We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Read More
9
Zinc gel aids cold sore healing
[Clinical double-blind trial of topical zinc sulfate for herpes labialis recidivans].
We conducted a double-blind, placebo-controlled clinical trial to assess the impact of zinc sulfate gel on cold sores, specifically herpes labialis recidivans. In our study, patients treated with zinc sulfate gel, known as Virudermin Gel, experienced significantly reduced symptoms and faster healing compared to those who received just the gel without zinc.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
Read More
8
Zinc treatment helps cold sores
Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.
We aimed to understand how zinc might affect the occurrence and duration of cold sores, also known as herpes labialis. In our study, we treated 20 patients, mostly women with an average age of 26.6, who experienced more than six episodes of cold sores each year. They received zinc sulphate at a dose of 22.5 mg twice daily during specific months over a year while we monitored their symptoms for 12 months.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
Read More
Most Useful Reviews
9
Effective against skin issues
21 people found this helpful
Zinc acts as a powerful antioxidant, vital for immunity and skin health. It helps with cold sores and oily skin by reducing inflammation and sebum production. For colds, I combine zinc with vitamin C and have noticed significant benefits over the years; my children rarely miss school due to illness. It seems to enhance overall resistance during seasonal sickness.
Read More
9
Prevents cold sores
18 people found this helpful
This zinc is effective for preventing colds and cold sores. My friends and I use it alongside other supplements for herpes prevention, with notable outcomes. Since changing to this zinc chelate, I’ve seen a reduction in outbreaks, improving our health immensely. The results are promising, and I encourage others to try it as well.
Read More
9
Winter immunity boost
14 people found this helpful
I'm pleased to say that with this zinc, my family has survived winter without a cold. We combine it with vitamin D and C, taking it post-meal to avoid nausea. While others suffer from illness, this zinc has effectively helped us stay healthy. I wish the same for others!
We explored the connection between zinc levels and recurrent herpes labialis (RHL), commonly known as cold sores. In a study involving 80 individuals, we compared the salivary zinc levels of healthy people with those experiencing RHL during both the acute and convalescent phases.
The findings revealed that patients in the acute phase had significantly lower zinc levels (160.8 ng/ml) compared to when they were recovering (205.7 ng/ml). Both those phases showed lower zinc levels than the healthy individuals' average. This suggests that zinc levels are not just lower when cold sores are present, but also improve after the lesions heal.
Our results indicate that maintaining adequate zinc levels might be beneficial for people suffering from cold sores. Incorporating zinc supplements could play a role in both treating and preventing these uncomfortable outbreaks. We found that increasing serum zinc might help RHL patients, shedding light on a potential supportive treatment strategy for cold sores.
Read More
9
Zinc may relieve cold sores
Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes.
We conducted a small pilot study to investigate how a combination of L-lysine, zinc, and herbal ingredients could help treat cold sores caused by the Herpes simplex virus. Our goal was to observe the changes in symptoms such as itching, burning, and soreness among participants over the course of treatment.
Thirty individuals, split evenly between genders, participated in our open-label study. We monitored their symptoms through various methods, including self-reported outcomes, photographs, and daily diaries. By the sixth day of treatment, most participants showed considerable improvement, with some experiencing full resolution of their symptoms.
While we didn't isolate the effect of zinc alone, its inclusion in the treatment mix seems promising. By the end of our study, we found that 87 percent of participants had improved symptomatically, which indicates that the combination treatment may effectively relieve cold sore symptoms. Importantly, no adverse effects were reported during the study, which adds to our understanding of these treatments' safety.
Read More
9
Zinc cream alleviates cold sores
A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine.
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Read More
9
Zinc gel aids cold sore healing
[Clinical double-blind trial of topical zinc sulfate for herpes labialis recidivans].
We conducted a double-blind, placebo-controlled clinical trial to assess the impact of zinc sulfate gel on cold sores, specifically herpes labialis recidivans. In our study, patients treated with zinc sulfate gel, known as Virudermin Gel, experienced significantly reduced symptoms and faster healing compared to those who received just the gel without zinc.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
Read More
8
Pomegranate extract reduces inflammation
Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin.
We examined how the combination of pomegranate rind extract (PRE) and zinc impacts cold sores, particularly focusing on inflammation. By applying these substances to ex vivo porcine skin, we were able to assess their ability to modulate COX-2, a key player in the inflammation process.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
Zinc acts as a powerful antioxidant, vital for immunity and skin health. It helps with cold sores and oily skin by reducing inflammation and sebum production. For colds, I combine zinc with vitamin C and have noticed significant benefits over the years; my children rarely miss school due to illness. It seems to enhance overall resistance during seasonal sickness.
