Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.1
USERS' SCORE
Good
Based on 2 Reviews
8.5

Top Medical Research Studies

8
Vitamin C may support bone health
We explored the connection between vitamin C levels and bone mineral density (BMD) in individuals with diabetes. By examining a group of 74 diabetic patients alongside 26 age-matched non-diabetic controls, we focused on how vitamin C intake could potentially influence bone health. Our goal was to see if higher vitamin C levels were associated with improved BMD and whether this effect might be related to decreases in certain inflammatory markers like VCAM-1 and adiponectin.

The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.

Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
Read More
8
Vitamin C may reduce osteoporosis risk
We analyzed the impact of vitamin C on osteoporosis using data from a significant national health survey involving 1,536 participants. Our main goal was to understand how vitamin C, along with vitamins A and D, correlates with the risk of developing osteoporosis.

From our findings, we observed that increased intake of vitamin C was associated with a reduced likelihood of osteoporosis. Specifically, compared to those with low vitamin C intake, individuals with a higher intake had better odds of maintaining bone density. The results were particularly pronounced in women, individuals over 60, and those with higher body mass indexes (BMIs).

While our analysis emphasizes vitamin C's role, it's essential to note that it was studied alongside other vitamins, which may complicate understanding its isolated effect. Overall, the evidence suggests that including adequate amounts of vitamin C in our diets could be beneficial for bone health, particularly in vulnerable populations.
Read More
8
Vitamin C impacts osteoporosis treatment
We observed a fascinating case of a 15-year-old girl who faced some significant health issues, including spine fractures and persistent back pain. After being examined, she was diagnosed with scurvy, an uncommon nutritional deficiency, and osteoporosis.

This situation opened our eyes to the potential impact that Vitamin C might have on bone health. The girl, who was previously healthy, had displayed troubling symptoms for quite some time before we connected them to her diet. With her diagnosis came dietary modifications and supplementation with Vitamin C, aimed at tackling both the scurvy and the osteoporosis.

Over time, this approach led to a gradual recovery. The girl began to see improvements in her condition, highlighting the critical role of nutrition, specifically Vitamin C, in maintaining bone health, especially in young populations. This case serves as a reminder that even those considered low-risk can experience significant health challenges due to deficiencies.
Read More

Most Useful Reviews

9
Improved bone health
21 people found this helpful
I started taking this to complement my existing mineral regimen to help reverse osteoporosis. I have moved from the "high risk" to "normal risk" category for my age according to the dexascan, which is a significant improvement. While it seems to have alleviated neck and back issues, surprisingly, it also improved the rather sensitive issue of hemorrhoids. After childbirth, I had suffered with them daily, often with severe bleeding. For me to consider seeking professional help for a health issue is quite rare, highlighting how severe they were. Now, there is barely any puffiness, no pain, and no bleeding! I wholeheartedly recommend this product.
Read More
7.5
Aches significantly reduced
3 people found this helpful
Good for the price. The primary effect on my mother, the user, is that her aches have practically vanished. She has osteoporosis and arthritis, but with regular intake, these have significantly aided her in managing them.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.1
  • All Researches
8
Combination effects on osteoporosis
We explored the effects of hydrolyzed collagen (HC) and its combination with vitamin C on osteoporosis. The study highlighted that a daily intake of 12 grams of HC can help alleviate pain symptoms associated with osteoporosis and promote better bone health. However, it's important to note that the beneficial effects of vitamin C were discussed primarily in conjunction with HC, making it difficult to assess its standalone impact on osteoporosis treatment.

The research focused on how HC improves mineral density and protects joint cartilage, showcasing its potential therapeutic benefits. While we observed positive results in terms of overall health improvements, the clear effects of vitamin C alone were not explicitly detailed, which limits our understanding of its specific role in combating osteoporosis. Understanding the combined effects of these treatments can ultimately guide better therapeutic strategies for those at risk or suffering from osteoporosis.
Read More
8
Vitamin C may reduce osteoporosis risk
We analyzed the impact of vitamin C on osteoporosis using data from a significant national health survey involving 1,536 participants. Our main goal was to understand how vitamin C, along with vitamins A and D, correlates with the risk of developing osteoporosis.

From our findings, we observed that increased intake of vitamin C was associated with a reduced likelihood of osteoporosis. Specifically, compared to those with low vitamin C intake, individuals with a higher intake had better odds of maintaining bone density. The results were particularly pronounced in women, individuals over 60, and those with higher body mass indexes (BMIs).

While our analysis emphasizes vitamin C's role, it's essential to note that it was studied alongside other vitamins, which may complicate understanding its isolated effect. Overall, the evidence suggests that including adequate amounts of vitamin C in our diets could be beneficial for bone health, particularly in vulnerable populations.
Read More
We aimed to understand how vitamin C, particularly in the form of magnesium ascorbyl phosphate (MAP), could influence bone health and potentially combat conditions like osteoporosis. In our exploration, we focused on how MAP might enhance the growth and activity of bone-forming cells called osteoblasts.

Through our experiments, we found that MAP significantly encouraged the proliferation and differentiation of human skeletal stem and progenitor cells (SSPCs) in the lab. In live models, we observed that giving MAP by mouth helped reduce bone loss and improved the healing of bone defects by enhancing new bone formation.

On a deeper level, we uncovered that MAP interacts with a specific enzyme known as CaMKIIα, which plays a pivotal role in the signaling pathways that regulate bone health. This activation leads to further responses involving other important proteins that contribute to bone growth.

