We investigated how exposure to ultrafine particles (UFPs) in cold and humid environments impacts respiratory health. Using a controlled study with male Balb/c mice, we found that exposure to carbon black nanoparticles worsened lung function and increased inflammation and oxidative stress.
Notably, the combination of UFPs and cold-humid conditions intensified these adverse effects. However, when we administered Vitamin E, it helped reduce these harmful impacts. This suggests that Vitamin E could be a potential protector against indoor air pollutants, offering insights for healthier living spaces.
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Most Useful Reviews
9
Better circulation noted
5 people found this helpful
I've been on megavitamins for several years due to concerning health check results. I take 2000 IU daily; they're small and easy to take, and significantly improve my sensitivity to cold! My blood circulation has enhanced, leading to improved health check results. I plan to continue this for life.
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9
Warm hands and feet
3 people found this helpful
I switched to this vitamin E three months ago. My cold sensitivity was so extreme that even in summer, my hands and feet felt cold. However, this summer, my feet are warm even when barefoot, which surprises my family. Additionally, I used to rely on painkillers for period discomfort, but since taking this, I've had no need for them. Switching was indeed the right decision.
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7.5
Symptoms improvement noted
2 people found this helpful
With worsening Raynaud's symptoms turning my fingers white in the cold, I started taking Vitamin E following the Fujikawa Method. After about a month of 2-3 tablets daily, the whitening reduced significantly. My symptoms, which intensified over 10 years, are now improving remarkably. Though I take other supplements, the quick positive change is surprising. My menstrual cycle has also stabilised, enhancing my overall quality of life.
We investigated how exposure to ultrafine particles (UFPs) in cold and humid environments impacts respiratory health. Using a controlled study with male Balb/c mice, we found that exposure to carbon black nanoparticles worsened lung function and increased inflammation and oxidative stress.
Notably, the combination of UFPs and cold-humid conditions intensified these adverse effects. However, when we administered Vitamin E, it helped reduce these harmful impacts. This suggests that Vitamin E could be a potential protector against indoor air pollutants, offering insights for healthier living spaces.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 30 Reviews
7.2
All Reviews
Positive Reviews
Negative Reviews
9
Better circulation noted
5 people found this helpful
I've been on megavitamins for several years due to concerning health check results. I take 2000 IU daily; they're small and easy to take, and significantly improve my sensitivity to cold! My blood circulation has enhanced, leading to improved health check results. I plan to continue this for life.
Read More
9
Warm hands and feet
3 people found this helpful
I switched to this vitamin E three months ago. My cold sensitivity was so extreme that even in summer, my hands and feet felt cold. However, this summer, my feet are warm even when barefoot, which surprises my family. Additionally, I used to rely on painkillers for period discomfort, but since taking this, I've had no need for them. Switching was indeed the right decision.
Read More
7.5
Symptoms improvement noted
2 people found this helpful
With worsening Raynaud's symptoms turning my fingers white in the cold, I started taking Vitamin E following the Fujikawa Method. After about a month of 2-3 tablets daily, the whitening reduced significantly. My symptoms, which intensified over 10 years, are now improving remarkably. Though I take other supplements, the quick positive change is surprising. My menstrual cycle has also stabilised, enhancing my overall quality of life.
Read More
9
Reduced sensitivity to cold
I take it for PMS relief. Adjusting the amount made it effective for improved blood flow. My sensitivity to cold has noticeably decreased, so I want to continue using it. I find it essential to drink it with mineral supplements each morning for better results. Now, I can sleep without socks even in winter, and during summer, I can wear short sleeves in air-conditioned rooms, which is delightful!
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7.5
Improved blood flow
I take this to alleviate menstrual and ovulation pain. After switching to mixed tocopherols, my feet, which were abnormally cold in winter, feel warmer now, and my menstrual pain has lessened significantly. This is one supplement I plan to keep using.
Cold is a term that refers to a state of low temperature, often associated with a perceptibly chilly environment or the sensation of being cool to the touch. Scientifically, cold is relative to the presence and movement of heat, which is a measure of energy within matter. In everyday terms, we experience cold through weather changes, such as during winter months, and it can also be described in the context of specific temperature ranges – for example, temperatures below 32 degrees Fahrenheit (0 degrees Celsius) generally signify freezing conditions, which can impact outdoor activities, personal comfort, and various ecological systems.
Moreover, the sensation of cold is not solely dependent on temperature; factors like humidity and wind chill can enhance the feeling of coldness. When discussing cold in terms of human health, prolonged exposure to cold conditions can lead to hypothermia or frostbite if body heat is not effectively maintained. Hence, it's crucial to dress appropriately and take necessary precautions during colder months to prevent adverse effects. Understanding the concept of cold can help individuals better prepare for seasonal changes and ensure their comfort and safety.
