5/20/2025
Last update
5/20/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from fish [liver] oil, retinyl palmitate)
3,000 mcg
333%
Top Medical Research Studies
9.5
We explored the effects of alitretinoin, a form of vitamin A, on chronic hand eczema (CHE). This powerful drug is known to target specific receptors in the skin, offering insights into its method of action. Through our detailed study, we examined skin samples from patients who responded well to alitretinoin treatment.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
Read More
9
Alitretinoin treatment effectiveness assessed
We examined the effectiveness of alitretinoin, a vitamin A derivative, for treating severe chronic hand eczema—especially for those who haven't found relief with strong topical steroids. In clinical trials, participants took alitretinoin daily for up to 24 weeks, and results showed a notable improvement in eczema severity and extent.
Many patients reported their hands becoming 'clear' or 'almost clear,' significantly more than those using a placebo. This exciting finding was consistent in real-world studies as well. Alitretinoin generally proved to be well tolerated, with most side effects being mild, manageable, and reversible.
Overall, we see that alitretinoin stands out as a valuable option for patients struggling with chronic hand eczema that doesn't respond to traditional treatments. It gives hope to individuals who have endured pain and discomfort due to this challenging condition.
Many patients reported their hands becoming 'clear' or 'almost clear,' significantly more than those using a placebo. This exciting finding was consistent in real-world studies as well. Alitretinoin generally proved to be well tolerated, with most side effects being mild, manageable, and reversible.
Overall, we see that alitretinoin stands out as a valuable option for patients struggling with chronic hand eczema that doesn't respond to traditional treatments. It gives hope to individuals who have endured pain and discomfort due to this challenging condition.
Read More
9
We explored the therapeutic potential of alitretinoin, a form of vitamin A, for treating severe chronic hand eczema (CHE). This condition is quite prevalent, impacting up to 10% of people, and it can significantly affect their quality of life.
Alitretinoin is the first systemic treatment approved in the European Union for cases of CHE that haven't responded to conventional topical therapies. Our review highlighted various aspects, including how the drug works in the body, its effectiveness, and safety profile.
Patients who participated in clinical trials reported both objective and subjective improvements in their symptoms, along with a notable enhancement in their quality of life. However, we must exercise caution with patients who have pre-existing health issues or women who could become pregnant.
Overall, the findings suggest that alitretinoin could be a valid treatment option for those struggling with severe CHE.
Alitretinoin is the first systemic treatment approved in the European Union for cases of CHE that haven't responded to conventional topical therapies. Our review highlighted various aspects, including how the drug works in the body, its effectiveness, and safety profile.
Patients who participated in clinical trials reported both objective and subjective improvements in their symptoms, along with a notable enhancement in their quality of life. However, we must exercise caution with patients who have pre-existing health issues or women who could become pregnant.
Overall, the findings suggest that alitretinoin could be a valid treatment option for those struggling with severe CHE.
Read More
Most Useful Reviews
9
Eczema reduced
17 people found this helpful
I am truly impressed with this vitamin! After suffering from eczema flare-ups on my face for a year, I found relief. I started taking vitamin A about 20 days ago, and my face has improved 95%. It's been painless, and I even applied capsules directly to sore spots with noticeable healing within 48 hours. The fish oil's smell is worth the amazing results!
Read More
9
Eczema cleared quickly
Taking these capsules is very convenient. Within two weeks, my eczema vanished from my hands, allowing me to confidently have a manicure. I've saved money by not purchasing ointments from pharmacies.
Read More
7.5
Reduced eczema severity
I regularly use Vitamin A to assist with my skin condition and it has been beneficial in alleviating my eczema.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.4
- All Researches
9.5
We explored the effects of alitretinoin, a form of vitamin A, on chronic hand eczema (CHE). This powerful drug is known to target specific receptors in the skin, offering insights into its method of action. Through our detailed study, we examined skin samples from patients who responded well to alitretinoin treatment.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
Read More
9
We explored the therapeutic potential of alitretinoin, a form of vitamin A, for treating severe chronic hand eczema (CHE). This condition is quite prevalent, impacting up to 10% of people, and it can significantly affect their quality of life.
