Supplement Facts
Serving Size: 1 Caplet
Amount Per Serving
%DV
Zinc (as Zinc Gluconate)
50 mg
455%
The product is found useful for the following medical conditions
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 115 Reviews
8.8
8
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
9.5
Prevention of colds
Most Useful Review
I take it with vitamin C as recommended by my doctor during an epidemic for prevention and at the first sign of a cold. It helps from the first day of taking the capsules. I always keep this medication in my home medicine cabinet and highly recommend it to everyone!
Flu details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 23 Reviews
8.7
8
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9.5
Quick recovery aid
Most Useful Review
Zinc is essential for influenza and acute respiratory viral infections, aiding in quicker recovery.
Hair Loss details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Good
Based on 40 Reviews
8.7
9
We explored how zinc acetate hydrate impacts hair loss for patients experiencing symptoms after COVID-19. In our analysis, we looked at 120 symptomatic outpatients over 12 weeks, observing their recovery patterns and any improvements in their symptoms. The focus was on various lingering effects, including fatigue and hair loss, particularly how zinc could potentially alleviate these issues.
Our findings highlighted significant improvements in hair loss for those treated with zinc acetate hydrate at multiple checkpoints (4, 8, and 12 weeks) compared to those who did not receive this treatment. The results were statistically significant and suggested that zinc could be a useful option for those struggling with hair loss post-COVID-19.
Additionally, we noted improvements in fatigue among those receiving zinc, although this was not as pronounced at all time intervals. As a whole, our study emphasized zinc's beneficial effects, particularly for hair loss, providing promising insights for anyone dealing with these challenging post-viral symptoms.
Our findings highlighted significant improvements in hair loss for those treated with zinc acetate hydrate at multiple checkpoints (4, 8, and 12 weeks) compared to those who did not receive this treatment. The results were statistically significant and suggested that zinc could be a useful option for those struggling with hair loss post-COVID-19.
Additionally, we noted improvements in fatigue among those receiving zinc, although this was not as pronounced at all time intervals. As a whole, our study emphasized zinc's beneficial effects, particularly for hair loss, providing promising insights for anyone dealing with these challenging post-viral symptoms.
9.5
Enhanced vitamin absorption
Most Useful Review
Great for hair loss; it aids in diminishing hair loss and increases the absorption of essential vitamins, particularly biotin. I appreciate it and hope for continued benefits.
Whooping Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Effective treatment
Most Useful Review
Excellent! I don’t take it on a regular basis, but I remember using it during cold season when a cough disrupts daily life. I double (or even triple) the dose, and within two days, everything is fine. It works, and I just need to encourage my family and myself to take it daily.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 18 Reviews
8.6
8
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
9.5
Effective treatment
Most Useful Review
I have been struggling with breakouts caused by hormones. This supplement has been a miracle for me, significantly reducing my pimples and eliminating cystic acne!
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
We investigated how intranasal zinc (Zn) treatment affects symptoms of allergic rhinitis (AR), specifically focusing on individuals suffering from Japanese cedar pollinosis (JCP), a common seasonal allergy. In our study, we monitored 57 control subjects and 44 patients from preseason through the allergy season, observing the levels of Zn in both nasal fluid and serum.
Our findings showed that after exposure to pollen, the level of zinc in the nasal lining fluid of JCP patients significantly increased, while their serum zinc levels notably decreased compared to the control group during the JCP season. To delve deeper, we used model mice that could mimic these changes and the allergy symptoms of the patients.
The results from this mouse study were promising. We observed that treating these mice with a dose of zinc, similar to what humans might use, led to a notable improvement in their allergy symptoms. Additionally, the number of mucin-secreting goblet cells, which indicate a response to allergies, significantly decreased following the zinc treatment.
Our study points towards the potential of using intranasal zinc as a way to alleviate allergy symptoms, suggesting a new approach to managing allergic rhinitis.
Our findings showed that after exposure to pollen, the level of zinc in the nasal lining fluid of JCP patients significantly increased, while their serum zinc levels notably decreased compared to the control group during the JCP season. To delve deeper, we used model mice that could mimic these changes and the allergy symptoms of the patients.
