We encountered a case of a woman suffering from short bowel syndrome, who faced significant hair loss due to biotin deficiency while on home parenteral nutrition. After starting oral biotin supplementation of 10 mg/day for three weeks, we observed that her serum biotin levels increased, leading to noticeable new hair growth and resolution of other symptoms. Further intravenous biotin treatment maintained her on multivitamins that include biotin, preventing any future deficiency symptoms. This case highlights the importance of addressing biotin levels for hair health and overall well-being.
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9.5
Biotin therapy improves hair growth
Biotinidase deficiency characterized by skin and hair findings.
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
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8
Vitamin E improves rabbit skin health
Topical effect of a specific spot-on treatment made of natural ingredients in rabbits () with skin problems: A pilot study.
We assessed the impact of a topical solution featuring essential oils, polyunsaturated fatty acids, and Vitamin E on rabbits facing skin diseases. The study included thirty New Zealand rabbits divided into two groups: one treated with the natural formula and a control group.
Over the treatment period, we observed notable improvements in hair shine, hydration, and a reduction in flaking, bad odor, and hair loss in the treatment group. In contrast, the control group showed no such benefits. Overall, this suggests that Vitamin E combined with other natural ingredients can enhance skin and hair health in rabbits.
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Most Useful Reviews
9
Reduces hair loss
8 people found this helpful
The manufacturer suggests taking two pieces daily, but I prefer one at a time as each contains 2500 mcg of biotin, which is within the daily recommendation of 2000-3000. I use them in a course, finishing a jar once a year, usually in spring. I have noticeably reduced hair loss, strengthened my nails, and improved my skin.
Read More
9
Fast hair growth
7 people found this helpful
Really great and fast results! The delicious gummies have a wonderful texture! My hair has become significantly stronger, and I’ve noticed much less hair loss. My hair also grew faster. I highly recommend this product!
Read More
9
Boosts hair growth
5 people found this helpful
Excellent! I adore these vitamins in jelly candy form for hair, skin, and nails, with a delightful strawberry flavour. Biotin and vitamin B7 support hair growth and are vital for the skin while also aiding in halting hair loss. I highly recommend them!
The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study.
We investigated the effectiveness of the Dr. SKS Hair Booster Serum, which contains biotin and other micronutrients, for treating androgenetic alopecia in both men and women. This open-label study included 1,000 participants across multiple clinics in India who received the serum through mesotherapy or derma roller techniques for six months.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
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9.5
Alopecia areata improvement with tofacitinib
Resistant Alopecia Areata Treated with Tofacitinib.
We explored the effectiveness of tofacitinib, a treatment showing promise for alopecia areata (AA), particularly in cases that have proven resistant to other therapies. In one instance, a young adult male with resistant AA had not responded to treatments like oral and topical steroids, minoxidil, and oral troxasalen.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
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9.5
Biotin therapy improves hair growth
Biotinidase deficiency characterized by skin and hair findings.
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
9
Dr. SKS Hair Booster efficacy
Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study.
We explored the effectiveness of Dr. SKS Hair Booster Serum, which contains biotin among other ingredients, in treating female pattern hair loss (FPHL) in women diagnosed with polycystic ovary syndrome (PCOS). Our study included 1,000 females aged 25-50 who experienced hair loss classified as Ludwig grades I and II.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
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9
Biotin improves diffuse hair loss
Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands.
We conducted a study to evaluate how effective biotin, when combined with dexpanthenol injections, is at treating diffuse hair loss. In our research, fifty participants suffering from this condition were divided into two groups to receive six weekly injections of different brands of the treatment—one from Pars Behvarzan and the other from Bayer.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
The manufacturer suggests taking two pieces daily, but I prefer one at a time as each contains 2500 mcg of biotin, which is within the daily recommendation of 2000-3000. I use them in a course, finishing a jar once a year, usually in spring. I have noticeably reduced hair loss, strengthened my nails, and improved my skin.