Alitretinoin is the first systemic treatment approved in the European Union for cases of CHE that haven't responded to conventional topical therapies. Our review highlighted various aspects, including how the drug works in the body, its effectiveness, and safety profile.
Patients who participated in clinical trials reported both objective and subjective improvements in their symptoms, along with a notable enhancement in their quality of life. However, we must exercise caution with patients who have pre-existing health issues or women who could become pregnant.
Overall, the findings suggest that alitretinoin could be a valid treatment option for those struggling with severe CHE.
Alitretinoin is the first systemic treatment approved in the European Union for cases of CHE that haven't responded to conventional topical therapies. Our review highlighted various aspects, including how the drug works in the body, its effectiveness, and safety profile.
Patients who participated in clinical trials reported both objective and subjective improvements in their symptoms, along with a notable enhancement in their quality of life. However, we must exercise caution with patients who have pre-existing health issues or women who could become pregnant.
Overall, the findings suggest that alitretinoin could be a valid treatment option for those struggling with severe CHE.
Read More
9
We explored the effectiveness of oral alitretinoin, a vitamin A derivative, for treating severe chronic hand eczema (CHE). With 631 patients participating in this observational study, we administered treatment for up to 24 weeks while monitoring outcomes in real-world conditions.
Our findings were encouraging; by the end of the study, nearly 30% of participants reported significant improvements in their conditions. Utilizing assessments such as the Physician Global Assessment and the EQ-5D quality of life questionnaire, we noted a clear enhancement in patients' overall well-being and work productivity. Notably, quality of life scores increased dramatically from baseline levels, indicating relief for many who suffer from this difficult skin condition.
Moreover, workplace impairment substantially reduced over the course of the study, suggesting that alitretinoin helps not only with the physical symptoms but also allows individuals to return to their daily activities more effectively. Although some patients reported adverse effects, these were generally manageable, and no new safety concerns arose throughout the study.
In summary, we observed that alitretinoin offers significant improvements for those grappling with severe CHE, enhancing both quality of life and ability to work.
Our findings were encouraging; by the end of the study, nearly 30% of participants reported significant improvements in their conditions. Utilizing assessments such as the Physician Global Assessment and the EQ-5D quality of life questionnaire, we noted a clear enhancement in patients' overall well-being and work productivity. Notably, quality of life scores increased dramatically from baseline levels, indicating relief for many who suffer from this difficult skin condition.
Moreover, workplace impairment substantially reduced over the course of the study, suggesting that alitretinoin helps not only with the physical symptoms but also allows individuals to return to their daily activities more effectively. Although some patients reported adverse effects, these were generally manageable, and no new safety concerns arose throughout the study.
In summary, we observed that alitretinoin offers significant improvements for those grappling with severe CHE, enhancing both quality of life and ability to work.
Read More
9
Alitretinoin treatment effectiveness assessed
We examined the effectiveness of alitretinoin, a vitamin A derivative, for treating severe chronic hand eczema—especially for those who haven't found relief with strong topical steroids. In clinical trials, participants took alitretinoin daily for up to 24 weeks, and results showed a notable improvement in eczema severity and extent.
Many patients reported their hands becoming 'clear' or 'almost clear,' significantly more than those using a placebo. This exciting finding was consistent in real-world studies as well. Alitretinoin generally proved to be well tolerated, with most side effects being mild, manageable, and reversible.
Overall, we see that alitretinoin stands out as a valuable option for patients struggling with chronic hand eczema that doesn't respond to traditional treatments. It gives hope to individuals who have endured pain and discomfort due to this challenging condition.
Many patients reported their hands becoming 'clear' or 'almost clear,' significantly more than those using a placebo. This exciting finding was consistent in real-world studies as well. Alitretinoin generally proved to be well tolerated, with most side effects being mild, manageable, and reversible.
Overall, we see that alitretinoin stands out as a valuable option for patients struggling with chronic hand eczema that doesn't respond to traditional treatments. It gives hope to individuals who have endured pain and discomfort due to this challenging condition.
Read More
8
We wanted to understand how vitamin A levels impact the severity of eczema in children. In our research, we analyzed clinical data from 159 children diagnosed with eczema, grouping them based on the severity of their condition—mild, moderate, and severe.
