Last update
3/14/2026
Research Authors

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Zinc (as Zinc bisglycinate)
30 mg
273%
📅 Last updated:

Top Medical Research Studies

9
Zinc oxide mitigates diarrhea impacts
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.

Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.

In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More

Most Useful Reviews

0
Diarrhea intolerance
1 people found this helpful
This zinc chelate caused me diarrhoea, and I could not tolerate it. Unfortunately, it doesn't seem to provide any benefits either.
Read More
9
No side effects
Chelated zinc is the most bioavailable form of this mineral. It is readily absorbed in the intestines and does not cause side effects like nausea, vomiting, or diarrhoea.
Read More
0
Sensitive intestines
This zinc caused me diarrhoea due to my sensitive intestines.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
9
Zinc oxide mitigates diarrhea impacts
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.

Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.

In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Diarrhea intolerance
1 people found this helpful
This zinc chelate caused me diarrhoea, and I could not tolerate it. Unfortunately, it doesn't seem to provide any benefits either.
Read More
9
No side effects
Chelated zinc is the most bioavailable form of this mineral. It is readily absorbed in the intestines and does not cause side effects like nausea, vomiting, or diarrhoea.
Read More
0
Sensitive intestines
This zinc caused me diarrhoea due to my sensitive intestines.
Read More
7.5
Helps immunity
I ordered zinc for my children during diarrhoea and to help boost their immunity. I don’t regret it.
Read More

Frequently Asked Questions

7.5
Helps immunity
I ordered zinc for my children during diarrhoea and to help boost their immunity. I don’t regret it.
0
Sensitive intestines
This zinc caused me diarrhoea due to my sensitive intestines.
9
No side effects
Chelated zinc is the most bioavailable form of this mineral. It is readily absorbed in the intestines and does not cause side effects like nausea, vomiting, or diarrhoea.
9
Zinc oxide mitigates diarrhea impacts
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.

Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.

In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.

References

  1. Zhang Y, Liu J, Li M, Dong Y, Li Z, et al. Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance. Vet Sci. 2025;12. 10.3390/vetsci12020115
Data last updated:
image