Calcium (as Calcium Carbonate and Calcium Gluconate)
1,000 mg
77%
Magnesium (as Magnesium Oxide and Magnesium Gluconate)
400 mg
95%
Zinc (as Zinc Gluconate and Zinc Citrate)
25 mg
227%
Sodium
10 mg
<1%
Top Medical Research Studies
9.5
Vitamin D3 aids autoimmune thyroiditis
Supplementation with active vitamin D3 ameliorates experimental autoimmune thyroiditis in mice by modulating the differentiation and functionality of intrathyroidal T-cell subsets.
We observed that vitamin D3 supplementation may play a significant role in managing autoimmune thyroiditis, a condition often marked by thyroid inflammation. In this study, researchers induced autoimmune thyroiditis in female mice and administered vitamin D3 to evaluate its effects on the disease.
After eight weeks of treatment, the results showed a notable reduction in thyroid damage and lower levels of thyroid autoantibodies in the mice receiving vitamin D3. Specifically, the vitamin appeared to inhibit the activity of certain inflammatory immune cells, which are typically elevated in autoimmune conditions. At the same time, it seemed to support the activity of regulatory immune cells that help keep inflammation in check.
This study highlights the potential of vitamin D3 as a therapeutic option to mitigate the effects of autoimmune thyroiditis, suggesting that it could help balance the immune response in affected individuals. As researchers continue to delve into the role of vitamin D in autoimmune disorders, findings like these support the notion that maintaining adequate vitamin D levels might be crucial for immune health.
Read More
9
Magnesium shows promise for RA treatment
Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways.
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Read More
9
Magnesium may reduce lupus severity
Revised version with tracked changes oral Magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus.
We investigated how magnesium (Mg) affects the severity of autoimmune lupus in mice. By feeding MRL/lpr female mice a standard or high magnesium diet for nine weeks, we measured impacts on skin lesions and pathogenic autoantibodies.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
Read More
Most Useful Reviews
9
Fertility improvement
6 people found this helpful
I purchased this for fertility due to my polycystic ovaries. I’m taking multiple iHerb supplements, and after my second child at 45, I believe this product is essential. I'm still ovulating monthly, free from menopausal disorders, so I highly recommend it for treating autoimmune disorder symptoms.
Read More
9
Reduced pain
3 people found this helpful
I suffered from vertebra pain for six months. I ordered this supplement as a hopeful measure. Taking it once a day at night, I found my pain completely alleviated, demonstrating its effectiveness against my autoimmune disorder.
Read More
9
Reduced anxiety
2 people found this helpful
I purchased this to alleviate inflammation and reduce anxiety related to my autoimmune disorder. After a month at two capsules daily, my anxiety and nervousness disappeared, leading to a much calmer state. I recommend this to friends; it works!
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
9.5
Vitamin D3 aids autoimmune thyroiditis
Supplementation with active vitamin D3 ameliorates experimental autoimmune thyroiditis in mice by modulating the differentiation and functionality of intrathyroidal T-cell subsets.
We observed that vitamin D3 supplementation may play a significant role in managing autoimmune thyroiditis, a condition often marked by thyroid inflammation. In this study, researchers induced autoimmune thyroiditis in female mice and administered vitamin D3 to evaluate its effects on the disease.
After eight weeks of treatment, the results showed a notable reduction in thyroid damage and lower levels of thyroid autoantibodies in the mice receiving vitamin D3. Specifically, the vitamin appeared to inhibit the activity of certain inflammatory immune cells, which are typically elevated in autoimmune conditions. At the same time, it seemed to support the activity of regulatory immune cells that help keep inflammation in check.
This study highlights the potential of vitamin D3 as a therapeutic option to mitigate the effects of autoimmune thyroiditis, suggesting that it could help balance the immune response in affected individuals. As researchers continue to delve into the role of vitamin D in autoimmune disorders, findings like these support the notion that maintaining adequate vitamin D levels might be crucial for immune health.
Read More
9
Magnesium shows promise for RA treatment
Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways.
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Read More
9
Magnesium may reduce lupus severity
Revised version with tracked changes oral Magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus.