Read More
9
Prevents cold sores
18 people found this helpful
This zinc is effective for preventing colds and cold sores. My friends and I use it alongside other supplements for herpes prevention, with notable outcomes. Since changing to this zinc chelate, I’ve seen a reduction in outbreaks, improving our health immensely. The results are promising, and I encourage others to try it as well.
Read More
9
Winter immunity boost
14 people found this helpful
I'm pleased to say that with this zinc, my family has survived winter without a cold. We combine it with vitamin D and C, taking it post-meal to avoid nausea. While others suffer from illness, this zinc has effectively helped us stay healthy. I wish the same for others!
Read More
9
Reduced herpes incidence
5 people found this helpful
It helped with cold sores. I take a jar during the season. I used to suffer from colds and herpes, but now it’s much less frequent. The chelated form is very effective. I recommend it.
Read More
9
Improved skin health
4 people found this helpful
I initially used zinc for skin papillomas based on a doctor’s advice. After switching to zinc chelate, I noticed a significant improvement over two months, and my cold sore occurrences diminished. Incorporating physical activity and good hydration may have also contributed. Overall, I feel healthier now.
Cold sores, also known as fever blisters, are small, fluid-filled blisters that typically appear on or around the lips, although they can also occur in other areas of the face. They are caused by the herpes simplex virus (HSV), primarily HSV-1, and are highly contagious. The initial outbreak may be accompanied by symptoms such as fever, swollen lymph nodes, and a general feeling of malaise. Once infected, the virus remains dormant in the body and can reactivate, leading to recurring outbreaks, often triggered by stress, illness, or exposure to sunlight.
Treatment options for cold sores often focus on alleviating symptoms and speeding up healing. Over-the-counter creams containing antiviral medication like docosanol can help reduce the duration of an outbreak when applied early on. Prescription medications may be recommended for more severe cases. Home remedies, such as applying ice, using aloe vera, or taking lysine supplements, may also offer some relief. Prevention strategies include avoiding known triggers and practicing good hygiene, like not sharing utensils or personal items with infected individuals.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc is often touted as a potential remedy for cold sores, primarily due to its immune-boosting properties and its role in skin health. Research suggests that zinc may help reduce the severity and duration of cold sore outbreaks, as it can inhibit the replication of the herpes simplex virus, the virus responsible for cold sores. It is available in various forms, including topical ointments and oral supplements. When applied directly to the affected area, zinc oxide or zinc sulfate creams may help soothe the skin and promote healing.
However, it's important to note that while zinc may aid in managing cold sores, it is not a cure. Results can vary from person to person, and some may find topical treatments to be more effective than others. Always consult a healthcare professional before starting any new treatment regimen, as they can provide guidance tailored to your specific situation. Additionally, maintaining a healthy lifestyle, including proper nutrition and stress management, can further support your immune system in preventing and managing outbreaks effectively.
Based on user reviews, the timeline for seeing results from taking zinc supplements for cold sores can vary. Several users report noticing a reduction in outbreaks and improvement in symptoms within just a few days of starting the supplement. For instance, one user mentioned that after taking zinc at the first hint of a cold, their symptoms disappeared within three days Read Review. Another user saw a significant decrease in cold sore occurrences and felt healthier after about two months Read Review.
It's important to note that while many users found zinc effective, experiences can differ. Some have mentioned seeing noticeable improvements when combining zinc with other vitamins, like vitamin C Read Review. Overall, users suggest that zinc can help manage and reduce the frequency of cold sores, but the time frame for results may range from a few days to a couple of months, depending on individual health and the timing of the supplement relative to symptoms.
The research surrounding zinc's effectiveness for cold sores reveals a varied landscape of findings. Some studies indicate that zinc may play a role in reducing both the frequency and duration of cold sore outbreaks, especially when administered as zinc sulfate. One study observed that patients taking zinc sulfate reported fewer outbreaks and quicker recovery times, averaging less than four occurrences per year with a shortened duration of 5.7 days [5]. However, the overall consensus suggests that while zinc might provide some benefits, it is often most effective when used in conjunction with other treatments, such as antiviral medications [4].