The results from this mouse study were promising. We observed that treating these mice with a dose of zinc, similar to what humans might use, led to a notable improvement in their allergy symptoms. Additionally, the number of mucin-secreting goblet cells, which indicate a response to allergies, significantly decreased following the zinc treatment.
Our study points towards the potential of using intranasal zinc as a way to alleviate allergy symptoms, suggesting a new approach to managing allergic rhinitis.
10
Effective allergy relief
Most Useful Review
Helped to alleviate my seasonal allergies! I wanted to share my honest thoughts on this Zinc supplement. About ten days ago, I began experiencing seasonal allergies, with itchy eyes and a constantly runny nose. I started taking Zinc, Vitamin D3 5000 IU, and ascorbate. Now, on the tenth day, my allergies have vanished! It seems this vitamin truly works, boosting my immunity and eliminating the allergy symptoms. I haven't taken any other medications apart from these vitamins. I also recommend it for colds. I give my children half a tablet every day. If you found my review helpful, please support it with likes. Thank you in advance!
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
We explored how zinc affects blood clotting, particularly through a substance called Zn@SiO nanocomposite. This material shows promise as a hemostatic agent, which means it helps stop bleeding by promoting the formation of stable blood clots.
During our analysis, we examined various aspects of how this nanocomposite interacts with blood. It activates specific factors in the coagulation cascade—the process our bodies use to form clots. With the presence of zinc in the material, we observed enhanced activation of these factors, leading to improved clot formation.
Our research involved synthesizing and characterizing the Zn@SiO nanocomposite using several methods, including XRD, FTIR, and HRTEM. We also tested its effects on red blood cell aggregation, platelet adhesion, and several vital clotting time measures. The results indicate that Zn@SiO has significant hemostatic properties, showing potential for use in surgeries and trauma care.
This study highlights the exciting role of zinc in optimizing hemostasis, making it a candidate worth considering for medical applications related to bleeding management.
During our analysis, we examined various aspects of how this nanocomposite interacts with blood. It activates specific factors in the coagulation cascade—the process our bodies use to form clots. With the presence of zinc in the material, we observed enhanced activation of these factors, leading to improved clot formation.
Our research involved synthesizing and characterizing the Zn@SiO nanocomposite using several methods, including XRD, FTIR, and HRTEM. We also tested its effects on red blood cell aggregation, platelet adhesion, and several vital clotting time measures. The results indicate that Zn@SiO has significant hemostatic properties, showing potential for use in surgeries and trauma care.
This study highlights the exciting role of zinc in optimizing hemostasis, making it a candidate worth considering for medical applications related to bleeding management.
9.5
Normalised levels
Most Useful Review
Wow, my hair and nails adore this! I was depleted three months ago when I had blood work done. When I repeated the blood work a few days ago, I was thrilled to see my levels within the normal range, which I had already noticed by the improvement in my hair and nails.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Improved sharpness
Most Useful Review
I don’t have a specific health issue prompting me to take zinc, but after taking my first caplet, I quickly noticed that my eye vision became sharper and my mind was less foggy. I've learned that zinc can enhance the immune system in various ways, one of which could help with tinnitus if there’s a zinc deficiency. Additionally, I’ve noticed that my hair and nails have strengthened, and I intend to continue taking it. To maximise absorption, zinc should be taken on an empty stomach or between meals and away from other supplements.
Brain Tumor details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
We evaluated the potential of zinc in combination with a ketogenic diet and oxyresveratrol in fighting glioblastoma, a highly aggressive brain tumor. Through a series of carefully designed experiments, we examined how these treatments affect tumor growth and overall brain function.
In our study, we induced brain tumors in Wistar rats and then applied our treatment regimen. We tracked various outcomes, including tumor size, proliferation rates, memory function, and motor coordination. By assessing glucose and ketone levels, we gained insights into the metabolic changes occurring as a result of the treatments.
The findings suggested that zinc played a supportive role alongside the ketogenic diet and oxyresveratrol in reducing tumor growth. Moreover, these treatments appeared to enhance memory and motor coordination, indicating a multi-faceted benefit. Overall, this progression offered valuable information about the role of diet and supplementary compounds in battling aggressive brain tumors like glioblastoma.