Throughout the study, we made some interesting observations. It became clear that as the severity of eczema increased, the levels of vitamin A declined significantly. We also noted a similar trend with vitamin D levels. Meanwhile, certain inflammatory markers such as TG2, IL-4, and IL-13 rose in correlation with worse symptoms.
This relationship was highlighted by our findings indicating a negative correlation between vitamin A and vitamin D levels and the severity of eczema, measured through SCORAD scores. This means as vitamin A levels dropped, the severity of eczema worsened, while increased inflammatory markers suggested intensifying symptoms.
After three months of treatment, all serum levels, including that of vitamin A, improved significantly across all groups. However, while vitamin A appears to be associated with the severity of eczema, we cannot conclude that vitamin A treatment alone effectively alleviates eczema symptoms, as no specific treatment effects were isolated during our analysis.
Overall, we believe that keeping an eye on vitamin A levels, along with these other markers, can give us valuable insights into eczema severity and treatment responses in children.
Throughout the study, we made some interesting observations. It became clear that as the severity of eczema increased, the levels of vitamin A declined significantly. We also noted a similar trend with vitamin D levels. Meanwhile, certain inflammatory markers such as TG2, IL-4, and IL-13 rose in correlation with worse symptoms.
This relationship was highlighted by our findings indicating a negative correlation between vitamin A and vitamin D levels and the severity of eczema, measured through SCORAD scores. This means as vitamin A levels dropped, the severity of eczema worsened, while increased inflammatory markers suggested intensifying symptoms.
After three months of treatment, all serum levels, including that of vitamin A, improved significantly across all groups. However, while vitamin A appears to be associated with the severity of eczema, we cannot conclude that vitamin A treatment alone effectively alleviates eczema symptoms, as no specific treatment effects were isolated during our analysis.
Overall, we believe that keeping an eye on vitamin A levels, along with these other markers, can give us valuable insights into eczema severity and treatment responses in children.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eczema reduced
17 people found this helpful
I am truly impressed with this vitamin! After suffering from eczema flare-ups on my face for a year, I found relief. I started taking vitamin A about 20 days ago, and my face has improved 95%. It's been painless, and I even applied capsules directly to sore spots with noticeable healing within 48 hours. The fish oil's smell is worth the amazing results!
Read More
9
Eczema cleared quickly
Taking these capsules is very convenient. Within two weeks, my eczema vanished from my hands, allowing me to confidently have a manicure. I've saved money by not purchasing ointments from pharmacies.
Read More
7.5
Reduced eczema severity
I regularly use Vitamin A to assist with my skin condition and it has been beneficial in alleviating my eczema.
Read More
Frequently Asked Questions
9
Eczema cleared quickly
Taking these capsules is very convenient. Within two weeks, my eczema vanished from my hands, allowing me to confidently have a manicure. I've saved money by not purchasing ointments from pharmacies.
9
We explored the effectiveness of oral alitretinoin, a vitamin A derivative, for treating severe chronic hand eczema (CHE). With 631 patients participating in this observational study, we administered treatment for up to 24 weeks while monitoring outcomes in real-world conditions.
Our findings were encouraging; by the end of the study, nearly 30% of participants reported significant improvements in their conditions. Utilizing assessments such as the Physician Global Assessment and the EQ-5D quality of life questionnaire, we noted a clear enhancement in patients' overall well-being and work productivity. Notably, quality of life scores increased dramatically from baseline levels, indicating relief for many who suffer from this difficult skin condition.
Moreover, workplace impairment substantially reduced over the course of the study, suggesting that alitretinoin helps not only with the physical symptoms but also allows individuals to return to their daily activities more effectively. Although some patients reported adverse effects, these were generally manageable, and no new safety concerns arose throughout the study.
In summary, we observed that alitretinoin offers significant improvements for those grappling with severe CHE, enhancing both quality of life and ability to work.
Our findings were encouraging; by the end of the study, nearly 30% of participants reported significant improvements in their conditions. Utilizing assessments such as the Physician Global Assessment and the EQ-5D quality of life questionnaire, we noted a clear enhancement in patients' overall well-being and work productivity. Notably, quality of life scores increased dramatically from baseline levels, indicating relief for many who suffer from this difficult skin condition.
