Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size: 1 Caplet
Amount Per Serving
%DV
Potassium (as Potassium Gluconate)
99 mg
2%

Top Medical Research Studies

8
Potassium may moderately affect migraines
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.

While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
Read More
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
We aimed to see if levcromakalim, a potassium channel opener, could trigger migraine-like headaches in individuals suffering from persistent post-traumatic headaches. In a robust, double-blind trial, participants received either levcromakalim or a placebo on different days and reported their headache experiences.

Surprisingly, over half of those receiving levcromakalim noted migraine-like headaches, marking a significant difference compared to those who received the placebo. This suggests that potassium channels are crucial in these headaches and may pave the way for new treatments using potassium channel blockers.
Read More

Most Useful Reviews

9
Helps with headaches
2 people found this helpful
Inexpensive and essential for summer when potassium intake is crucial. This supplement helped me avoid headaches during the heat and made me feel better. I definitely recommend it; it has assisted me more than once.
Read More
9
Relieves headaches
I really like this! I've been taking potassium for ages. In summer, when there's intense heat and potassium is lost rapidly, a headache can occur. This brand's potassium saved me; just two tablets and the headache vanished. I’ll also take it in winter as we eat less green, and potassium is needed. This company is reliable, with no complaints. Highly recommended!
Read More
7.5
Alleviates headaches
2 people found this helpful
I purchased this for its diuretic properties. Since I began drinking it as a temporary remedy, symptoms of weather sickness, like dizziness and headache, have improved. The value for money is also good and I recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
  • All Researches
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
We aimed to see if levcromakalim, a potassium channel opener, could trigger migraine-like headaches in individuals suffering from persistent post-traumatic headaches. In a robust, double-blind trial, participants received either levcromakalim or a placebo on different days and reported their headache experiences.

Surprisingly, over half of those receiving levcromakalim noted migraine-like headaches, marking a significant difference compared to those who received the placebo. This suggests that potassium channels are crucial in these headaches and may pave the way for new treatments using potassium channel blockers.
Read More
8
Potassium may moderately affect migraines
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.

While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
Read More
We explored how BK channels might relate to persistent post-traumatic headaches by examining the effects of MaxiPost, a BK channel opener. In a carefully designed study, participants with PPTH received either MaxiPost or a placebo during two sessions, separated by a week.

We found that MaxiPost could induce migraine-like headaches in individuals with PPTH, highlighting a potential target for new headache treatments through BK channel blockade. Further research is necessary to understand this connection and its therapeutic implications.
Read More
7
Potassium channel activation may induce headaches
We explored whether opening potassium channels could trigger cluster headache attacks. In a trial involving 41 participants divided into different headache categories, we administered levcromakalim, a potassium channel opener, or a placebo on separate days.

Our findings were intriguing; 60% of those with episodic cluster headaches experienced attacks after levcromakalim, compared to just 10% with the placebo. For chronic headache patients, 29% reported attacks post-levcromakalim, while those in remission showed no significant effects.

These results suggest that activating potassium channels can induce headaches in certain groups, highlighting a possible new avenue for treatment strategies.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Helps with headaches
2 people found this helpful
Inexpensive and essential for summer when potassium intake is crucial. This supplement helped me avoid headaches during the heat and made me feel better. I definitely recommend it; it has assisted me more than once.
Read More
9
Relieves headaches
I really like this! I've been taking potassium for ages. In summer, when there's intense heat and potassium is lost rapidly, a headache can occur. This brand's potassium saved me; just two tablets and the headache vanished. I’ll also take it in winter as we eat less green, and potassium is needed. This company is reliable, with no complaints. Highly recommended!
Read More
7.5
Alleviates headaches
2 people found this helpful
I purchased this for its diuretic properties. Since I began drinking it as a temporary remedy, symptoms of weather sickness, like dizziness and headache, have improved. The value for money is also good and I recommend it.
Read More
7.5
Prevents headaches
1 people found this helpful
I buy this for summer; I consume salt and potassium to combat weakness and prevent headaches during the heat.
Read More
7.5
Prevents morning headaches
16 people found this helpful
I take potassium at bedtime to avoid morning headaches. Two caplets of 99mg do the trick. This Nature's Bounty formula works effectively and is easy to swallow.
Read More

