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Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Milk Thistle extract (seed) standardized to 80% silymarin (140 mg)
175 mg
**
The product is found useful for the following medical conditions
Hepatitis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.8
9.5
Therapeutic benefits
Most Useful Review
This product is incredibly safe and offers unmatched protection for the liver. Clinical studies indicate that standardized milk thistle, particularly in doses of around 600 mg, can improve conditions such as alcohol-related liver disease, hepatitis, and liver cirrhosis over 8-12 weeks. It’s essential to consult a physician before use, but this product is both beneficial and safe while taking prescriptions.
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.7
9
Silybin shows promise for autoimmune disorders
Silybin Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Dendritic Cell Activation and Th17 Cell Differentiation.
Most Relevant Research
We investigated how silybin, a unique flavonoid found in certain plants, impacts autoimmune disorders, specifically using a model for multiple sclerosis called experimental autoimmune encephalomyelitis (EAE).
In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.
The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.
In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.
The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.
9.5
Liver enzyme improvement
Most Useful Review
V.E. Thiessen (retired businessman) found this product to achieve what no prescription could for my wife. She has an autoimmune disorder and has undergone a liver transplant, with persistent high liver enzymes. Since using milk thistle, we've seen them return to normal, much to the transplant team's surprise. Thisilyn, supplied by iHerb, is our preferred choice. The service is always quick and reliable.
Acne details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Silybum marianum reduces acne severity
Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention.
Most Relevant Research
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
9.5
Cleared back acne
Most Useful Review
Cured acne on back. This product helped clear up acne on my back. I am very pleased with it and will be purchasing more.
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 1 Review
8.6
9
Silibinin shows promise for asthma
Silibinin attenuates allergic airway inflammation in mice.
Most Relevant Research
We examined how silibinin, a compound found in milk thistle, affects allergic asthma in a mouse model. Our findings showed that silibinin significantly helped reduce airway inflammation and hyperresponsiveness, mainly by targeting the NF-κB pathway. This suggests that silibinin might offer protective benefits against allergic airway conditions by moderating inflammatory responses. While our research found promising results in mice, further studies are necessary to confirm its effectiveness in human asthma treatment.
9.5
Cures allergies
Most Useful Review
This has significantly helped my allergies. I initially purchased it for cellulite, but while I haven't noticed changes, it genuinely cures my awful allergies. Although I still take other allergy medications, these have been more effective than Mucinex-D when taken three times a day. They have transformed my allergy experience, and I plan to use them for life. If you struggle with allergies and find no relief from synthetic medications, I highly recommend trying milk thistle; it’s fantastic!
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.6
8
Silymarin shows anti-arthritis potential
Anti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase.
Most Relevant Research
We evaluated the anti-inflammatory and anti-arthritic properties of silymarin, derived from the Silybum marianum plant. In our study, we found that silymarin significantly reduced inflammation and arthritis symptoms in rat models. The research suggests that this effect occurs through the inhibition of a specific enzyme, 5-lipoxygenase.
While these results showcase the potential of silymarin, it's important to note that further research is needed to fully understand its effectiveness in humans.
While these results showcase the potential of silymarin, it's important to note that further research is needed to fully understand its effectiveness in humans.
9.5
Significant reduction
Most Useful Review
My Miracle Drug. Milk Thistle has significantly reduced my arthritis. I take two every morning and two every afternoon. I recommend organic Milk Thistle. I love this stuff.
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 66 Reviews
8.5
9
Silymarin improves liver protection
Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress.
Most Relevant Research
We investigated the effects of silymarin on liver and heart health under oxidative stress from paracetamol. In a controlled study with 28 male mice, silymarin showed a strong potential to reduce liver injury markers and improve liver enzyme levels after treatment.
Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.
Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.
9.5
Normalised liver enzymes
Most Useful Review
This product has helped my wife with liver disease more than any prescription drug. After her liver transplant, we struggled to manage high liver enzymes, but milk thistle significantly lowered them, surprising her transplant team.
High Cholesterol details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.4
9
Silymarin positively influences cholesterol
Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial.
Most Relevant Research
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
9.5
Maintains liver health
Most Useful Review
This product effectively keeps my blood tests clean and liver enzymes under control. I take pain medication for arthritis, which can be toxic, but using this product has had no detrimental effects on my liver.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.3
6.8
Improved metabolism
Most Useful Review
I felt the effects of the treatment on my liver almost immediately. Initially, I experienced some bone pain, but this subsided, and I noticed an improvement in my metabolism.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 14 Reviews
8.2
7.5
Positive changes noted
Most Useful Review
I’ve been taking this in hope of alleviating my chronic fatigue syndrome. As a vegetarian, I avoid alcohol and tobacco, yet I noticed a significant change; my lip colour brightened after a few days of use. I'm optimistic about continuing with this product.
Nausea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 1 Review
7.8
0.5
Formulation associated
Most Useful Review
I've used milk thistle for years, but this is the first formulation linked to nausea.
