SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Saturated Fat
0.5 g
3%**
Cholesterol
10 mg
3%
Fish Oilprovides 360 mg of Total Omega-3 Fatty Acids†comprising of:EPA (Eicosapentaenoic Acid)DHA (Docosahexaenoic Acid)Other Fatty Acids
1,200 mg (1.2 g)
***************
Top Medical Research Studies
9
Eicosapentaenoic acid alleviates back pain
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Strong relevance to back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
9
Eicosapentaenoic acid aids pain relief
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Study directly assesses EPA's effects
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) could relieve chronic low-back and knee pain in adults. The study was carefully structured as a randomized, double-blind, placebo-controlled trial, which helps ensure that the findings are reliable and unbiased.
Our participants, totaling 120 adults who had been suffering from pain in their low back and knees for at least three months, were divided into two groups. One group received a daily dose of 594 mg of l-serine combined with 149 mg of EPA, while the other group received a placebo. Over the course of eight weeks, we tracked their progress using various pain measurement tools.
The results were promising, showing that both l-serine and EPA together led to meaningful reductions in pain scores. This suggests that including EPA in treatment plans could be beneficial for those suffering from persistent low-back pain.
Our trial highlighted the importance of this combination in pain relief, particularly for chronic conditions. The findings from this study hold potential for guiding future treatments aimed at enhancing the quality of life for many suffering from chronic pain.
Our participants, totaling 120 adults who had been suffering from pain in their low back and knees for at least three months, were divided into two groups. One group received a daily dose of 594 mg of l-serine combined with 149 mg of EPA, while the other group received a placebo. Over the course of eight weeks, we tracked their progress using various pain measurement tools.
The results were promising, showing that both l-serine and EPA together led to meaningful reductions in pain scores. This suggests that including EPA in treatment plans could be beneficial for those suffering from persistent low-back pain.
Our trial highlighted the importance of this combination in pain relief, particularly for chronic conditions. The findings from this study hold potential for guiding future treatments aimed at enhancing the quality of life for many suffering from chronic pain.
Read More
9
EPA may protect discs from degeneration
Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.
High relevance to treatment effectiveness
We aimed to explore how eicosapentaenoic acid (EPA), an omega-3 fatty acid, can impact intervertebral disc degeneration, which is a common cause of lower back pain. In the study, we used Sprague Dawley rats that had their lumbar discs punctured to induce degeneration. After the surgery, the rats were split into two groups: one received a daily diet enriched with EPA and docosahexaenoic acid (DHA), while the other group followed a standard diet.
After a month of the omega-3 supplementation, we noticed a significant drop in specific blood markers indicating inflammation. By the end of the two-month period, advanced imaging techniques and tissue analysis revealed that the rats on the omega-3 diet had maintained better hydration and displayed less damage to their intervertebral discs compared to the control group.
These findings suggest that incorporating eicosapentaenoic acid into the diet could reduce the inflammation linked to disc degeneration, potentially offering a protective effect against the progression of back pain. This research opens pathways to exploring omega-3s as a viable treatment option for people suffering from chronic back issues.
After a month of the omega-3 supplementation, we noticed a significant drop in specific blood markers indicating inflammation. By the end of the two-month period, advanced imaging techniques and tissue analysis revealed that the rats on the omega-3 diet had maintained better hydration and displayed less damage to their intervertebral discs compared to the control group.
These findings suggest that incorporating eicosapentaenoic acid into the diet could reduce the inflammation linked to disc degeneration, potentially offering a protective effect against the progression of back pain. This research opens pathways to exploring omega-3s as a viable treatment option for people suffering from chronic back issues.
Read More
Most Useful Reviews
10
No leg pain
These softgels are fantastic and do the job well. I used to suffer from pain in my legs, but since taking this fish oil, I no longer experience any pain. I can now bend down to clean the cat litter with ease. I wouldn't go back to the 1200mg fish oil as it caused my legs to hurt again.
Read More
8.8
Eliminated back pain
Triple Strength is remarkable. I often hear complaints about fish oil capsules tasting too fishy, but these are splendid. They seem to have alleviated my back muscle pain. Additionally, I take them for my high triglycerides.