Moreover, workplace impairment substantially reduced over the course of the study, suggesting that alitretinoin helps not only with the physical symptoms but also allows individuals to return to their daily activities more effectively. Although some patients reported adverse effects, these were generally manageable, and no new safety concerns arose throughout the study.
In summary, we observed that alitretinoin offers significant improvements for those grappling with severe CHE, enhancing both quality of life and ability to work.
8
Alitretinoin shows promise for eczema
We investigated the effectiveness of alitretinoin, a systemic retinoid related to vitamin A, in treating eczema in children and adolescents. This retrospective study involved chart reviews of patients under 18 years old who received alitretinoin at our pediatric skin center. The focus was to assess how well this treatment worked for chronic hand eczema and other inflammatory skin conditions.
Our results showed promising outcomes, with a noticeable improvement observed in many of the patients. Out of thirteen children treated, approximately 78% with chronic hand eczema displayed a moderate to excellent response after their treatment. The ages of these children ranged from 5.8 to 15.8 years, and they were suffering from conditions like severe atopic dermatitis and specific inherited ichthyoses.
We noted that while alitretinoin appeared safe, the most common side effect was headache, experienced by most patients, which led to treatment interruptions in a few cases. Overall, we can conclude that alitretinoin could be a strong option for treating pediatric eczema, especially for those who haven’t responded well to more conventional topical therapies. However, further research with larger groups will be necessary to confirm these findings and provide more comprehensive guidance.
Our results showed promising outcomes, with a noticeable improvement observed in many of the patients. Out of thirteen children treated, approximately 78% with chronic hand eczema displayed a moderate to excellent response after their treatment. The ages of these children ranged from 5.8 to 15.8 years, and they were suffering from conditions like severe atopic dermatitis and specific inherited ichthyoses.
We noted that while alitretinoin appeared safe, the most common side effect was headache, experienced by most patients, which led to treatment interruptions in a few cases. Overall, we can conclude that alitretinoin could be a strong option for treating pediatric eczema, especially for those who haven’t responded well to more conventional topical therapies. However, further research with larger groups will be necessary to confirm these findings and provide more comprehensive guidance.
9.5
We explored the effects of alitretinoin, a form of vitamin A, on chronic hand eczema (CHE). This powerful drug is known to target specific receptors in the skin, offering insights into its method of action. Through our detailed study, we examined skin samples from patients who responded well to alitretinoin treatment.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.
Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.
Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.
8
Effectiveness of alitretinoin in eczema
We set out to understand how oral alitretinoin, a form of vitamin A, can help patients suffering from severe chronic hand eczema that doesn’t respond to strong topical treatments. Our study involved a thorough analysis of medical records from 62 patients across 13 hospitals in various regions of Spain. We focused on those whose eczema had proven stubborn against typical therapies.
The findings showed that alitretinoin is often used at a consistent dosage of 30mg per day, and most dermatologists noted a satisfactory clinical response after just one treatment cycle. We also saw that the adverse effects reported were largely in line with what is expected from systemic retinoids, indicating a manageable safety profile.
Overall, dermatologists agreed that the benefits of using alitretinoin enhanced patient adherence to therapy and significantly improved their quality of life, allowing for a quicker return to everyday activities like work. While our research suggests that alitretinoin is effective, it is also important to note that we didn’t isolate its effects from other potential treatments.
The findings showed that alitretinoin is often used at a consistent dosage of 30mg per day, and most dermatologists noted a satisfactory clinical response after just one treatment cycle. We also saw that the adverse effects reported were largely in line with what is expected from systemic retinoids, indicating a manageable safety profile.
Overall, dermatologists agreed that the benefits of using alitretinoin enhanced patient adherence to therapy and significantly improved their quality of life, allowing for a quicker return to everyday activities like work. While our research suggests that alitretinoin is effective, it is also important to note that we didn’t isolate its effects from other potential treatments.
8
We wanted to understand how vitamin A levels impact the severity of eczema in children. In our research, we analyzed clinical data from 159 children diagnosed with eczema, grouping them based on the severity of their condition—mild, moderate, and severe.
Throughout the study, we made some interesting observations. It became clear that as the severity of eczema increased, the levels of vitamin A declined significantly. We also noted a similar trend with vitamin D levels. Meanwhile, certain inflammatory markers such as TG2, IL-4, and IL-13 rose in correlation with worse symptoms.
