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NOW Supplements Vitamin E
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopherol)
268 mg
1787%

Top Medical Research Studies

9
Vitamin E alleviates leg cramps
Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol).
High relevance due to findings
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.

Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.

Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E effective for leg cramps
Dialysis leg cramps. Efficacy of quinine versus vitamin E.
Relevant for dialysis treatment
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.

After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.

Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.

However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More
7
Vitamin E shows limited effectiveness
Are there alternatives to the use of quinine to treat nocturnal leg cramps?
Relevant for alternative therapies
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More

Most Useful Reviews

9.5
Menstrual cramps improved
You look fabulous! This supplement has significantly improved my menstrual cramps. I take 5 tablets each day.
Read More
9.5
Menstrual cramps easier
My menstrual cramps are becoming more manageable.
Read More
9.5
Much easier periods
I recommend this for anyone suffering from menstrual cramps. After starting on Vitamin E, my cramps have become much easier, nearly eliminating my pre-menstrual rough skin. It appears there are no side effects even with higher dosages, allowing for flexible amounts to try.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
  • All Researches
9
Vitamin E alleviates leg cramps
Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol).
High relevance due to findings
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.

Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.

Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E shows limited effectiveness
Are there alternatives to the use of quinine to treat nocturnal leg cramps?
Relevant for alternative therapies
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More
7
Vitamin E effective for leg cramps
Dialysis leg cramps. Efficacy of quinine versus vitamin E.
Relevant for dialysis treatment
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.

After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.

Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.

However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Menstrual cramps improved
You look fabulous! This supplement has significantly improved my menstrual cramps. I take 5 tablets each day.
9.5
Menstrual cramps easier
My menstrual cramps are becoming more manageable.
9.5
Much easier periods
I recommend this for anyone suffering from menstrual cramps. After starting on Vitamin E, my cramps have become much easier, nearly eliminating my pre-menstrual rough skin. It appears there are no side effects even with higher dosages, allowing for flexible amounts to try.
8.3
Effective for cramps
I took Vitamin E for leg cramps prior to knee surgery, and it worked well for me.
8.8
Improved menstrual cramps
I've been taking one tablet daily in the morning, and my wife has mentioned that her menstrual cramps have improved since starting Vitamin E as well.
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