Read More
9
Fast hair growth
7 people found this helpful
Really great and fast results! The delicious gummies have a wonderful texture! My hair has become significantly stronger, and I’ve noticed much less hair loss. My hair also grew faster. I highly recommend this product!
Read More
9
Boosts hair growth
5 people found this helpful
Excellent! I adore these vitamins in jelly candy form for hair, skin, and nails, with a delightful strawberry flavour. Biotin and vitamin B7 support hair growth and are vital for the skin while also aiding in halting hair loss. I highly recommend them!
Read More
7.5
Significant improvement
4 people found this helpful
I really like the effect it gives me; I see a substantial improvement in my hair loss. I began with small boxes, but moved on to larger ones because I am meticulous and truly see the difference. I ensure to take two every day.
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9
Effective for hair
3 people found this helpful
I really liked the vitamins! After dealing with hair loss post-coronavirus, I decided to try these vitamins. To my surprise, the outcome has been remarkable. They taste sweet, making it easy to remember to take them. My hair has significantly reduced falling, and my nails are now stronger with no breakage. They caused no rashes, which was a past issue with other supplements. I'm extremely pleased and will repurchase.
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
Hair Skin Nails Formulas are dietary supplements designed to support the health of hair, skin, and nails. These formulations typically contain a blend of vitamins, minerals, and other nutrients that are believed to promote the growth and strength of hair and nails while also enhancing skin health. Common ingredients include biotin, collagen, vitamins A, C, and E, as well as minerals like zinc and silica, which are all known for their beneficial effects on beauty and wellness.
Consumers often seek out Hair Skin Nails Formulas to address specific concerns such as thinning hair, brittle nails, and skin aging. While many users report positive results, it's important to keep in mind that individual responses can vary, and factors like diet, genetics, and overall health play a significant role in the condition of your hair, skin, and nails. Always consult with a healthcare provider before starting any new supplement regimen, especially if you have underlying health conditions or are taking other medications.
Hair Skin Nails formulas are supplements designed to support the health of hair, skin, and nails by providing essential vitamins and minerals. Common ingredients include biotin, vitamin C, vitamin E, and various B vitamins, which are known to play a role in maintaining healthy hair and possibly preventing hair loss. While many users report improvements in hair thickness and shine after incorporating these supplements into their routine, it's important to note that results can vary significantly from person to person.
However, Hair Skin Nails formulas should not be seen as a catch-all solution for hair loss. Factors contributing to hair loss can be complex, involving genetics, hormonal changes, and overall health. Therefore, while these supplements may promote healthier hair growth in some cases, they are unlikely to address the root causes of hair loss. If you're experiencing significant hair loss, it's advisable to consult with a healthcare professional to explore the underlying issues and get personalized recommendations. In summary, Hair Skin Nails formulas may provide support for hair health, but they should not replace a thorough medical evaluation for persistent hair loss concerns.
Based on user reviews, most individuals report noticeable improvements in hair loss after about 2 to 3 weeks of consistent use of the supplement. For instance, one user noted that their hair loss was almost entirely halted within three weeks, with only a few strands compared to dozens beforehand Read Review. Another user mentioned that they experienced a significant decrease in hair fall within just one week Read Review. Additionally, a review indicated that after taking the vitamins for a fortnight, they saw marked improvement not only in hair loss but also in skin and nail strength Read Review.
Overall, while results may vary, users tend to agree that a commitment of a few weeks is necessary to witness positive changes. Many reviews emphasize the importance of remaining consistent with the supplement for optimal effects, as evidenced by accounts of improved hair and decreased shedding after adhering to a regimen over several weeks Read Review.
While there are studies supporting the connection between certain supplements and hair loss treatments, the evidence for biotin—often touted as a hair growth aid—is mixed at best. For instance, a thorough review of various studies suggests that while biotin supplementation may benefit those with a deficiency, it does not significantly promote hair growth in individuals with normal biotin levels [4]. Additionally, trials evaluating biotin's effectiveness alongside other treatments, such as isotretinoin or in combination with various therapies, indicate improvement in hair health; however, isolating biotin's specific effects remains challenging [12].