We investigated how magnesium (Mg) affects the severity of autoimmune lupus in mice. By feeding MRL/lpr female mice a standard or high magnesium diet for nine weeks, we measured impacts on skin lesions and pathogenic autoantibodies.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
Read More
9
Magnesium-based therapy for RA
Anti-Acidification and Immune Regulation by Nano-Ceria-Loaded Mg-Al Layered Double Hydroxide for Rheumatoid Arthritis Therapy.
We explored the potential of a new magnesium-aluminum layered double hydroxide combined with nano-ceria in treating rheumatoid arthritis (RA). This innovative therapy targets the unhealthy immune environment and the harmful buildup of hydrogen ions associated with RA. By neutralizing excess acidity, we observed improved immune responses, encouraging the body to heal damaged bones. This approach showed promising results in mice models, indicating it may be a viable future treatment for managing RA effectively.
I purchased this for fertility due to my polycystic ovaries. I’m taking multiple iHerb supplements, and after my second child at 45, I believe this product is essential. I'm still ovulating monthly, free from menopausal disorders, so I highly recommend it for treating autoimmune disorder symptoms.
Read More
9
Reduced pain
3 people found this helpful
I suffered from vertebra pain for six months. I ordered this supplement as a hopeful measure. Taking it once a day at night, I found my pain completely alleviated, demonstrating its effectiveness against my autoimmune disorder.
Read More
9
Reduced anxiety
2 people found this helpful
I purchased this to alleviate inflammation and reduce anxiety related to my autoimmune disorder. After a month at two capsules daily, my anxiety and nervousness disappeared, leading to a much calmer state. I recommend this to friends; it works!
Read More
9
Enhanced strength
2 people found this helpful
These pills feel magical. I have discs and varicose veins, but after taking these capsules, my energy has returned every night post-meal. They have greatly helped me manage my autoimmune disorder effectively.
Read More
9
Healthy skin
100 people found this helpful
After three months of this magnesium complex, I noticed clearer skin, stronger hair, and less issue with my teeth, though I didn’t see improvements in my nails.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Based on user reviews, the time it takes to see results from this supplement for managing autoimmune disorders can vary significantly. Many users report noticeable improvements within a month of consistent use. For instance, one user indicated that after taking two capsules daily for a month, their anxiety and nervousness related to their autoimmune disorder disappeared Read Review. Another user mentioned experiencing reduced joint pain and improved sleep after approximately a month on the supplement Read Review.
However, some users have seen results even sooner. One individual noted improved sleep and an emotional state enhancement within just a week of use Read Review. Conversely, while immediate benefits are reported, some have indicated that more substantial changes might take a few weeks or even months, highlighting the individualized nature of how supplements affect people with autoimmune conditions. Overall, a general consensus among users suggests that one can expect to start noticing changes typically between one to three months.
Based on scientific research, supplements like calcium and vitamin D show potential benefits for individuals with autoimmune disorders. A study on calcium nanosheets highlighted their unique ability to address inflammation and promote bone repair in conditions such as rheumatoid arthritis (RA), suggesting a promising therapeutic avenue for managing autoimmune conditions ([1]). Furthermore, vitamin D has been extensively investigated for its role in various autoimmune disorders, including thyroiditis and myopathies. Research indicates that vitamin D3 supplementation reduced thyroid damage and autoantibody levels in autoimmune thyroiditis models ([3]), and it also positively impacted muscle health in patients with inflammatory myopathies, signaling a correlation between vitamin D levels and improved disease outcomes ([2]).
Moreover, studies show that optimizing vitamin D levels could be beneficial for diseases like Graves' disease and alopecia areata, where sufficient levels are linked to better management of symptoms and disease progression ([4], [8]). However, while evidence suggests certain nutrients like vitamin D can play a supportive role in immune regulation and inflammation reduction in autoimmune disorders, ongoing research is essential to fully establish their efficacy and treatment protocols. Thus, these findings imply that supplementation, particularly with vitamin D and calcium, may serve as an adjunct therapy in managing autoimmune conditions, but should be approached with professional guidance and further clinical validation.
