SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 18 Reviews
8.2
Supplement Facts
Serving Size:  1 Tablet
Serving Per Container:  275
Amount Per Serving
%DV
Total Carbohydrates
1 g
<1%**
Calcium (as Calcium Carbonate)
98 mg
8%
Proprietary BlendCascara Sagrada powder (bark), Fennel powder (seed), Psyllium powder (seed husk), Ginger powder (rhizome), Acacia Gum, Barley Grass powder (aerial), Beet powder (root), Glucomannan, Karaya Gum, Lemon Peel powder (peel), Oat Bran powder, Peppermint powder (leaf), Red Raspberry (Rubus idaeus) powder (leaf), Slippery Elm powder (bark), Chlorella powder, Guar Gum, Lactobacillus acidophilus (1 million/g *** )
542 mg

Top Medical Research Studies

9
Lactobacillus drink benefits IBS-C
Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink.
High relevance for IBS treatment
We explored the impact of a Lactobacillus-containing cultured milk drink on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants consumed this drink daily while we assessed their clinical symptoms and inflammatory markers.

Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Read More
9
Probiotics improve IBS symptoms
DDS-1 and UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial.
Strong relevance to IBS treatment
This study looked into the effects of two probiotic strains, DDS-1 and UABla-12, on alleviating abdominal pain and other IBS symptoms.

We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.

Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.

Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
Read More
8
Probiotics show promise for IBS relief
Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study.
Study confirms probiotics’ relevance
We evaluated the efficacy of quadruple-coated probiotics in patients with irritable bowel syndrome (IBS). One hundred and nine participants were randomly assigned to either the probiotic or placebo group for four weeks.

Participants recorded their symptoms, and we noted a significant improvement in overall IBS symptoms, particularly in female and constipation-predominant patients. The results were promising, suggesting that these probiotics can provide relief. However, further studies are needed to explore why women respond differently to this treatment.
Read More

Most Useful Reviews

9.5
Effective for constipation
The intestines have responded to two pills, but hydration is crucial. I suffered from severe constipation, going three days without a bowel movement despite normal tests. My intestines were weak, so I tried this product. The manufacturer claimed I could achieve 2-3 bowel movements daily. I began with one tablet morning and evening, and the effect was noticeable after two daily tablets. I found relief and plan to increase my dose slightly at night. It is essential to drink plenty of water with the pill and throughout the day – at least eight glasses. Initially, I neglected my water intake and felt unwell, but after hydrating properly, everything normalised. The effect is remarkable; I'm truly satisfied with the results. The tablets are small, green, and easy to swallow. I wholeheartedly recommend them.
Read More
9.5
Highly recommended supplement
I tried this for the first time and it works wonderfully. The composition is impressive, and it has a pleasant licorice smell. I take one in the morning and one at night, and I highly recommend this supplement.
Read More
9.5
Restores gut health
After using many bottles, the stress surrounding my bowel movements is gone. Other detox supplements I tried didn't work. Once this ColonCleanse arrived, my intestinal condition improved. Individual differences exist, but I plan to keep using it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
  • All Researches
9.5
Effective probiotic IBS treatment
Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial.
High relevance for IBS management
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.

Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
Read More
9.5
Effective probiotic IBS treatment
Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial.
High relevance for IBS management
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.

Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
Read More
9
Lactobacillus drink benefits IBS-C
Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink.
High relevance for IBS treatment
We explored the impact of a Lactobacillus-containing cultured milk drink on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants consumed this drink daily while we assessed their clinical symptoms and inflammatory markers.

Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Read More
9
Probiotics improve IBS symptoms
DDS-1 and UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial.
Strong relevance to IBS treatment
This study looked into the effects of two probiotic strains, DDS-1 and UABla-12, on alleviating abdominal pain and other IBS symptoms.

We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.

Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.

Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
Read More
8
Lactobacillus aids IBS-related depression
A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome.
Probiotic intervention relevance confirmed
We examined how consuming a cultured milk drink with Lactobacillus acidophilus might impact depression in patients with irritable bowel syndrome (IBS). The study involved 110 participants who were divided into groups to receive either the probiotic drink or a placebo over 12 weeks.

Those with subthreshold depression experienced significant reductions in depression scores. The probiotic group even saw boosts in serotonin levels and improvements in quality of life. Although everyone reported reduced IBS severity, the probiotics specifically showed notable potential in managing depressive symptoms linked to IBS.
Read More

User Reviews

USERS' SCORE
Good
Based on 18 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Effective for constipation
The intestines have responded to two pills, but hydration is crucial. I suffered from severe constipation, going three days without a bowel movement despite normal tests. My intestines were weak, so I tried this product. The manufacturer claimed I could achieve 2-3 bowel movements daily. I began with one tablet morning and evening, and the effect was noticeable after two daily tablets. I found relief and plan to increase my dose slightly at night. It is essential to drink plenty of water with the pill and throughout the day – at least eight glasses. Initially, I neglected my water intake and felt unwell, but after hydrating properly, everything normalised. The effect is remarkable; I'm truly satisfied with the results. The tablets are small, green, and easy to swallow. I wholeheartedly recommend them.
Read More
9.5
Highly recommended supplement
I tried this for the first time and it works wonderfully. The composition is impressive, and it has a pleasant licorice smell. I take one in the morning and one at night, and I highly recommend this supplement.
9.5
Restores gut health
After using many bottles, the stress surrounding my bowel movements is gone. Other detox supplements I tried didn't work. Once this ColonCleanse arrived, my intestinal condition improved. Individual differences exist, but I plan to keep using it.
9.5
Smooth operation
This product works smoothly without causing any stomach pain. I've achieved regular bowel movements, and honestly, what more could I ask for?
8.8
Awesome bowel benefits
This product is of excellent quality! I take it before meals along with Inulin, three pills roughly an hour prior. The benefits for bowel movement, intestinal transit, and constipation are remarkable. The pills are tasteless and easy to swallow, and I strongly recommend it!

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