Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
50 mg
250%

Top Medical Research Studies

9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

Most Useful Reviews

9
Effective for osteoporosis
2 people found this helpful
I was initially concerned about the capacity, but this was the old 2000 IU. I experienced sudden osteoporosis 15 years ago. At that time, I found it was recommended to consume 200 IU D3 daily. I hurriedly purchased D3 and began taking it. Three months later, my doctor remarked, “I don't know what you did, but keep it up.” Even then, doctors agreed bones don’t regenerate once they deteriorate. Since then, I’ve been consistent with D3. It’s essential to take it.
Read More
9
Strengthens bones
1 people found this helpful
I have taken this for a few years; it's very good. My D3 levels improved according to my blood test results. It's affordable compared to other brands and user-friendly at 2000 IU, which is easy to absorb. It strengthens bones and is high quality with good ingredients that can boost immunity, saving time in getting D3 from sunlight.
Read More
9
Strengthens teeth
Vitamin D3 comes in a container with 240 capsules, each containing 2,000 IU. It replenishes sunlight deficiency and strengthens bones and teeth. The capsules have no distinct taste. Take them with liquid calcium to aid absorption; the effect is excellent, and only one capsule is needed.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
  • All Researches
9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective for osteoporosis
2 people found this helpful
I was initially concerned about the capacity, but this was the old 2000 IU. I experienced sudden osteoporosis 15 years ago. At that time, I found it was recommended to consume 200 IU D3 daily. I hurriedly purchased D3 and began taking it. Three months later, my doctor remarked, “I don't know what you did, but keep it up.” Even then, doctors agreed bones don’t regenerate once they deteriorate. Since then, I’ve been consistent with D3. It’s essential to take it.
Read More
9
Strengthens bones
1 people found this helpful
I have taken this for a few years; it's very good. My D3 levels improved according to my blood test results. It's affordable compared to other brands and user-friendly at 2000 IU, which is easy to absorb. It strengthens bones and is high quality with good ingredients that can boost immunity, saving time in getting D3 from sunlight.
Read More
9
Strengthens teeth
Vitamin D3 comes in a container with 240 capsules, each containing 2,000 IU. It replenishes sunlight deficiency and strengthens bones and teeth. The capsules have no distinct taste. Take them with liquid calcium to aid absorption; the effect is excellent, and only one capsule is needed.
Read More
6
Less bone pain
3 people found this helpful
I purchased these supplements as they were good value and quality. They have significantly improved my vitamin D levels, resulting in a lot less bone pain and no more achy legs.
Read More
7.5
Enhances immune system
Vitamin D3 promotes calcium absorption, crucial for strong bones and teeth, and also strengthens the immune system. The dosage should ideally be agreed upon with a doctor or followed as indicated on the package. It helps address vitamin D deficiency, which our bodies cannot produce without sunlight. I ordered this jar for the first time and appreciated its quality. The capsules are small and easy to swallow.
Read More

Frequently Asked Questions

9
Effective for osteoporosis
2 people found this helpful
I was initially concerned about the capacity, but this was the old 2000 IU. I experienced sudden osteoporosis 15 years ago. At that time, I found it was recommended to consume 200 IU D3 daily. I hurriedly purchased D3 and began taking it. Three months later, my doctor remarked, “I don't know what you did, but keep it up.” Even then, doctors agreed bones don’t regenerate once they deteriorate. Since then, I’ve been consistent with D3. It’s essential to take it.
9
Strengthens bones
1 people found this helpful
I have taken this for a few years; it's very good. My D3 levels improved according to my blood test results. It's affordable compared to other brands and user-friendly at 2000 IU, which is easy to absorb. It strengthens bones and is high quality with good ingredients that can boost immunity, saving time in getting D3 from sunlight.
7.5
Enhances immune system
Vitamin D3 promotes calcium absorption, crucial for strong bones and teeth, and also strengthens the immune system. The dosage should ideally be agreed upon with a doctor or followed as indicated on the package. It helps address vitamin D deficiency, which our bodies cannot produce without sunlight. I ordered this jar for the first time and appreciated its quality. The capsules are small and easy to swallow.
9
Strengthens teeth
Vitamin D3 comes in a container with 240 capsules, each containing 2,000 IU. It replenishes sunlight deficiency and strengthens bones and teeth. The capsules have no distinct taste. Take them with liquid calcium to aid absorption; the effect is excellent, and only one capsule is needed.
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.

References

  1. Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
  2. Rajani AM, Mittal A, Kulkarni VU, Rajani KA, Rajani KA. Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty. Malays Orthop J. 2024;18:7. 10.5704/MOJ.2411.002
  3. Han K, Wang X. Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study. Medicine (Baltimore). 2024;103:e40171. 10.1097/MD.0000000000040171
image