Vitamin E is a fat-soluble nutrient that plays a crucial role in various bodily functions, primarily acting as an antioxidant. This means it helps to neutralize free radicals, which are unstable molecules that can cause oxidative stress, leading to cellular damage. Vitamin E is not just one compound, but a group of several related compounds, with tocopherols and tocotrienols being the most studied forms. These compounds are found in various foods, including nuts, seeds, and green leafy vegetables, making it relatively easy to obtain sufficient amounts through a balanced diet.
Research suggests that Vitamin E may contribute to immune function, skin health, and the overall maintenance of cardiovascular health. While most people can get enough Vitamin E from their diet, supplements may be necessary for those with specific deficiencies or conditions that impair absorption. However, it’s important to consult a healthcare provider before starting any supplement regimen, as excessive intake of Vitamin E can lead to adverse effects. Overall, maintaining adequate Vitamin E levels is essential for promoting long-term health and preventing potential deficiencies.
Based on user reviews, the time it takes to see results from this supplement for cold sensitivity varies, but several users report noticeable improvements within a matter of days to months. For instance, one user mentioned feeling their cold feet return to normal after just three days of taking the supplement daily Read Review. Another reported significant changes after approximately a month, stating that their symptoms of cold sensitivity, previously worsening over a decade, improved remarkably Read Review.
Additionally, users have noted that their overall quality of life improved alongside the reduction in cold sensitivity, with several continuing to take the supplement long-term for sustained benefits. Overall, users' experiences suggest that while some may see rapid results within days, others may require consistent use over several weeks to a month to fully experience the benefits Read Review.
The research suggests that Vitamin E may provide protective effects against respiratory issues exacerbated by cold and humid conditions, particularly concerning ultrafine particles (UFPs). In a controlled study involving male Balb/c mice, exposure to UFPs resulted in worsened lung function and heightened inflammation when combined with cold-humid environments. Interestingly, the administration of Vitamin E appeared to mitigate these harmful effects, indicating its potential as a beneficial supplement for those exposed to such conditions [1].
While this study offers promising insights into Vitamin E's protective role in respiratory health amidst cold environments, more research is necessary to fully validate its efficacy and applicability in human populations. Currently, the evidence supports the idea that Vitamin E may aid in reducing respiratory health risks linked to cold, humid conditions, but further studies could enhance our understanding and ability to recommend this supplement for general use against cold-related health issues.
Based on user reviews, many individuals report significant improvements in their sensitivity to cold after using vitamin E supplements. For example, users have noted that they no longer feel the extreme cold in their hands and feet, even during winter months, and some have experienced enhanced blood circulation as a result Read ReviewRead Review, Read Review. One reviewer mentioned feeling their feet warm up significantly after three days of supplementation Read Review. Additionally, users have praised the supplement for its role in alleviating menstrual pain, which they attribute to a combination of improved blood flow and reduced cold sensitivity Read Review.
Anecdotal experiences indicate that some users have found relief from cold extremities, which in turn has increased their overall comfort during colder months Read Review. Notably, improvements are not solely limited to cold sensitivity; several reviewers also report enhanced skin hydration and a more radiant complexion, suggesting a broader array of benefits that may come with consistent use Read Review. While outcomes can vary from person to person, these user accounts reflect positive changes attributed to vitamin E supplementation.
Based on user reviews, many individuals have successfully combined vitamin E with other supplements to manage cold sensitivity and related health issues. For instance, one user noted that taking vitamin E alongside B vitamins enhanced their overall effectiveness, reporting fewer instances of catching colds and improved circulation that allowed them to go without socks during winter Read Review. Another user mentioned using vitamin C in conjunction with their vitamin E regimen to support its benefits, which reportedly helped their cold feet warm up significantly within just a few days Read Review.
Moreover, several users have indicated that combining vitamin E with other elements like iron and protein—following the Fujikawa Method—has dramatically improved their long-standing cold sensitivity Read Review. One reviewer who followed this method expressed surprise at the extent of their improvement over the year, attributing vitamin E as a crucial factor in their enhanced comfort during colder months Read Review. Overall, these user accounts suggest that combining vitamin E with other dietary supplements may amplify its effects, leading to greater comfort and health during cold seasons.
Based on user reviews, the appropriate dosage of Vitamin E for mitigating cold sensitivity varies among individuals but seems to hover around 2000 IU daily for many. One user reports taking 2000 IU daily and has experienced significant improvements in cold sensitivity and blood circulation (Read Review). Another user mentioned taking 2–4 tablets daily to combat cold extremities effectively (Read Review). Reports also suggest that dosing may be tailored depending on personal comfort and symptom severity; for instance, one user adjusts their intake during winter months for better results (Read Review).