In our study, we induced brain tumors in Wistar rats and then applied our treatment regimen. We tracked various outcomes, including tumor size, proliferation rates, memory function, and motor coordination. By assessing glucose and ketone levels, we gained insights into the metabolic changes occurring as a result of the treatments.
The findings suggested that zinc played a supportive role alongside the ketogenic diet and oxyresveratrol in reducing tumor growth. Moreover, these treatments appeared to enhance memory and motor coordination, indicating a multi-faceted benefit. Overall, this progression offered valuable information about the role of diet and supplementary compounds in battling aggressive brain tumors like glioblastoma.
9
Improved brain function
Most Useful Review
This dietary supplement contains zinc gluconate, which has a 60% digestibility rate, making it preferable since zinc can be difficult to absorb. For instance, zinc oxide might not be absorbed at all. Therefore, when purchasing dietary supplements with zinc, it's essential to check the type of zinc used; otherwise, you may end up with ineffective products. Since taking zinc, I've noticed a slight reduction in the fat content of my facial skin and scalp. I feel more cheerful overall, and it seems that my brain activity, memory, and concentration have improved significantly.
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Prevents chronic cough
Most Useful Review
After my young son coughed on me, I felt a cold approaching the next day. I took zinc and echinacea and fortunately avoided it. I’ve learnt it should be taken with food as it upset my stomach otherwise. I’ve been taking this over the past year, halving my daily intake for my immune system, and it helps fight colds and shortens their duration.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.6
7
We explored the relationship between serum zinc levels and chronic fatigue syndrome (CFS) in a study that compared patients with CFS to normal volunteers. By using an atomic absorption method, we measured serum zinc concentrations and found that those suffering from CFS had significantly lower levels of zinc compared to healthy individuals.
Interestingly, we observed a trend indicating that lower zinc levels correlated with greater CFS severity. Patients also reported a negative correlation between their zinc levels and their subjective experiences of infection. This suggests that zinc plays a role in the immune dysfunction commonly seen in CFS.
Furthermore, we noted that lower serum zinc was associated with higher levels of inflammatory markers and certain defects in the early activation of T cells. Since zinc acts as a potent antioxidant, our findings indicate that CFS is linked to increased oxidative stress in these patients. Given this, it may be beneficial for some CFS patients to consider zinc supplements as part of their treatment approach.
Interestingly, we observed a trend indicating that lower zinc levels correlated with greater CFS severity. Patients also reported a negative correlation between their zinc levels and their subjective experiences of infection. This suggests that zinc plays a role in the immune dysfunction commonly seen in CFS.
Furthermore, we noted that lower serum zinc was associated with higher levels of inflammatory markers and certain defects in the early activation of T cells. Since zinc acts as a potent antioxidant, our findings indicate that CFS is linked to increased oxidative stress in these patients. Given this, it may be beneficial for some CFS patients to consider zinc supplements as part of their treatment approach.
9.5
Immunity boost
Most Useful Review
This zinc supplement has significantly helped me enhance my immunity, particularly during my recovery from COVID. I experienced weakness, fatigue, and cold sweat, all of which gradually subsided. I recommend zinc for supporting the entire immune system.
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 36 Reviews
8.6
9
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
8.3
Cold prevention essential
Most Useful Review
Excellent zinc! A must-have at the onset of a common cold or virus.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 4 Reviews
8.6
7
We aimed to uncover the connection between dietary zinc deficiency and symptoms associated with major depressive disorder (MDD). In our study, we used rats fed either a zinc-adequate diet or one deficient in zinc for four weeks.
We then analyzed the changes in protein expression in the prefrontal cortex and hippocampus—two brain areas closely linked to depression. This approach allowed us to see how zinc deficiency impacts the brain at a molecular level.
Our findings revealed that significant alterations occurred in proteins related to zinc transport and mitochondrial function due to the deficiency. In particular, we saw a notable decline in the activity of complex I of the mitochondrial energy production pathway in the prefrontal cortex.
These results suggest that low zinc levels can disrupt vital brain functions, potentially contributing to the development of depressive symptoms. This highlights the importance of maintaining adequate zinc levels for mental health.