Read More
8.8
Less pain
Bought at a significant discount and very pleased with the quality and quantity. I've been taking three tablets daily for four months, and I recommend them. They have noticeably improved my health and reduced my back pain.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
- All Researches
9
Eicosapentaenoic acid alleviates back pain
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Strong relevance to back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
9
Eicosapentaenoic acid aids pain relief
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Study directly assesses EPA's effects
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) could relieve chronic low-back and knee pain in adults. The study was carefully structured as a randomized, double-blind, placebo-controlled trial, which helps ensure that the findings are reliable and unbiased.
Our participants, totaling 120 adults who had been suffering from pain in their low back and knees for at least three months, were divided into two groups. One group received a daily dose of 594 mg of l-serine combined with 149 mg of EPA, while the other group received a placebo. Over the course of eight weeks, we tracked their progress using various pain measurement tools.
The results were promising, showing that both l-serine and EPA together led to meaningful reductions in pain scores. This suggests that including EPA in treatment plans could be beneficial for those suffering from persistent low-back pain.
Our trial highlighted the importance of this combination in pain relief, particularly for chronic conditions. The findings from this study hold potential for guiding future treatments aimed at enhancing the quality of life for many suffering from chronic pain.
Our participants, totaling 120 adults who had been suffering from pain in their low back and knees for at least three months, were divided into two groups. One group received a daily dose of 594 mg of l-serine combined with 149 mg of EPA, while the other group received a placebo. Over the course of eight weeks, we tracked their progress using various pain measurement tools.
The results were promising, showing that both l-serine and EPA together led to meaningful reductions in pain scores. This suggests that including EPA in treatment plans could be beneficial for those suffering from persistent low-back pain.
Our trial highlighted the importance of this combination in pain relief, particularly for chronic conditions. The findings from this study hold potential for guiding future treatments aimed at enhancing the quality of life for many suffering from chronic pain.
Read More
9
EPA may protect discs from degeneration
Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.
High relevance to treatment effectiveness
We aimed to explore how eicosapentaenoic acid (EPA), an omega-3 fatty acid, can impact intervertebral disc degeneration, which is a common cause of lower back pain. In the study, we used Sprague Dawley rats that had their lumbar discs punctured to induce degeneration. After the surgery, the rats were split into two groups: one received a daily diet enriched with EPA and docosahexaenoic acid (DHA), while the other group followed a standard diet.
After a month of the omega-3 supplementation, we noticed a significant drop in specific blood markers indicating inflammation. By the end of the two-month period, advanced imaging techniques and tissue analysis revealed that the rats on the omega-3 diet had maintained better hydration and displayed less damage to their intervertebral discs compared to the control group.
These findings suggest that incorporating eicosapentaenoic acid into the diet could reduce the inflammation linked to disc degeneration, potentially offering a protective effect against the progression of back pain. This research opens pathways to exploring omega-3s as a viable treatment option for people suffering from chronic back issues.
After a month of the omega-3 supplementation, we noticed a significant drop in specific blood markers indicating inflammation. By the end of the two-month period, advanced imaging techniques and tissue analysis revealed that the rats on the omega-3 diet had maintained better hydration and displayed less damage to their intervertebral discs compared to the control group.
These findings suggest that incorporating eicosapentaenoic acid into the diet could reduce the inflammation linked to disc degeneration, potentially offering a protective effect against the progression of back pain. This research opens pathways to exploring omega-3s as a viable treatment option for people suffering from chronic back issues.
Read More
8
l-Serine and EPA reduce pain
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Study relevance: Moderate
We investigated whether l-serine and EPA could help relieve chronic low-back and knee pain in adults. In a well-structured study with 120 participants, half received a combination of these compounds while the other half received a placebo. After eight weeks, results showed that those taking l-serine and EPA experienced significant pain relief.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
Read More
8
Omega-3 benefits for back pain
Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.
Moderate relevance to back pain
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
No leg pain
These softgels are fantastic and do the job well. I used to suffer from pain in my legs, but since taking this fish oil, I no longer experience any pain. I can now bend down to clean the cat litter with ease. I wouldn't go back to the 1200mg fish oil as it caused my legs to hurt again.
Read More
8.8
Eliminated back pain
Triple Strength is remarkable. I often hear complaints about fish oil capsules tasting too fishy, but these are splendid. They seem to have alleviated my back muscle pain. Additionally, I take them for my high triglycerides.
8.8
Less pain
Bought at a significant discount and very pleased with the quality and quantity. I've been taking three tablets daily for four months, and I recommend them. They have noticeably improved my health and reduced my back pain.
Frequently Asked Questions
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