Topical applications of zinc, such as in zinc oxide or zinc sulfate gels, have demonstrated promising results in reducing the severity and duration of symptoms when applied promptly at the onset of a cold sore [7][8]. For instance, subjects using a zinc oxide/glycine cream experienced a significant reduction in healing time compared to those using a placebo. However, it’s noteworthy that many studies highlight the importance of combining zinc treatments with more potent anti-inflammatory agents to enhance their overall effectiveness, particularly when addressing the inflammatory responses associated with cold sores [2]. Thus, while zinc shows potential, it's advisable to approach its use as part of a broader strategy for managing cold sore symptoms.
Users have consistently reported improvements in their health after incorporating zinc supplements into their routines, particularly regarding colds and cold sores. Many have shared that taking zinc at the onset of symptoms often leads to rapid relief. For instance, one user noted that their cold symptoms vanished within three days after starting zinc alongside vitamin C Read Review. Another review highlighted a family’s success in avoiding colds throughout winter when combining zinc with other vitamins Read Review. Additionally, users have mentioned significant reductions in cold sore outbreaks after switching to a chelated form of zinc, emphasizing its effective absorption and benefits to overall health Read Review.
Anecdotal experiences suggest that the integration of zinc can lead to both fewer and less severe colds. For example, multiple users pointed out that by taking zinc promptly when feeling ill, they experienced quicker recovery and milder symptoms compared to previous illnesses Read Review. While results vary among individuals—some even report improved skin health and immunity—many appear to find success when combining zinc with other supplements like vitamin C and vitamin D Read Review. Overall, these user reviews indicate that zinc can be a valuable addition to managing health, particularly during cold season.
Users report positive experiences when combining zinc supplements with other vitamins for managing cold sores and colds. Many have found that taking zinc alongside vitamin C significantly enhances its effectiveness, often resulting in quicker recovery times and a decrease in cold sore outbreaks. For example, one user noted that after taking zinc and vitamin C at the first sign of a cold, symptoms disappeared within three days Read Review. Others have reported similar benefits when combining zinc with vitamin D, indicating a comprehensive approach to winter immunity Read Review.
Additionally, users have praised the chelated form of zinc for its enhanced absorption and effectiveness. One reviewer highlighted that transitioning to zinc chelate led to reduced outbreak frequency and improved overall health Read Review. Combining zinc with supplements like monolaurin and turmeric was also noted to produce promising results in mitigating cold symptoms Read Review. Overall, users advocate for a multi-supplement approach involving zinc, emphasizing its potential to bolster health outcomes during cold and flu season.
When it comes to effectively treating cold sores, zinc might be worth considering, particularly in certain forms and dosages. Research indicates that zinc sulfate can make a notable difference in managing symptoms and reducing the frequency of outbreaks. In a study that provided zinc sulfate at a dosage of 22.5 mg twice daily, participants experienced a significant decrease in cold sore occurrences, averaging fewer than four episodes per year, with an average duration of approximately 5.7 days per outbreak [5]. This suggests that maintaining adequate zinc levels, possibly through supplementation, might help those who suffer from recurrent cold sores.
Moreover, topical zinc formulations, such as zinc oxide or zinc sulfate gels, have also shown promise. In one controlled trial, patients who began treatment within 24 hours of symptom onset noted a reduction in the duration of their cold sore lesions, averaging 5 days compared to 6.5 days for those on a placebo [7]. While the optimal dose may vary based on individual health and specific formulations, the combination of systemic supplementation and topical applications can offer a comprehensive strategy for those looking to alleviate the discomfort associated with cold sores.
9
Helps with cold symptoms
5 people found this helpful
I took zinc at the first hint of a cold together with vitamin C. Within three days, there were no symptoms. As someone who suffers from sinusitis, I found it helpful to take it after meals to avoid nausea. This zinc has become a must-have for me during cold season!
9
Improved skin health
4 people found this helpful
I initially used zinc for skin papillomas based on a doctor’s advice. After switching to zinc chelate, I noticed a significant improvement over two months, and my cold sore occurrences diminished. Incorporating physical activity and good hydration may have also contributed. Overall, I feel healthier now.
7.5
Improved recovery speed
230 people found this helpful
In light of my health issues, including primary immunodeficiency and dermatitis, I've found zinc helpful. It supports my immune system during winter viruses and low temperatures. The results have been positive; I noticed that a recent illness was milder and my skin improved, with fewer cold sores. It’s crucial to take zinc with consideration of its interaction with other supplements. This brand has suited me well.