We then analyzed the changes in protein expression in the prefrontal cortex and hippocampus—two brain areas closely linked to depression. This approach allowed us to see how zinc deficiency impacts the brain at a molecular level.
Our findings revealed that significant alterations occurred in proteins related to zinc transport and mitochondrial function due to the deficiency. In particular, we saw a notable decline in the activity of complex I of the mitochondrial energy production pathway in the prefrontal cortex.
These results suggest that low zinc levels can disrupt vital brain functions, potentially contributing to the development of depressive symptoms. This highlights the importance of maintaining adequate zinc levels for mental health.
9.5
Reduces depression effectively
Most Useful Review
Definitely a necessary addition! I've used this supplement for a long time, three times a year for 30 days with great results. It boosts mood and memory, alleviates depression and anxiety, reduces the formation of fatty plaques, strengthens the immune system, and regulates glucose metabolism. It's an antioxidant that protects cells and aids growth and development during puberty. For men, it governs testosterone formation, improves sperm motility, and supports prostate health, while in women, it is vital for ovulation, menstrual regularity, and breastfeeding.
Leg Cramps details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Stronger hair, immune boost
Most Useful Review
I take Zinc with other vitamins, which effectively stimulates my immune system. I’ve noticed my legs and hair have become stronger.
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Reduces infectious diseases
Most Useful Review
Zinc is an essential nutrient that must be obtained from food or supplements, as the body cannot produce it. A lack of zinc weakens immunity and makes one more prone to diseases, including pneumonia. Adequate zinc intake can strengthen immune response and improve healing processes.
Prostate Cancer details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.6
8
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
8.8
Enhances testosterone production
Most Useful Review
Zinc is essential for male health, particularly for testosterone production. A deficiency disrupts prostate function, reduces sex hormone levels, and deteriorates sperm quality. I appreciate Nature's Bounty for its price and quality. I take one tablet daily, which is suitable for vegetarians.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.6
8.8
Fewer rashes noted
Most Useful Review
I take zinc on my dermatologist's recommendation. There are significantly fewer rashes, and my hair has started to fall out less noticeably. I follow a regimen of three months on, one month off, repeating this cycle. So far, the results are evident. These vitamins have greatly benefitted me. If you find this review helpful, please respond with "Yes." Thank you!
Sleep Apnea details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
9.5
Insomnia relief
Most Useful Review
The first thing I noticed was that my insomnia disappeared. Previously, I struggled to fall asleep until two or three in the morning, despite wanting to sleep from nine. After a few days of zinc intake, I began falling asleep quickly and enjoyed uninterrupted, restful sleep all night.
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
We delved into an interesting case of a 76-year-old man who developed severe esophageal ulcers, likely due to zinc deficiency following a total gastrectomy. His symptoms included sore throat, heartburn, and difficulty swallowing.
After the diagnosis of zinc deficiency, he began oral zinc treatment. Remarkably, this led to significant symptom relief and visible healing of the ulcers during follow-up imaging. Impressively, he has maintained his zinc supplementation for five years without any recurrence of symptoms. This unique case shines a light on the potential role of zinc in ulcer healing.
After the diagnosis of zinc deficiency, he began oral zinc treatment. Remarkably, this led to significant symptom relief and visible healing of the ulcers during follow-up imaging. Impressively, he has maintained his zinc supplementation for five years without any recurrence of symptoms. This unique case shines a light on the potential role of zinc in ulcer healing.
9.5
Safe for ulcers
Most Useful Review
Very suitable for my family... safe for stomach ulcers and GERD.
Bloating details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
8.8
No bloating effects
Most Useful Review
These are high-quality supplements that I've been using for two weeks before and after Botox. They greatly enhance the longevity of results. One bottle provides enough for multiple courses. Just ensure to avoid taking them right after coffee to prevent any side effects such as bloating, abdominal pain, or nausea. I highly recommend these!
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
We conducted a randomized, double-blind, placebo-controlled trial to explore how zinc gluconate affects migraine symptoms in women. Sixty participants, with an average age of 35, were given either 15 mg of zinc per day or a placebo for 12 weeks, allowing us to measure the impact on headache frequency, duration, and intensity.
The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.
Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.
In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.
Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.