This relationship was highlighted by our findings indicating a negative correlation between vitamin A and vitamin D levels and the severity of eczema, measured through SCORAD scores. This means as vitamin A levels dropped, the severity of eczema worsened, while increased inflammatory markers suggested intensifying symptoms.
After three months of treatment, all serum levels, including that of vitamin A, improved significantly across all groups. However, while vitamin A appears to be associated with the severity of eczema, we cannot conclude that vitamin A treatment alone effectively alleviates eczema symptoms, as no specific treatment effects were isolated during our analysis.
Overall, we believe that keeping an eye on vitamin A levels, along with these other markers, can give us valuable insights into eczema severity and treatment responses in children.
Throughout the study, we made some interesting observations. It became clear that as the severity of eczema increased, the levels of vitamin A declined significantly. We also noted a similar trend with vitamin D levels. Meanwhile, certain inflammatory markers such as TG2, IL-4, and IL-13 rose in correlation with worse symptoms.
This relationship was highlighted by our findings indicating a negative correlation between vitamin A and vitamin D levels and the severity of eczema, measured through SCORAD scores. This means as vitamin A levels dropped, the severity of eczema worsened, while increased inflammatory markers suggested intensifying symptoms.
After three months of treatment, all serum levels, including that of vitamin A, improved significantly across all groups. However, while vitamin A appears to be associated with the severity of eczema, we cannot conclude that vitamin A treatment alone effectively alleviates eczema symptoms, as no specific treatment effects were isolated during our analysis.
Overall, we believe that keeping an eye on vitamin A levels, along with these other markers, can give us valuable insights into eczema severity and treatment responses in children.
References
- Li Y, Wang Z, Li X, Ma K, Shi Z. Changes and clinical significance of serum vitamin A, 25-(OH)D3, TG2, IL-4 and IL-13 levels in children with eczema. Arch Dermatol Res. 2025;317:375. 10.1007/s00403-025-03887-8
- Kislat A, Olah P, Kuchner M, Gerber PA, Schrader J, et al. The Endogenous Dual Retinoid Receptor Agonist Alitretinoin Exhibits Immunoregulatory Functions on Antigen-Presenting Cells. Int J Mol Sci. 2023;24. 10.3390/ijms24119654
- Napolitano M, Potestio L, De Lucia M, Nocerino M, Fabbrocini G, et al. Alitretinoin for the treatment of severe chronic eczema of the hands. Expert Opin Pharmacother. 2022;23:159. 10.1080/14656566.2021.1998457
- Luchsinger I, Vogler T, Schwieger-Briel A, Knöpfel N, Wälchli R, et al. Safe and effective use of alitretinoin in children with recalcitrant hand eczema and other dermatoses - a retrospective analysis. J Eur Acad Dermatol Venereol. 2020;34:1037. 10.1111/jdv.16088
- Yatsyna IV, Istomin AV, Pogozheva AV, Saarkoppel LM. [Using of specialized food for the workers with skin occupational eczema of perlite production]. Vopr Pitan. 2018;87:45. 10.24411/0042-8833-2018-10030
- Thaçi D, Augustin M, Westermayer B, Kamps A, Hennig M. Effectiveness of alitretinoin in severe chronic hand eczema: PASSION, a real-world observational study. J Dermatolog Treat. 2016;27:577.
- Blair HA, Scott LJ. Alitretinoin: A Review in Severe Chronic Hand Eczema. Drugs. 2016;76:1271. 10.1007/s40265-016-0621-0
- Politiek K, Christoffers WA, Coenraads PJ, Schuttelaar MA. Alitretinoin and acitretin in severe chronic hand eczema; results from a retrospective daily practice study. Dermatol Ther. 2016;29:364. 10.1111/dth.12362
- Urrutia S, Roustan G, Plazas MJ, Armengol S, Paz S, et al. Oral Alitretinoin in the Treatment of Severe Refractory Chronic Hand Eczema in the Spanish National Health System: Description and Analysis of Current Clinical Practice. Actas Dermosifiliogr. 2016;107:142. 10.1016/j.ad.2015.08.002