9
Winter immunity boost
14 people found this helpful
I'm pleased to say that with this zinc, my family has survived winter without a cold. We combine it with vitamin D and C, taking it post-meal to avoid nausea. While others suffer from illness, this zinc has effectively helped us stay healthy. I wish the same for others!
9
Reduced herpes incidence
5 people found this helpful
It helped with cold sores. I take a jar during the season. I used to suffer from colds and herpes, but now it’s much less frequent. The chelated form is very effective. I recommend it.
9
Cold prevention aid
1 people found this helpful
Just one capsule a day, and I can forget about a cold. If I do catch one, I double the dose, and my cold disappears quicker and is less severe.
9
Prevents cold sores
18 people found this helpful
This zinc is effective for preventing colds and cold sores. My friends and I use it alongside other supplements for herpes prevention, with notable outcomes. Since changing to this zinc chelate, I’ve seen a reduction in outbreaks, improving our health immensely. The results are promising, and I encourage others to try it as well.
7.5
Quick recovery from colds
1 people found this helpful
I love this zinc for its price and quality. It’s my first choice for colds, taken with vitamin C. When I caught a nasty virus with a high fever, I used it alongside monolaurin and vitamin C and felt better in just two days. The chelated form has optimal absorption.
8
Zinc treatment helps cold sores
Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.
We aimed to understand how zinc might affect the occurrence and duration of cold sores, also known as herpes labialis. In our study, we treated 20 patients, mostly women with an average age of 26.6, who experienced more than six episodes of cold sores each year. They received zinc sulphate at a dose of 22.5 mg twice daily during specific months over a year while we monitored their symptoms for 12 months.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
We explored the effectiveness of zinc treatments for cold sores, often caused by the herpes simplex virus. The research indicates that using zinc oxide or zinc sulfate, along with other interventions such as anesthetic or antiviral creams, can lead to a slight reduction in the duration of symptoms when applied promptly. However, its benefits appear small and may not outweigh other treatments available.
The study also highlighted the potential of oral antiviral medications in managing symptoms and preventing future outbreaks. While zinc treatment may offer some help, it is essential to understand that it is usually most effective when used alongside other therapies. As for using sunscreen to avoid triggers like sunlight, the results were mixed. In controlled settings, some protections were noted, but these weren't consistently replicated in everyday situations.
All in all, prompt treatment with either topical or oral medications is key for alleviating cold sore symptoms. We found that both approaches can help prevent future occurrences of cold sores, but we should be cautious in relying solely on zinc as a treatment option.
9
Zinc cream alleviates cold sores
A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine.
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9
Zinc gel aids cold sore healing
[Clinical double-blind trial of topical zinc sulfate for herpes labialis recidivans].
We conducted a double-blind, placebo-controlled clinical trial to assess the impact of zinc sulfate gel on cold sores, specifically herpes labialis recidivans. In our study, patients treated with zinc sulfate gel, known as Virudermin Gel, experienced significantly reduced symptoms and faster healing compared to those who received just the gel without zinc.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
8
Pomegranate extract reduces inflammation
Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin.
We examined how the combination of pomegranate rind extract (PRE) and zinc impacts cold sores, particularly focusing on inflammation. By applying these substances to ex vivo porcine skin, we were able to assess their ability to modulate COX-2, a key player in the inflammation process.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
References
Ranjbar Z, Zahed M, Ranjbar MA, Shirmardan Z. Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals. BMC Oral Health. 2020;20:296. doi:10.1186/s12903-020-01277-2
Houston DM, Bugert J, Denyer SP, Heard CM. Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin. Eur J Pharm Biopharm. 2017;112:30. doi:10.1016/j.ejpb.2016.11.014
Khozeimeh F, Jafari N, Attar AM, Jafari S, Ataie M. Comparative analysis of salivary zinc level in recurrent herpes labialis. Dent Res J (Isfahan). 2012;9:19. doi:10.4103/1735-3327.92922
Opstelten W, Neven AK, Eekhof J. Treatment and prevention of herpes labialis. Can Fam Physician. 2008;54:1683.
Femiano F, Gombos F, Scully C. Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy. J Oral Pathol Med. 2005;34:423.
Singh BB, Udani J, Vinjamury SP, Der-Martirosian C, Gandhi S, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10:123.
Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Altern Ther Health Med. 2001;7:49.
Kneist W, Hempel B, Borelli S. [Clinical double-blind trial of topical zinc sulfate for herpes labialis recidivans]. Arzneimittelforschung. 1995;45:624.
Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Dermatol. 1981;104:191.