An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations. Hypertens Res. 2015;38:219. doi:10.1038/hr.2014.158
Sheu MJ, Chou PY, Lin WH, Pan CH, Chien YC, et al. Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study. Mar Drugs. 2013;11:2183. doi:10.3390/md11062183
Fu ZY, Yang FL, Hsu HW, Lu YF. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012;15:535. doi:10.1089/jmf.2011.2007
Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, et al. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005;28:1438.
Tapola NS, Lyyra ML, Karvonen HM, Uusitupa MI, Sarkkinen ES. The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure. Int J Food Sci Nutr. 2004;55:389.
Cohen H, Sherer Y, Shaish A, Shoenfeld Y, Levkovitz H, et al. Atherogenesis inhibition induced by magnesium-chloride fortification of drinking water. Biol Trace Elem Res. 2002;90:251.
Evans DA, Tariq M, Sujata B, McCann G, Sobki S. The effects of magnesium sulphate and EDTA in the hypercholesterolaemic rabbit. Diabetes Obes Metab. 2001;3:417.