Based on user reviews, many individuals have reported various improvements in their symptoms related to autoimmune disorders after using this supplement. Users frequently mention enhanced overall well-being, with specific improvements noted in sleep quality, anxiety reduction, and pain alleviation. For example, one user experiencing vertebra pain reported complete relief after taking the supplement nightly Read Review, while another claimed their anxiety disappeared after a month of daily use, leading to a calmer state Read Review.
Others have shared similar experiences, citing benefits such as reduced joint pain, increased energy, and even cosmetic improvements like healthier hair and skin Read Review. Users have also mentioned that the supplement has contributed to better emotional states, with one individual reporting improved sleep and mood after just a week of use Read Review. While individual results can vary, the collective feedback indicates that many people have found this supplement effective in managing symptoms of their autoimmune disorders.
Users report a variety of experiences when combining this supplement with other supplements to address autoimmune disorders. Many have shared success stories, stating that the combination has significantly improved their overall well-being. For instance, one user noted that after taking the supplement alongside additional vitamins, they experienced remarkable relief from vertebra pain attributed to their autoimmune condition Read Review. Another user highlighted that with the addition of vitamin D while using this supplement, they found enhanced emotional stability and improved skin health, which they linked to better management of their autoimmune symptoms Read Review.
However, not all feedback was positive when it came to supplementation. Some users experienced side effects or limited results when using this product, especially if combined with certain other vitamins. One user expressed dissatisfaction with a different formulation that contained specific mineral forms deemed ineffective for treating autoimmune disorders Read Review. Overall, while many users advocate for the effectiveness of this supplement when used in conjunction with others, individual responses can vary based on personal health needs and supplement formulations.
Users have shared varied experiences regarding the right dose for Calcium in managing autoimmune disorders. Some recommend higher daily doses, such as taking one capsule three times daily as indicated by a user who noted significant improvements in overall condition and energy levels after following this regimen Read Review. Another user experienced positive results from a combination of Calcium, Magnesium, Zinc, and Vitamin D3, stating that regular intake improved their nails and overall well-being, highlighting the importance of adherence to a consistent dosage Read Review.
9
Reduced anxiety
2 people found this helpful
I purchased this to alleviate inflammation and reduce anxiety related to my autoimmune disorder. After a month at two capsules daily, my anxiety and nervousness disappeared, leading to a much calmer state. I recommend this to friends; it works!
4
Less joint pain
3 people found this helpful
With osteoarthritis in my joints, my doctor prescribed expensive vitamins. After switching to these from iHerb, I've noticed less joint pain and improved sleep after a month. They are effective for my autoimmune disorder and have enhanced the appearance of my skin, hair, and nails.
9
Better sleep
1 people found this helpful
Excellent! following stress and sleep disturbances, I ordered this magnesium complex. After a week, I found better sleep and an improved emotional state, with my skin also benefiting.
9
Reduced pain
3 people found this helpful
I suffered from vertebra pain for six months. I ordered this supplement as a hopeful measure. Taking it once a day at night, I found my pain completely alleviated, demonstrating its effectiveness against my autoimmune disorder.
9
Improved sleep quality
Perfect! I bought it for my mother for prevention, and she felt a difference by the second day. Her sleep has improved, anxieties have lessened, and her hair is falling out less. I encouraged my sister to buy another bottle. I didn't expect such results for the price. I also take D3 because the daily dose here isn't sufficient for treating autoimmune disorder. If this review helps, I'm glad. Wishing all good health!
0
Not effective treatment
3 people found this helpful
I do not recommend this. I ordered it for a friend without checking the composition, which turned out to contain solid oxides and gluconates. These forms of minerals are ineffective for treating autoimmune disorder.
7.5
Improved condition
2 people found this helpful
This complex was recommended by my doctor. After taking one capsule three times daily, I've noticed significant improvements in my overall condition and energy levels in managing my autoimmune disorder.
8.5
Health improvement
2 people found this helpful
I order Calcium, Magnesium, Zinc + D3 regularly. After a month, I noticed my nails grew stronger and overall well-being improved. These were crucial in managing my autoimmune disorder, which allows me to stay active at 60.
