Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopherol)
268 mg
1787%
Top Medical Research Studies
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
Read More
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
Read More
Most Useful Reviews
9
Headache reduction
It has improved my blood circulation and reduced headaches. I want to continue as it's recommended.
Read More
7.5
Reduced headaches significantly
8 people found this helpful
I take two tablets each morning, avoiding them with iron at night. Since I began, my unexplained headaches have eased considerably. This supplement also has antioxidant properties, which I appreciate.
Read More
7.5
Beauty enhancement
I take it for beauty and to improve headaches. The soft gel is easy to swallow, and as it's natural vitamin E, I can take it with peace of mind.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
- All Researches
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
8
Vitamin E shows potential for migraines
We conducted a randomized, double-blind, sham-controlled pilot study to explore the effects of a combined antioxidant treatment—N-acetylcysteine, vitamin E, and vitamin C—on headaches in adults suffering from migraines.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
Read More
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
Read More
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
Read More
7
We explored the effectiveness of a supplement combining pine bark extract and antioxidants, including vitamin E, for patients suffering from migraines that didn't respond to traditional medications.
In a small group of twelve participants, we saw potential improvements in headache frequency and severity after a three-month treatment period. Patients took capsules containing this antioxidant formulation while continuing their usual medications.
While the results are promising, further studies are required to fully assess the benefits of these antioxidants in migraine management.
In a small group of twelve participants, we saw potential improvements in headache frequency and severity after a three-month treatment period. Patients took capsules containing this antioxidant formulation while continuing their usual medications.
While the results are promising, further studies are required to fully assess the benefits of these antioxidants in migraine management.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Headache reduction
It has improved my blood circulation and reduced headaches. I want to continue as it's recommended.
Read More
7.5
Reduced headaches significantly
8 people found this helpful
I take two tablets each morning, avoiding them with iron at night. Since I began, my unexplained headaches have eased considerably. This supplement also has antioxidant properties, which I appreciate.
Read More
7.5
Beauty enhancement
I take it for beauty and to improve headaches. The soft gel is easy to swallow, and as it's natural vitamin E, I can take it with peace of mind.
Read More
7.5
Fewer headaches
I've been taking it for sensitivity to cold, headaches, and stiff shoulders. It does seem I have fewer bad days.
Read More
6
Limited pain relief
7 people found this helpful
Despite trying vitamin E for improved blood flow in my long-standing headaches, it hasn't competed with changes due to menstruation or weather. However, after two months, people mentioned my skin looked great, perhaps due to this supplement. I'd be pleased if it helps with my headaches.
Read More
Frequently Asked Questions
7.5
Reduced headaches significantly
8 people found this helpful
I take two tablets each morning, avoiding them with iron at night. Since I began, my unexplained headaches have eased considerably. This supplement also has antioxidant properties, which I appreciate.
7.5
Fewer headaches
I've been taking it for sensitivity to cold, headaches, and stiff shoulders. It does seem I have fewer bad days.
6
Limited pain relief
7 people found this helpful
Despite trying vitamin E for improved blood flow in my long-standing headaches, it hasn't competed with changes due to menstruation or weather. However, after two months, people mentioned my skin looked great, perhaps due to this supplement. I'd be pleased if it helps with my headaches.
2
Possible headache cause
I tried E-400 with mixed tocopherols and, although the quality is excellent, I began experiencing headaches, likely due to the high dosage. I advise others to assess their dosage before starting.
7.5
Helps with tension headaches
I've taken this supplement daily for years, contributing to my wellness. When I experience tension headaches, taking them helps reduce the pain effectively.
8
Vitamin E shows potential for migraines
We conducted a randomized, double-blind, sham-controlled pilot study to explore the effects of a combined antioxidant treatment—N-acetylcysteine, vitamin E, and vitamin C—on headaches in adults suffering from migraines.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
References
- Visser EJ, Drummond PD, Lee-Visser JLA. Reduction in Migraine and Headache Frequency and Intensity With Combined Antioxidant Prophylaxis (N-acetylcysteine, Vitamin E, and Vitamin C): A Randomized Sham-Controlled Pilot Study. Pain Pract. 2020;20:737. doi:10.1111/papr.12902
- Lauritsen CG, Chua AL, Nahas SJ. Current Treatment Options: Headache Related to Menopause-Diagnosis and Management. Curr Treat Options Neurol. 2018;20:7. doi:10.1007/s11940-018-0492-7
- Bütün A, Nazıroğlu M, Demirci S, Çelik Ö, Uğuz AC. Riboflavin and vitamin E increase brain calcium and antioxidants, and microsomal calcium-ATP-ase values in rat headache models induced by glyceryl trinitrate. J Membr Biol. 2015;248:205. doi:10.1007/s00232-014-9758-5
- Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med Sci Monit. 2009;15:CR16.
- Chayasirisobhon S. Use of a pine bark extract and antioxidant vitamin combination product as therapy for migraine in patients refractory to pharmacologic medication. Headache. 2006;46:788.
