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SCIENTIFIC SCORE
Questionable
Based on 10 Researches
6.6
USERS' SCORE
Medium or Average
Based on 13 Reviews
6.1
Supplement Facts
Serving Size: 3 Caplets
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
15 mcg (600 IU)
75%
Calcium (as Calcium Carbonate and Calcium Gluconate)
1,000 mg
77%
Magnesium (as Magnesium Oxide and Magnesium Gluconate)
400 mg
95%
Zinc (as Zinc Gluconate and Zinc Citrate)
25 mg
227%
Sodium
10 mg
<1%
Top Medical Research Studies
8
Vitamin D and nausea in gastroparesis
Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity.
Strong link but unclear benefits.
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
8
Magnesium effectively reduces PONV
Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial.
Moderate relevance due to context
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
7
Zinc treatment reduces nausea risk
Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.
Moderate relevance to nausea aspect
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.
Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
Most Useful Reviews
9.5
Nausea relief observed
Very pleased with the fast delivery, high-quality, and convenient packaging. The capsules are large but swallow easily, tasting of citrus. I've noticed improvements like increased energy and a stopped headache after just ten days of taking one capsule daily. They have positively impacted my mood and fitness routine. Omega-3 is excellent for those concerned with diet and replenishing the body's deficiencies.
Read More
9.5
Nausea alleviated
The packaging is convenient, and the quality of the ingredients is clear. Previously, I struggled with pure zinc supplements due to nausea, but this manufacturer’s product has resolved that issue for me completely.
Read More
9.5
Effective without nausea
This product does not cause nausea, and the composition is good. I will be buying it again.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 10 Researches
6.6
9
Low opioids improve postoperative comfort
Are There Any Advantages of the Low Opioid Anaesthesia and Non-Opioid Postoperative Analgesia Protocol: A Clinical Observational Study.
Magnesium's impact on nausea unclear
We explored the effects of a low-opioid anesthesia (LOA) protocol during laparoscopic cholecystectomy and its impact on nausea, vomiting, and pain control. In our study, we compared 40 patients who received LOA, which included magnesium sulfate, with another 40 patients who were given standard opioid-based anesthesia.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
Read More
8
Vitamin D and nausea in gastroparesis
Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity.
Strong link but unclear benefits.
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
8
Magnesium effectively reduces PONV
Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial.
Moderate relevance due to context
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
7
Magnesium's role in nausea unclear
Analgesic Effects of Preoperative Combination of Oral Pregabalin and Intravenous Magnesium Sulfate on Postoperative Pain in Patients Undergoing Posterolateral Spinal Fusion Surgery: A 4-arm, Randomized, Double-blind, Placebo-controlled Trial.
Not definitive for nausea relief
We conducted a thorough investigation into how combining oral pregabalin and intravenous magnesium sulfate influences nausea in patients undergoing a specific type of spine surgery. In a well-structured trial, 104 participants were randomly assigned to one of four groups, where some received magnesium sulfate with pregabalin, while others received either a placebo or just one of the drugs.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Read More
7
Magnesium reduces post-operative nausea
Comparison of intravenous injection of magnesium sulfate and lidocaine effectiveness on the prevention of laryngospasm and analgesic requirement in tonsillectomy.
Consideration of magnesium's effects
In our exploration of how magnesium treatment influences nausea, we conducted a double-blind clinical trial with 62 children undergoing tonsillectomy. Participants were divided into two groups, where one received magnesium sulfate and the other lidocaine shortly after intubation.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 13 Reviews
6.1
9.5
Nausea relief observed
Very pleased with the fast delivery, high-quality, and convenient packaging. The capsules are large but swallow easily, tasting of citrus. I've noticed improvements like increased energy and a stopped headache after just ten days of taking one capsule daily. They have positively impacted my mood and fitness routine. Omega-3 is excellent for those concerned with diet and replenishing the body's deficiencies.
Read More
9.5
Nausea alleviated
The packaging is convenient, and the quality of the ingredients is clear. Previously, I struggled with pure zinc supplements due to nausea, but this manufacturer’s product has resolved that issue for me completely.
9.5
Effective without nausea
This product does not cause nausea, and the composition is good. I will be buying it again.
8.8
Nausea not experienced
I purchased the calcium-magnesium-zinc complex for preventative health due to a calcium deficiency. Although the tablets are large, I had no trouble swallowing. After two months, my hair has grown faster, and my nails are breaking less. Importantly, I did not experience nausea or side effects from using this product.
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8.3
Nausea absent with use
I chose this product for its beneficial ingredients, and I have had no nausea taking the zinc daily. Since I began the supplement, my nails have stopped chipping, and hair growth has increased significantly.