In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
8.8
No more headaches
Most Useful Review
This zinc is excellent. My test results after taking these pills were exceptional. However, 50 mg caused me severe headaches, which were unbearable. I contacted my doctor, who advised me to break the tablet in half and take half a tablet daily. Thankfully, I didn't experience any further headaches. The tablets are easy to swallow, and you can also break them in half effortlessly.
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
8
Strengthened immune system
Most Useful Review
Zinc plays a crucial role in bolstering my immune system. During viral outbreaks, a daily dose of 50 mg is precisely what I need to combat illness. Additionally, zinc is vital for prostate health. It’s important to complete the course. I combine zinc with 500 mg of vitamin C, 2000 IU of vitamin D-3, and 1000 mg of Omega-3. Take care of your health!
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9.5
No more pain
Most Useful Review
I purchased this for a family member suffering from stomach pains when hungry. Since I began taking it, I haven’t experienced any stomach pain when I’m hungry, so I will continue. At present, I opt for a slightly more affordable brand from iHerb, but this manufacturer is also commendable.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
6.3
Less bone pain
Most Useful Review
I purchased zinc, magnesium, calcium, and vitamin D in a concentrated form and took one of each type before bed. Thankfully, my bone pain has diminished, and the cracking in my bones has decreased.
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9.5
Effective for colds
Most Useful Review
Most beloved zinc! I’ve consistently ordered this for years and can feel its effect, particularly when I have a cold. Recovery is noticeably quicker, and relief is almost immediate.
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
We aimed to explore how zinc oxide nanoparticles (ZnO NPs) could protect the heart from damage caused by doxorubicin, a drug that can lead to serious heart issues, including myocardial infarction (MI). Our study involved rats that were injected with doxorubicin to induce MI and then treated with ZnO NPs at two different doses.
Throughout the research, we observed significant improvements in heart health among the rats that received these nanoparticles. Specifically, their heart function showed recovery, with important biochemical markers reflecting less damage. The lower dose of ZnO NPs was especially effective, aiding the antioxidant system and boosting nitric oxide production, which is vital for heart function.
Our findings suggest that ZnO NPs could be a promising way to counteract the cardiotoxic effects of doxorubicin. This insight opens new avenues for treatment strategies aimed at patients who need chemotherapy without risking their heart health.
Throughout the research, we observed significant improvements in heart health among the rats that received these nanoparticles. Specifically, their heart function showed recovery, with important biochemical markers reflecting less damage. The lower dose of ZnO NPs was especially effective, aiding the antioxidant system and boosting nitric oxide production, which is vital for heart function.
Our findings suggest that ZnO NPs could be a promising way to counteract the cardiotoxic effects of doxorubicin. This insight opens new avenues for treatment strategies aimed at patients who need chemotherapy without risking their heart health.
8
Positive heart effect
Most Useful Review
The last time I purchased this supplement in gelatin capsules, I couldn't immediately discern the difference. I take it to support my heart, and I appreciate its effects. When I attempted to increase the dosage, my heartbeat became somewhat unsettled. I'm grateful to IHERB and all those who contribute reviews; it significantly aids in supplement selection, as doctors aren't always reliably knowledgeable.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9.5
Sore throat relief
Most Useful Review
The quality is decent, the portion is generous, and the ingredients are ample. After taking one tablet daily, I’ve noticed a significant reduction in my sore throat.
Chest Pain details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
9
We delved into an intriguing question: Can high doses of zinc help relieve chest pain caused by angina pectoris? Our research reviewed studies that highlight how zinc may play a role in managing this condition. Angina pectoris often results from arteriosclerosis, where the arteries become narrowed due to cholesterol buildup and other factors.
We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.
Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.
Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.
Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.
Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
9.5
Eliminated stomach pain
Most Useful Review
I purchased this for a family member who suffers from stomach pain when hungry. Since beginning the treatment, I've not experienced any stomach pain while feeling hungry, so I will continue with it. At present, I opt for a slightly cheaper brand from iHerb, but this manufacturer's product was also satisfactory.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.8
9
Zinc supplementation benefits MS models
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
8.8
Improved skin condition
Most Useful Review
Great product! My skin improved significantly. The zinc dosage is just right, causing no nausea. Although the capsule shell is noticeable, it is easy to swallow. I've noticed a marked improvement in my skin, especially with acne, which has reduced considerably. I'm hopeful for further benefits regarding my autoimmune disorder. I will order more and highly recommend it!