Overall, our results suggest that MAP could represent a promising new approach to treating bone loss disorders such as osteoporosis by fostering increased bone formation. With further research, MAP may pave the way for innovative treatment strategies in the field of bone health.
Read More
8
Vitamin C impacts osteoporosis treatment
We observed a fascinating case of a 15-year-old girl who faced some significant health issues, including spine fractures and persistent back pain. After being examined, she was diagnosed with scurvy, an uncommon nutritional deficiency, and osteoporosis.

This situation opened our eyes to the potential impact that Vitamin C might have on bone health. The girl, who was previously healthy, had displayed troubling symptoms for quite some time before we connected them to her diet. With her diagnosis came dietary modifications and supplementation with Vitamin C, aimed at tackling both the scurvy and the osteoporosis.

Over time, this approach led to a gradual recovery. The girl began to see improvements in her condition, highlighting the critical role of nutrition, specifically Vitamin C, in maintaining bone health, especially in young populations. This case serves as a reminder that even those considered low-risk can experience significant health challenges due to deficiencies.
Read More
8
Vitamin C may support bone health
We explored the connection between vitamin C levels and bone mineral density (BMD) in individuals with diabetes. By examining a group of 74 diabetic patients alongside 26 age-matched non-diabetic controls, we focused on how vitamin C intake could potentially influence bone health. Our goal was to see if higher vitamin C levels were associated with improved BMD and whether this effect might be related to decreases in certain inflammatory markers like VCAM-1 and adiponectin.

The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.

Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved bone health
21 people found this helpful
I started taking this to complement my existing mineral regimen to help reverse osteoporosis. I have moved from the "high risk" to "normal risk" category for my age according to the dexascan, which is a significant improvement. While it seems to have alleviated neck and back issues, surprisingly, it also improved the rather sensitive issue of hemorrhoids. After childbirth, I had suffered with them daily, often with severe bleeding. For me to consider seeking professional help for a health issue is quite rare, highlighting how severe they were. Now, there is barely any puffiness, no pain, and no bleeding! I wholeheartedly recommend this product.
Read More
7.5
Aches significantly reduced
3 people found this helpful
Good for the price. The primary effect on my mother, the user, is that her aches have practically vanished. She has osteoporosis and arthritis, but with regular intake, these have significantly aided her in managing them.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Al Hajj W, Salla M, Krayem M, Khaled S, Hassan HF, et al. Hydrolyzed collagen: Exploring its applications in the food and beverage industries and assessing its impact on human health - A comprehensive review. Heliyon. 2024;10:e36433. doi:10.1016/j.heliyon.2024.e36433
  2. Wang Q, Yu H, Kong Y. Association of vitamins with bone mineral density and osteoporosis measured by dual-energy x-ray absorptiometry: a cross-sectional study. BMC Musculoskelet Disord. 2024;25:69. doi:10.1186/s12891-024-07173-y
  3. Chen Y, Wei Z, Shi H, Wen X, Wang Y, et al. BushenHuoxue formula promotes osteogenic differentiation via affecting Hedgehog signaling pathway in bone marrow stem cells to improve osteoporosis symptoms. PLoS One. 2023;18:e0289912. doi:10.1371/journal.pone.0289912
  4. Zhou Q, Chen X, Chen Q, Hao L. Independent and combined associations of dietary antioxidant intake with bone mineral density and risk of osteoporosis among elderly population in United States. J Orthop Sci. 2024;29:1064. doi:10.1016/j.jos.2023.07.014
  5. Xie Y, Bao Z, Wang Z, Du D, Chen G, et al. Magnesium Ascorbyl Phosphate Promotes Bone Formation Via CaMKII Signaling. J Bone Miner Res. 2023;38:1015. doi:10.1002/jbmr.4820
  6. Ku Md Saad S, Khalid K, Glackin S. Fatigue, bleeding tendency and osteoporosis in an adolescent: a diagnostic conundrum. Oxf Med Case Reports. 2023;2023:omad015. doi:10.1093/omcr/omad015
  7. Jain SK, McLean WE, Stevens CM, Dhawan R. The Positive Association of Plasma Levels of Vitamin C and Inverse Association of VCAM-1 and Total Adiponectin with Bone Mineral Density in Subjects with Diabetes. Nutrients. 2022;14. doi:10.3390/nu14193893
  8. Mangano KM, Noel SE, Dawson-Hughes B, Tucker KL. Sufficient Plasma Vitamin C Is Related to Greater Bone Mineral Density among Postmenopausal Women from the Boston Puerto Rican Health Study. J Nutr. 2021;151:3764. doi:10.1093/jn/nxab291
  9. Marom R, Burrage LC, Venditti R, Clément A, Blanco-Sánchez B, et al. COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. Am J Hum Genet. 2021;108:1710. doi:10.1016/j.ajhg.2021.08.002
  10. Moazen M, Mazloom Z, Tanideh N, Dabbaghmanesh MH, Rahmdel S, et al. Osteoprotective effects of kefir fortified with omega-3 and vitamin C in ovariectomized rats. Int J Vitam Nutr Res. 2023;93:200. doi:10.1024/0300-9831/a000718
  11. Rondanelli M, Peroni G, Fossari F, Vecchio V, Faliva MA, et al. Evidence of a Positive Link between Consumption and Supplementation of Ascorbic Acid and Bone Mineral Density. Nutrients. 2021;13. doi:10.3390/nu13031012
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