On the other hand, other research highlights positive effects from ingredients like tocotrienol—another member of the vitamin E family—demonstrating a 34.5% increase in hair count among participants [3]. Additionally, studies featuring topical solutions that included biotin alongside essential oils and vitamins showed promising results for hair health improvements in experimental settings [1]. Overall, while biotin might contribute positively in certain contexts, more research is warranted to clarify its role and effectiveness in treating hair loss independently.
Based on user reviews, many individuals report substantial improvements in their hair health after using the supplement. Notably, several users have highlighted the near-complete cessation of hair loss within just a few weeks of consistent use. For example, one user experienced a dramatic decrease in hair fall after three weeks, where they only noticed a few strands compared to dozens before Read Review. Another user mentioned that their hair loss was fully stopped within a week of starting the vitamins, showcasing the potential speed of the results Read Review.
Additionally, users have not only reported improvements in hair loss but also noted strengthened nails and enhanced skin quality. For instance, one user mentioned that they saw a marked improvement in their nails alongside reduced hair shedding after a couple of weeks of supplementation Read Review. While individual results can vary, the overall consensus is that regular use of these vitamins can yield significant benefits for hair, skin, and nail health, leading to enhanced overall satisfaction among users Read Review.
Based on user reviews, many individuals report that combining this supplement with other health regimens can enhance the effects on hair loss. Some users have found that taking the vitamins consistently alongside a balanced diet significantly boosts their effectiveness. For instance, one reviewer mentioned they take the vitamins seasonally, which aligns with their personal health strategy, helping to diminish excessive hair loss within just a week of starting the regimen Read Review. Another user emphasized the importance of a consistent intake throughout the year, observing remarkable outcomes with regular use, leading to a substantial reduction in hair loss over time Read Review.
Some reviewers also suggest that the vitamins not only help with hair but also improve the overall health of skin and nails, hinting that a holistic approach might yield better results Read Review. Additionally, the appealing taste and forms of the vitamins, such as gummies, make it easier for individuals to remember taking them consistently, which is crucial for optimal efficacy. This aspect reinforces the idea that a combination of consistent use and possibly an integrated approach to overall wellness can lead to more favorable outcomes in managing hair loss Read Review.
Based on user reviews, the right dosage for Hair Skin Nails Formulas appears to vary, with a common recommendation being two gummies daily. Many users, like the reviewer with ID '8717f017-b1d6-4963-bc39-b31784571f41', suggest that this dosage aligns well with the daily biotin recommendations, which range from 2000 to 3000 mcg. Some users, such as the one with ID '7a722d4c-5429-4dd5-bf4d-baff7e8d3b36', report significant hair loss reduction after consistently taking two gummies per day, while others find success with lower doses, like one gummy a day, crediting this for improvements in hair strength and overall health.Read ReviewRead Review
Moreover, several reviewers underscore the importance of following a consistent regimen, often cycling their use through different seasons or after certain life events. For instance, one user (review ID '64b19729-97bf-43a2-9468-7330f34b70af') noted marked improvements in hair loss reduction within weeks of taking them, while another (review ID 'c1aa7589-86fd-43fb-a8de-512ba861bd83') reported a drastic reduction in hair loss after committing to a spring and autumn routine. Overall, while many users report positive results with a daily intake of two gummies, individual experiences may vary, suggesting potential flexibility in dosage based on personal preference and response to the product.Read ReviewRead Review
9
Stops shedding
2 people found this helpful
Remarkable results! Initially sceptical that gummies could halt hair loss, I was pleasantly surprised. After three weeks, my hair almost stopped falling out—only a few strands compared to dozens beforehand! Highly recommend!