9.5
Calcium's role in RA treatment
Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis.
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
9.5
Vitamin D3 aids autoimmune thyroiditis
Supplementation with active vitamin D3 ameliorates experimental autoimmune thyroiditis in mice by modulating the differentiation and functionality of intrathyroidal T-cell subsets.
We observed that vitamin D3 supplementation may play a significant role in managing autoimmune thyroiditis, a condition often marked by thyroid inflammation. In this study, researchers induced autoimmune thyroiditis in female mice and administered vitamin D3 to evaluate its effects on the disease.
After eight weeks of treatment, the results showed a notable reduction in thyroid damage and lower levels of thyroid autoantibodies in the mice receiving vitamin D3. Specifically, the vitamin appeared to inhibit the activity of certain inflammatory immune cells, which are typically elevated in autoimmune conditions. At the same time, it seemed to support the activity of regulatory immune cells that help keep inflammation in check.
This study highlights the potential of vitamin D3 as a therapeutic option to mitigate the effects of autoimmune thyroiditis, suggesting that it could help balance the immune response in affected individuals. As researchers continue to delve into the role of vitamin D in autoimmune disorders, findings like these support the notion that maintaining adequate vitamin D levels might be crucial for immune health.
7
Vitamin D's role in muscle health
Vitamin D and its receptor in skeletal muscle are associated with muscle disease manifestation, lipid metabolism and physical fitness of patients with myositis.
We explored the connection between vitamin D levels and muscle health in patients with idiopathic inflammatory myopathies (IIM), a type of autoimmune disorder. The study included 46 IIM patients and 67 healthy individuals, assessing both groups to understand how vitamin D and its receptor (VDR) relate to disease symptoms, physical fitness, and lipid metabolism.
Through muscle biopsies and blood tests, we measured the vitamin D levels and gene expressions related to its metabolism. We found that lower levels of biologically active vitamin D in IIM patients suggest their bodies may not be effectively processing this vital nutrient. Moreover, regular exercise seemed to improve vitamin D levels, VDR expression, and linked muscle function with overall health outcomes for these patients.
Our findings emphasize the importance of vitamin D in managing muscle health and its potential role in enhancing physical fitness among individuals with autoimmune conditions. While the study presents promising insights, it is clear that ongoing research is needed to fully understand the relationship between vitamin D, muscle function, and autoimmune disorders.
8
Vitamin D aids Graves' disease therapy
A beneficial levels of 25-hydroxyvitamin D for a decrease in thyrotropin receptor antibody (TRAB) in patients with Graves' disease: a real-world study.
We explored the connection between vitamin D levels and the management of Graves' disease, an autoimmune disorder characterized by overactive thyroid function. Through our research with 171 patients, we aimed to see if pre-treatment levels of 25-hydroxyvitamin D could influence the reduction of thyrotropin receptor antibodies (TRAB) during treatment.
Our study divided patients into three groups based on their vitamin D levels: less than 20 ng/mL, between 20-29 ng/mL, and 30 ng/mL or more. The findings were quite revealing. We observed that patients with vitamin D levels ranging from 20 to 29 ng/mL experienced significantly higher rates of TRAB remission and negative conversion compared to the other groups during follow-ups at 6, 12, and 24 months.
This suggests that maintaining vitamin D within this specific range can be beneficial for patients newly diagnosed with Graves' disease as they undergo antithyroid treatment. However, we noted that vitamin D levels did not seem to affect the normalization of free triiodothyronine and free thyroxine levels over time.
In summary, our findings emphasize the potential role of adequate vitamin D levels in supporting immune regulation and therapeutic outcomes in autoimmune disorders, particularly Graves' disease.
8
Vitamin D linked to alopecia areata
Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.
Our investigation focused on the role of vitamin D in the autoimmune disorder known as alopecia areata (AA). We delved into data from various studies, including a meta-analysis of 34 papers covering nearly 5,000 participants from multiple countries.