Frequently Asked Questions

9
Relieves headaches
I really like this! I've been taking potassium for ages. In summer, when there's intense heat and potassium is lost rapidly, a headache can occur. This brand's potassium saved me; just two tablets and the headache vanished. I’ll also take it in winter as we eat less green, and potassium is needed. This company is reliable, with no complaints. Highly recommended!
9
Helps with headaches
2 people found this helpful
Inexpensive and essential for summer when potassium intake is crucial. This supplement helped me avoid headaches during the heat and made me feel better. I definitely recommend it; it has assisted me more than once.
7.5
Prevents headaches
1 people found this helpful
I buy this for summer; I consume salt and potassium to combat weakness and prevent headaches during the heat.
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
7
Potassium channel activation may induce headaches
We explored whether opening potassium channels could trigger cluster headache attacks. In a trial involving 41 participants divided into different headache categories, we administered levcromakalim, a potassium channel opener, or a placebo on separate days.

Our findings were intriguing; 60% of those with episodic cluster headaches experienced attacks after levcromakalim, compared to just 10% with the placebo. For chronic headache patients, 29% reported attacks post-levcromakalim, while those in remission showed no significant effects.

These results suggest that activating potassium channels can induce headaches in certain groups, highlighting a possible new avenue for treatment strategies.
0
Potasium salt showed no headache relief
This large trial looked at whether swapping regular salt for a potassium-enriched version could help reduce headaches in people at risk for strokes or high blood pressure.

After monitoring nearly 21,000 participants over an average of 4.7 years, we found that those who used potassium salt did not experience fewer or less severe headaches compared to those who continued with regular salt.

In fact, headache reports were similar across both groups, indicating that potassium salt substitution might not be the solution for headache relief.
8
Potassium may moderately affect migraines
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.

While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.

References

  1. Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, et al. Hypersensitivity to BK channel opening in persistent post-traumatic headache. J Headache Pain. 2024;25:102. doi:10.1186/s10194-024-01808-0
  2. Kokoti L, Al-Karagholi MA, Zhuang ZA, Amirguliyev S, Amin FM, et al. Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial. Cephalalgia. 2024;44:3331024241248211. doi:10.1177/03331024241248211
  3. Haghdoost F, Gnanenthiran SR, Shan S, Kaistha P, Huang L, et al. The effect of salt substitution on frequency and severity of headache: results from the SSaSS cluster-randomised controlled trial of 20,995 participants. Eur J Clin Nutr. 2024;78:401. doi:10.1038/s41430-024-01419-7
  4. Raffaelli B, Do TP, Chaudhry BA, Amin FM, Ashina H, et al. Activation of ATP-sensitive potassium channels triggers migraine attacks independent of calcitonin gene-related peptide receptors: a randomized placebo-controlled trial. Cephalalgia. 2024;44:3331024231222916. doi:10.1177/03331024231222916
  5. Al-Khazali HM, Deligianni CI, Pellesi L, Al-Karagholi MA, Ashina H, et al. Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial. Pain. 2024;165:1289. doi:10.1097/j.pain.0000000000003130
  6. Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Burstein R, et al. Hypersensitivity to opening of ATP-sensitive potassium channels in post-traumatic headache. Cephalalgia. 2023;43:3331024231210930. doi:10.1177/03331024231210930
  7. Xu L, Zhang C, Liu Y, Shang X, Huang D. Association between dietary potassium intake and severe headache or migraine in US adults: a population-based analysis. Front Nutr. 2023;10:1255468. doi:10.3389/fnut.2023.1255468
image