9
Improved hair loss
1 people found this helpful
I’ve been experiencing hair loss, and after reading many recommendations online, I began taking 2-4 capsules daily for about a fortnight. My hair loss has improved significantly, my skin and nails are stronger, and the strawberry flavour is delicious!
9
Reduction in hair loss
3 people found this helpful
It works! These are the only vitamins that have worked for my hair. I’ve ordered them multiple times and try to follow a course in spring and autumn. Previously, I would lose a lot of hair when washing, but after starting treatment, the hair loss reduced by more than 80%.
9
Eliminated hair loss
2 people found this helpful
Yummy for hair! After using this, my hair began to fall out excessively; in 2 months, I lost half of my braid. However, within a week, these vitamins completely stopped my hair loss! A nice bonus is the pleasant taste and lovely pink packaging. The jar has a lid to keep it safe from children, and I take it twice a day with meals.
9
Effective for hair
3 people found this helpful
I really liked the vitamins! After dealing with hair loss post-coronavirus, I decided to try these vitamins. To my surprise, the outcome has been remarkable. They taste sweet, making it easy to remember to take them. My hair has significantly reduced falling, and my nails are now stronger with no breakage. They caused no rashes, which was a past issue with other supplements. I'm extremely pleased and will repurchase.
9
Significant reduction
1 people found this helpful
I take these vitamins seasonally, in autumn and spring, and they really help me. I have an issue with excessive hair loss, which diminishes after a week of taking these vitamins. Within 2-3 weeks, my hair practically stops falling out. I’m pleased.
9
Reduces hair loss
8 people found this helpful
The manufacturer suggests taking two pieces daily, but I prefer one at a time as each contains 2500 mcg of biotin, which is within the daily recommendation of 2000-3000. I use them in a course, finishing a jar once a year, usually in spring. I have noticeably reduced hair loss, strengthened my nails, and improved my skin.
7.5
Significant improvement
4 people found this helpful
I really like the effect it gives me; I see a substantial improvement in my hair loss. I began with small boxes, but moved on to larger ones because I am meticulous and truly see the difference. I ensure to take two every day.
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
8
Biotin positively impacts hair loss
Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss.
We examined the relationship between the microbiome and hair loss, particularly focusing on a newly identified strain called Cicaria. In our observation, we set up two groups: one experiencing hair loss and another with healthy scalps for comparison. We noted significant differences in the microbial compositions of the two groups, which got us curious about how these could be linked to hair health.
From Cicaria, we successfully isolated two key components—adenosine and biotin. Through further testing with human hair follicles, we discovered that the group treated with adenosine showed increased hair follicle length and maintained diameter, which are promising signs of healthy hair growth.
What’s more, the treatments involving both Cicaria culture medium and biotin kept hair follicles in the anagen (growth) phase for a longer time. This delay in transitioning to the catagen phase suggests a strong potential for biotin in aiding hair retention. Overall, it seems that biotin, particularly when sourced from the microbiome, has a positive effect on preventing hair loss and promoting healthier hair growth.
8
Tocotrienol increases hair count
Effects of tocotrienol supplementation on hair growth in human volunteers.
In a study examining the effects of tocotrienol, a potent antioxidant in the vitamin E family, we found encouraging results for hair growth. Volunteers dealing with hair loss were split into two groups: one received tocotrienol supplements, while the other took a placebo.
Over eight months, those taking tocotrienols experienced a remarkable 34.5% increase in hair count compared to a slight decline in the placebo group.
However, the overall hair weight did not show significant changes. This suggests that tocotrienols may promote hair growth by alleviating oxidative stress linked to hair loss.
8
Vitamin E improves rabbit skin health
Topical effect of a specific spot-on treatment made of natural ingredients in rabbits () with skin problems: A pilot study.
We assessed the impact of a topical solution featuring essential oils, polyunsaturated fatty acids, and Vitamin E on rabbits facing skin diseases. The study included thirty New Zealand rabbits divided into two groups: one treated with the natural formula and a control group.