Users emphasize the importance of monitoring their total intake due to Vitamin E’s fat-soluble nature. Some suggest sticking to lower doses, like one tablet every four days, to avoid excess, while others feel confident with daily multiple doses for lasting benefit (Read Review). Overall, it appears that while many find success with higher doses, flexibility in dosage is key to accommodate individual health needs and responses.Read Review
7.5
Warmer feet now
4 people found this helpful
I was told it’s beneficial for frostbite and menopause. Taking it with vitamin C after meals is recommended. After just three days, my feet no longer feel cold. I take two tablets daily—morning and night—though I plan to reduce that to one eventually. The fishy smell isn't off-putting, and the tablets are easy to swallow.
7.5
Symptoms improvement noted
2 people found this helpful
With worsening Raynaud's symptoms turning my fingers white in the cold, I started taking Vitamin E following the Fujikawa Method. After about a month of 2-3 tablets daily, the whitening reduced significantly. My symptoms, which intensified over 10 years, are now improving remarkably. Though I take other supplements, the quick positive change is surprising. My menstrual cycle has also stabilised, enhancing my overall quality of life.
9
Effective daily use
3 people found this helpful
Ideal for those prone to feeling cold, I’ve noticed a marked improvement in my blood circulation and a warming of my cold feet since I started taking this supplement daily. I find it quite effective.
9
Better circulation noted
5 people found this helpful
I've been on megavitamins for several years due to concerning health check results. I take 2000 IU daily; they're small and easy to take, and significantly improve my sensitivity to cold! My blood circulation has enhanced, leading to improved health check results. I plan to continue this for life.
0
Skin condition improved
5 people found this helpful
This product alleviates my cold extremities, particularly in my hands and feet. I've observed my skin's moisture and shine improving. However, as it's a fat-soluble vitamin, I take care not to exceed the recommended dosage. Previously, I took a mega dose of vitamin D and felt unwell after three months, prompting me to stop—and my health improved soon after.
7.5
Alleviated coldness
I bought this because of my low body temperature due to menopause. It has alleviated the coldness in my feet, and I feel it effectively helps to raise my body temperature.
7.5
Dramatic pain relief
1 people found this helpful
I've suffered from menstrual cramps for many years and tried various supplements without much effect. After taking Vitamin E twice a day, my period pain has decreased dramatically. Initially, I thought this relief might be temporary, but in the second month, I experienced almost no pain. The coldness has also diminished, and overall, blood flow seems to have improved. This is truly a significant decision for me.
6
Less cold frequency
1 people found this helpful
My skin has become more hydrated and glowing, with my hair and nails improving too. Vitamin E has effectively addressed my dry skin, firming it up. After several weeks of use, I noticed stronger, shinier hair. Additionally, my immunity seems strengthened, and I catch colds less often. Vitamin E has also enhanced my vision and reduced eye fatigue from long hours at the computer.
7.5
Prevent cold effectively
1 people found this helpful
I feel like I don't catch a cold when I take this. Alongside this, I also consume B vitamins each morning. I've been repeating this so consistently that I worry if I miss a dose.
7.5
Improvements noted
2 people found this helpful
I follow the Fujikawa theory, which involves iron, protein, vitamin E, vitamin C, and B vitamins, plus niacin. Despite protein not suiting my stomach, I've switched to a high-protein diet. Over a year, my long-standing sensitivity to cold has considerably improved—I'm surprised, as I had given up hope. I believe vitamin E plays a crucial role, and I'm curious about further improvements.
7.5
Relieved chilblains effectively
1 people found this helpful
Indispensable in cold weather, once the temperature drops from autumn to spring, my blood circulation declines, leading to chilblains. However, taking 2 to 4 tablets daily has made a significant difference. I am cautious about excessive Vitamin E intake as it may affect Vitamin K, so I ensure to include natto at breakfast for balance.
7
Cold sensitivity aid
I’ve made several purchases. To significantly improve my sensitivity to cold, I take more during winter. I'd say my cold sensation has improved.
6
Catches colds less
14 people found this helpful
I advise against catching a cold. I bought Vitamin E believing it would help me avoid one. Usually, I fall ill with seasonal changes, but this year I fared much better. Since vitamin E is fat-soluble, I must watch for overdose, so I only take one tablet every four days.
8
Vitamin E mitigates respiratory damage
A molecular toxicological study to explore potential health risks associated with ultrafine particle exposure in cold and humid indoor environments.
We investigated how exposure to ultrafine particles (UFPs) in cold and humid environments impacts respiratory health. Using a controlled study with male Balb/c mice, we found that exposure to carbon black nanoparticles worsened lung function and increased inflammation and oxidative stress.
Notably, the combination of UFPs and cold-humid conditions intensified these adverse effects. However, when we administered Vitamin E, it helped reduce these harmful impacts. This suggests that Vitamin E could be a potential protector against indoor air pollutants, offering insights for healthier living spaces.
References
Shu Z, Qing S, Yang X, Ma P, Wu Y, et al. A molecular toxicological study to explore potential health risks associated with ultrafine particle exposure in cold and humid indoor environments. Ecotoxicol Environ Saf. 2025;289:117638. doi:10.1016/j.ecoenv.2024.117638