Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride from ferment media)
1.2 mg
100%
Riboflavin (from ferment media)
1.3 ng
100%
Niacin (as niacinamide from ferment media)
16 mg
100%
Vitamin B6 (as pyridoxine hydrochloride from ferment media)
3.4 mg
200%
Folate (as L-5-methylfolate)
400 mcg DFE
100%
Vitamin B12 (7.2 mcg as cyanocobalamin from ferment media and 4.8 mcg  methylcobalamin)
12 mcg
500%
Biotin (from ferment media)
30 mcg
100%
Pantothenic Acid (as calcium D-pantothenate from ferment media)
5 mg
100%
Energy and Digestion Support Blend Organic Maca (root), Organic Schizandra (fruit), Organic Cardamom (seed)
75 mg
*

Top Medical Research Studies

9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More

Most Useful Reviews

9
No nausea
4 people found this helpful
Perfectly, this complex is very good and easily digestible. I experienced no nausea and had no negative response from my kidneys. If you found my review helpful, please reply with "YES". Thank you.
Read More
9
No GI upset
1 people found this helpful
Only Vitamin B formulation that doesn't make me feel nauseated. Although graphic, it’s true. I’ve had multivitamins I had to take with food, which still upset my stomach. This New Chapter Vitamin B complex is made from whole food, making it healthier. I have never encountered nausea or any GI upset in four years of taking them, even trying their multivitamin. High-quality products, worth the cost.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
  • All Researches
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No nausea
4 people found this helpful
Perfectly, this complex is very good and easily digestible. I experienced no nausea and had no negative response from my kidneys. If you found my review helpful, please reply with "YES". Thank you.
Read More
9
No GI upset
1 people found this helpful
Only Vitamin B formulation that doesn't make me feel nauseated. Although graphic, it’s true. I’ve had multivitamins I had to take with food, which still upset my stomach. This New Chapter Vitamin B complex is made from whole food, making it healthier. I have never encountered nausea or any GI upset in four years of taking them, even trying their multivitamin. High-quality products, worth the cost.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. doi:10.1097/ALN.0000000000005354
  2. Hayashi E, Matuura T, Takano J, Morofushi K, Toriizuka K, et al. Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi. Palliat Support Care. 2024;22:1511. doi:10.1017/S1478951524000415
  3. Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. doi:10.1007/s40268-023-00425-7
  4. Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. doi:10.1007/s00404-023-06925-w
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