Medical Researches
Possibly Effective
Based on 16 Researches
Probiotic effectively reduces diarrheaEffectiveness of Saccharomyces boulardii CNCM I-745 in Adult Indian Patients with Diarrhoea: A Real-world, Multicentre, Retrospective, Comparative Study.
Highly relevant real-world evidence
We investigated the effectiveness of the probiotic Saccharomyces boulardii CNCM I-745 in real-world settings for treating diarrhea. In a study involving over 30,000 patients, those treated with S. boulardii had a notable success rate of 77.8% in resolving their diarrhea, compared to just 15.8% in the control group.
This study showed that S. boulardii worked well even when patients were on antibiotics, outperforming traditional anti-diarrheal treatments.
Overall, S. boulardii demonstrates significant promise in managing diarrhea effectively.
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Probiotic reduces antibiotic-associated diarrheaHigh-dose Probiotic Mix of spp., spp., , and to Prevent Antibiotic-associated Diarrhea in Adults: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial (SPAADA).
Study finds significant health benefits
We examined how a high-dose, multistrain probiotic mix called Sinquanon helps prevent antibiotic-associated diarrhea (AAD) in adults taking broad-spectrum antibiotics. This well-structured clinical trial involved 564 participants, half receiving the probiotic and half a placebo.
Results showed that fewer people in the probiotic group experienced AAD—only 9.2% compared to 25.3% in the placebo group. This promising improvement suggests that Sinquanon may significantly enhance gastrointestinal health during antibiotic treatment without causing harmful side effects.
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Probiotics mitigate antibiotic-related diarrheaCan the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?
High relevance to gut health
We looked into how probiotics, especially Saccharomyces boulardii CNCM I-745, can impact antibiotic-associated diarrhea. Through systematic reviews and clinical trials, we found that this yeast is effective in preventing and resolving diarrhea linked to antibiotic use. Since it isn't affected by antibiotics, S. boulardii can safely be administered at the start of treatment or within the first couple of days. This shows that using the right probiotics can help restore gut health after antibiotics, which is crucial for overall well-being.
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Probiotics show potential for AADOverview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children.
Moderate evidence, further research needed
We looked into how probiotics might help manage antibiotic-associated diarrhea (AAD) in children through a review of systematic reviews. Our review considered various databases and included 20 studies, evaluating their reporting quality and overall evidence strength. While we found that higher doses of probiotics show promise in preventing AAD, caution is needed as many studies had significant quality gaps. Overall, probiotics could benefit kids facing AAD, but more robust research is essential for clearer recommendations.
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We explored the effects of Saccharomyces boulardii on diarrhea caused by the cancer drug abemaciclib in a study involving thirty rats. The rats were divided into three groups: a control group, a group receiving only abemaciclib, and a group receiving both abemaciclib and Saccharomyces boulardii.
Our results indicated that the group treated with Saccharomyces boulardii showed a significant reduction in diarrhea severity and weight loss compared to the group that only received abemaciclib. Furthermore, histopathological evaluations revealed less inflammation in the Saccharomyces boulardii group. Overall, this suggests that Saccharomyces boulardii might be a beneficial treatment option to alleviate chemotherapy-induced diarrhea.
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User Reviews
I like the addition of Cardamom and Saccharomyces boulardii. This probiotic’s blend includes ingredients known to assist with diarrhea and overall gut health. As a family member dealing with Ulcerative Colitis is introducing this, I find it beneficial without adverse effects. We will continue ordering, as it has proven helpful.
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Quick relief after antibiotics
Really helped after taking large doses of antibiotics. Post-diverticulitis, I experienced bloating and diarrhea. After consultation, my doctor recommended this probiotic, which greatly improved my gut health within 24 hours. I highly recommend it if you’ve taken antibiotics.
Five Stars if You Have Chronic Loose Stools. New Chapter makes excellent supplements, and I’ve used many for long periods with great results. This probiotic is effective in addressing chronic diarrhea. Though I have lupus which complicates my gut health, for others who struggle with loose stools, this is the probiotic to try.
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