The findings demonstrated a clear association between low vitamin D levels and increased risk of AA. Specifically, patients with alopecia areata exhibited significantly lower serum vitamin D levels compared to healthy individuals. In fact, those with vitamin D deficiency were found to be at a higher risk of developing the condition.
These results suggest that vitamin D supplementation could potentially serve as an effective treatment strategy for individuals suffering from AA. However, it’s important to note that while vitamin D showed promise, the study did not find significant differences in other trace elements, such as copper, in relation to AA.
Overall, our research underscores the importance of maintaining adequate vitamin D levels, as it may play a crucial role in the management of autoimmune disorders like alopecia areata.
References
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Vernerová L, Vokurková M, Laiferová NA, Nemec M, Špiritović M, et al. Vitamin D and its receptor in skeletal muscle are associated with muscle disease manifestation, lipid metabolism and physical fitness of patients with myositis. Arthritis Res Ther. 2025;27:48. 10.1186/s13075-025-03516-9
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Chen X, Zhang Y, Lin L, Chen Y, Shen X, et al. A beneficial levels of 25-hydroxyvitamin D for a decrease in thyrotropin receptor antibody (TRAB) in patients with Graves' disease: a real-world study. BMC Endocr Disord. 2025;25:14. 10.1186/s12902-024-01823-x
Rafati A, Ramezani R, Esmaeili Gouvarchin Ghaleh H, Bahrami S, Alvanegh AG, et al. Calcitriol Treated Mesenchymal Stem Cells Modulated Immune Response in Collagen-Induced Rheumatoid Arthritis in BALB/c Mice. Transplant Proc. 2025;57:355. 10.1016/j.transproceed.2024.12.020
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Hijjawi N, Tout FS, Azaizeh B, Aljaafreh B. The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. Clin Rheumatol. 2025;44:591. 10.1007/s10067-024-07285-9
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Verlato A, Laragione T, Bin S, Kim RH, Salem F, et al. Revised version with tracked changes oral Magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus. BMC Immunol. 2024;25:58. 10.1186/s12865-024-00650-y
Liu H, Zhang K, Xiong L. Dietary magnesium intake and rheumatoid arthritis patients' all-cause mortality: evidence from the NHANES database. J Health Popul Nutr. 2024;43:112. 10.1186/s41043-024-00597-1
Fu H, Guo Y, Fang W, Wang J, Hu P, et al. Anti-Acidification and Immune Regulation by Nano-Ceria-Loaded Mg-Al Layered Double Hydroxide for Rheumatoid Arthritis Therapy. Adv Sci (Weinh). 2024;11:e2307094. 10.1002/advs.202307094
Fang J, Cao T, Liu C, Wang D, Zhang H, et al. Association between magnesium, copper, and potassium intakes with risk of rheumatoid arthritis: a cross-sectional study from National Health and Nutrition Examination Survey (NHANES). BMC Public Health. 2023;23:2085. 10.1186/s12889-023-16906-y
Laragione T, Harris C, Azizgolshani N, Beeton C, Bongers G, et al. Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome. EBioMedicine. 2023;92:104603. 10.1016/j.ebiom.2023.104603
Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. 10.1186/s12974-023-02696-y
Shao Y, Mu Q, Wang R, Luo H, Song Z, et al. SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease. Sci China Life Sci. 2025. 10.1007/s11427-024-2817-y
Chen L, Yan C, Huang C, Jiang Z, Lin R, et al. Higher dietary zinc intake increases the risk of autoimmune thyroiditis. Postgrad Med J. 2025. 10.1093/postmj/qgae202
Bayiroglu AF, Acar G, Gulbahce-Mutlu E, Baltaci SB, Mogulkoc R, et al. Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model. J Trace Elem Med Biol. 2024;86:127540. 10.1016/j.jtemb.2024.127540
Fang D, Jiang D, Shi G, Song Y. The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2024;25:710. 10.1186/s12891-024-07768-5
Cheng J, Rink L, Wessels I. Zinc Supplementation Reduces the Formation of Neutrophil Extracellular Traps by Decreasing the Expression of Peptidyl Arginine Deiminase 4. Mol Nutr Food Res. 2024;68:e2400013. 10.1002/mnfr.202400013