Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride from ferment media)
1.2 mg
100%
Riboflavin (from ferment media)
1.3 ng
100%
Niacin (as niacinamide from ferment media)
16 mg
100%
Vitamin B6 (as pyridoxine hydrochloride from ferment media)
3.4 mg
200%
Folate (as L-5-methylfolate)
400 mcg DFE
100%
Vitamin B12 (7.2 mcg as cyanocobalamin from ferment media and 4.8 mcg  methylcobalamin)
12 mcg
500%
Biotin (from ferment media)
30 mcg
100%
Pantothenic Acid (as calcium D-pantothenate from ferment media)
5 mg
100%
Energy and Digestion Support Blend Organic Maca (root), Organic Schizandra (fruit), Organic Cardamom (seed)
75 mg
*

Top Medical Research Studies

We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.

After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.

Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
Nicotinamide suppresses autoimmune activation
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.

Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More

Most Useful Reviews

9
Highly effective treatment
Worth the price! It’s truly effective with no adverse side effects. I highly recommend it and will order again!
Read More
7.5
Immediate improvement noted
The product was well-arranged and perfectly packaged, and I can definitely feel its effects. I will certainly order more as it was also delivered swiftly.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
  • All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.

After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.

Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Nicotinamide suppresses autoimmune activation
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.

Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.

Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Highly effective treatment
Worth the price! It’s truly effective with no adverse side effects. I highly recommend it and will order again!
Read More
7.5
Immediate improvement noted
The product was well-arranged and perfectly packaged, and I can definitely feel its effects. I will certainly order more as it was also delivered swiftly.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. 10.59556/japi.73.0892
  2. Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. 10.1186/s13256-025-05149-7
  3. Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. 10.1186/s13256-025-05095-4
  4. Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. 10.3390/nu16162665
  5. Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. 10.1136/bcr-2023-258703
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