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.5
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.2
9.5
We set out to explore how zinc oxide nanoparticles (ZnO NPs) could help control the bacteria responsible for food poisoning in raw chicken meat. Our approach involved integrating these nanoparticles into packaging materials to see if they could effectively inactivate Campylobacter jejuni, a common and concerning pathogen in poultry.
Through our experiments, we discovered that immobilizing ZnO NPs in functional pads placed under raw chicken could dramatically reduce bacterial counts. In fact, we saw a reduction from about 4 log CFU to an undetectable level within just three days when storing chicken at 4°C. Notably, we monitored zinc levels in the chicken meat, confirming a safe release of zinc without any migration of nanoparticles onto the food. This means that we can help keep raw chicken safe and fresh without compromising its integrity or quality.
Not only did we find that these functional pads inactivated the harmful bacteria, but we also noted a related increase in lactic acid production, which plays a role in further protecting the meat. Our findings open up new avenues for using zinc in food packaging, offering a way to enhance food safety without directly adding chemicals to the food itself. Overall, this study highlights the potential for nanotechnology to play a significant role in managing foodborne pathogens like Campylobacter in poultry products.
Through our experiments, we discovered that immobilizing ZnO NPs in functional pads placed under raw chicken could dramatically reduce bacterial counts. In fact, we saw a reduction from about 4 log CFU to an undetectable level within just three days when storing chicken at 4°C. Notably, we monitored zinc levels in the chicken meat, confirming a safe release of zinc without any migration of nanoparticles onto the food. This means that we can help keep raw chicken safe and fresh without compromising its integrity or quality.
Not only did we find that these functional pads inactivated the harmful bacteria, but we also noted a related increase in lactic acid production, which plays a role in further protecting the meat. Our findings open up new avenues for using zinc in food packaging, offering a way to enhance food safety without directly adding chemicals to the food itself. Overall, this study highlights the potential for nanotechnology to play a significant role in managing foodborne pathogens like Campylobacter in poultry products.
2.5
Severe reactions
Most Useful Review
My husband felt weak and vomited shortly after taking the pill with food. I tried half a pill on a full stomach, but I experienced a strong reaction to the high dosage, possibly leading to food poisoning.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.8
8
This study examined the effectiveness of a nutritional supplement containing zinc, among other ingredients, in preventing the recurrence of benign paroxysmal positional vertigo (BPPV), a condition that can cause intense dizziness. We followed a diverse group of 128 patients with a history of frequent BPPV episodes. They were divided into three groups based on their vitamin D levels and received different treatment plans.
In one group, those with low vitamin D received a daily supplement containing zinc, along with other antioxidants and vitamin D3. We noticed a remarkable decrease in BPPV relapses in this group after six months compared to where they started. However, for the groups that had sufficient vitamin D and particularly those receiving zinc without vitamin D, we did not find significant benefits in reducing dizziness recurrence.
While zinc was part of a combined treatment approach, it didn’t demonstrate a standalone positive impact on dizziness. Our findings suggest that while zinc might play a role alongside other supplements, it shouldn't be solely relied upon for preventing BPPV relapses in patients with sufficient vitamin D levels.
In one group, those with low vitamin D received a daily supplement containing zinc, along with other antioxidants and vitamin D3. We noticed a remarkable decrease in BPPV relapses in this group after six months compared to where they started. However, for the groups that had sufficient vitamin D and particularly those receiving zinc without vitamin D, we did not find significant benefits in reducing dizziness recurrence.
While zinc was part of a combined treatment approach, it didn’t demonstrate a standalone positive impact on dizziness. Our findings suggest that while zinc might play a role alongside other supplements, it shouldn't be solely relied upon for preventing BPPV relapses in patients with sufficient vitamin D levels.
0
Over dosage issues
Most Useful Review
The dosage was too high! It made me very ill, and I discovered that taking over 40mg daily isn’t advisable, as this contains 50mg. I experienced extreme nausea and dizziness. However, these are tablets, so I plan to cut them into quarters.