Over the treatment period, we observed notable improvements in hair shine, hydration, and a reduction in flaking, bad odor, and hair loss in the treatment group. In contrast, the control group showed no such benefits. Overall, this suggests that Vitamin E combined with other natural ingredients can enhance skin and hair health in rabbits.
References
Waisburd GS, Cordero AM, Núñez CR, Contreras LM, Cárdenas RH, et al. Topical effect of a specific spot-on treatment made of natural ingredients in rabbits () with skin problems: A pilot study. Vet World. 2020;13:1760. doi:10.14202/vetworld.2020.1760-1763
Zhou Y, Tang G, Li X, Sun W, Liang Y, et al. Study on the chemical constituents of nut oil from Prunus mira Koehne and the mechanism of promoting hair growth. J Ethnopharmacol. 2020;258:112831. doi:10.1016/j.jep.2020.112831
Beoy LA, Woei WJ, Hay YK. Effects of tocotrienol supplementation on hair growth in human volunteers. Trop Life Sci Res. 2010;21:91.
Yelich A, Jenkins H, Holt S, Miller R. Biotin for Hair Loss: Teasing Out the Evidence. J Clin Aesthet Dermatol. 2024;17:56.
Qiu S, Pan Z, Jiang X, Lv G, Feng A, et al. The synergistic effect of phototherapy and active substances on hair growth. J Photochem Photobiol B. 2024;259:113008. doi:10.1016/j.jphotobiol.2024.113008
Valentim FO, Miola AC, Miot HA, Schmitt JV. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. An Bras Dermatol. 2024;99:581. doi:10.1016/j.abd.2023.07.008
Khare S. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e44941. doi:10.7759/cureus.44941
Tr P, Ts R, K SK, Prasanna H. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia. Cureus. 2023;15:e38696. doi:10.7759/cureus.38696
Khare S. The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e37424. doi:10.7759/cureus.37424
Sahay G. Resistant Alopecia Areata Treated with Tofacitinib. Int J Trichology. 2022;14:181. doi:10.4103/ijt.ijt_63_22
Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136
Samadi A, Ketabi Y, Firooz R, Firooz A. Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther. 2022;35:e15695. doi:10.1111/dth.15695
Starace M, Gurioli C, Carpanese MA, Bruni F, Piraccini BM, et al. Short anagen syndrome: A case series and algorithm for diagnosis. Pediatr Dermatol. 2021;38:1157. doi:10.1111/pde.14750
Aksac SE, Bilgili SG, Yavuz GO, Yavuz IH, Aksac M, et al. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. Int J Dermatol. 2021;60:980. doi:10.1111/ijd.15485
Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
Şen O, Türkçapar AG. Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements. J Laparoendosc Adv Surg Tech A. 2021;31:296. doi:10.1089/lap.2020.0468
Marotta JC, Patel G, Carvalho M, Blakeney S. Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution. Int J Pharm Compd. 2020;24:69.
Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4
Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Cell Rep. 2017;20:1513. doi:10.1016/j.celrep.2017.07.057
Castro-Gago M, Pérez-Gay L, Gómez-Lado C, Castiñeiras-Ramos DE, Otero-Martínez S, et al. The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity. J Child Neurol. 2011;26:1522. doi:10.1177/0883073811409227
Castro-Gago M, Gómez-Lado C, Eirís-Puñal J, Díaz-Mayo I, Castiñeiras-Ramos DE. Serum biotinidase activity in children treated with valproic acid and carbamazepine. J Child Neurol. 2010;25:32. doi:10.1177/0883073809336118
Schulpis KH, Karikas GA, Tjamouranis J, Regoutas S, Tsakiris S. Low serum biotinidase activity in children with valproic acid monotherapy. Epilepsia. 2001;42:1359.
Khalidi N, Wesley JR, Thoene JG, Whitehouse WM, Baker WL. Biotin deficiency in a patient with short bowel syndrome during home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1984;8:311.