Vitamin A protects against ulcers[Lose-dose treatment with vitamin A in prevention of stress ulcer in swine].
We focused on the protective effects of vitamin A on stress-induced gastric lesions in piglets after experiencing hemorrhagic shock. In our study, piglets were subjected to low blood pressure and then treated with different doses of vitamin A. Remarkably, those receiving vitamin A showed no signs of gastric lesions.
This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.
Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.
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Vitamin A prevents duodenal ulcersPrevention of duodenal ulcer formation in the rat by dietary vitamin A supplementation.
We explored the effects of dietary vitamin A on preventing duodenal ulcers in rats induced by cysteamine-HCl. In our study, we compared two groups of rats—one receiving a standard diet and the other supplemented with vitamin A.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
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Vitamin A and beta-carotene prevent ulcersInterrelationships between the gastric cytoprotective effects of vitamin A and beta-carotene and the gastric mucosal superoxide dismutase activity in rats.
In our investigation, we examined how vitamin A and beta-carotene impact gastric ulcers in rats. By administering these compounds before inducing gastric damage with ethanol or hydrochloric acid, we observed a notable reduction in both the number and severity of ulcers.
This suggests that both vitamin A and beta-carotene help protect the stomach lining. However, while they effectively prevent ulcers, they don't fully restore the activity of a crucial enzyme involved in gastric defense. Overall, we found that these vitamins play a key protective role, primarily due to their ability to act as antioxidants.
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Vitamin A assists ulcer healingLip ulceration associated with intravenous administration of zoledronic acid: report of a case.
We examined a unique case of lip ulcers linked to the intravenous use of zoledronic acid (ZA) in a patient undergoing treatment for metastatic breast cancer. Despite managing the patient's anemia and an E. coli infection, the ulcers persisted until ZA was discontinued.
After halting the medication, the ulcers healed within three months with a treatment plan that included systemic antibiotics and vitamins A and E. However, upon resuming ZA, recurrence occurred, but follow-up treatment kept the patient clear of lesions for 18 months.
This case highlights how vitamin A can aid in the healing of severe oral mucosal ulcers related to bisphosphonate therapy.
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Vitamin A protects against ARA-C damageProtective effect of vitamin A on ARA-C induced intestinal damage in mice.
We investigated whether vitamin A could shield against intestinal damage caused by ARA-C, a common leukemia treatment known for its side effects like mucosal lesions. Mice in our study were divided into several groups, some receiving vitamin A alongside ARA-C.
Our results revealed that mice treated with vitamin A showed significantly improved gut health compared to those who did not receive it. They exhibited better mucosal integrity and less tissue damage, suggesting that vitamin A can indeed play a protective role against the harmful effects of ARA-C.
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