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NOW Supplements Acidophilus
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*

The product is found useful for the following medical conditions

Diarrhea details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
USERS' SCORE
Good
Based on 14 Reviews
8.8
8
Probiotics may shorten diarrhea duration
Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan.
Most Relevant Research
We looked into how effective probiotics, specifically Lactobacillus acidophilus and others commonly available in Japan, are in treating diarrhea caused by acute gastroenteritis in children.

In our analysis of 14 studies, we found that children who took probiotics had diarrhea lasting about one day shorter and fewer were hospitalized compared to those receiving a placebo.

However, the overall evidence is considered very low, suggesting that while there might be some benefits, more research is needed.
10
Chronic diarrhea fixed
Most Useful Review
No more diarrhoea! After struggling with chronic diarrhoea for months, I decided to try a probiotic. I went from experiencing intestinal cramping and diarrhoea 6-8 times a day to no diarrhoea at all. After just three days, I had my first "normal poop"—a wonderful change! Highly recommend!

Yeast Infection details

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8
USERS' SCORE
Good
Based on 9 Reviews
8.8
9
L. acidophilus inhibits C. albicans
Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella.
Most Relevant Research
We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.

Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
10
Effective prevention method
Most Useful Review
Great for preventing yeast infections. I suffered from severe yeast infections almost monthly, particularly when on antibiotics. Three years ago, I started this probiotic and haven't had a yeast infection since, even while taking antibiotics. It's definitely worth trying for anyone dealing with chronic yeast infections!

Heartburn details

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.7
8
Positive effects on gastrointestinal symptoms
Effect of a symbiotic gel (Lactobacillus acidophilus + Bifidobacterium lactis + inulin) on presence and severity of gastrointestinal symptoms in hemodialysis patients.
Most Relevant Research
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.

We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.

Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
9.5
Cured my heartburn
Most Useful Review
The acidophilus bacillus resides in the stomach and is the only helpful bacteria able to thrive in such an acidic environment. It prevents Helicobacter pylori from settling there. Thanks to acidophilus sticks, my stomach is healthy, preventing heartburn. When the stomach is very acidic, the sphincter between the stomach and the oesophagus closes tightly, keeping the stomach's contents from entering the oesophagus, thus alleviating heartburn. This is how I overcame reflux esophagitis that troubled me for years.

Reflux details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 7 Reviews
8.7
8
Probiotics repair DNA in GERD
sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease.
Most Relevant Research
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.

Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
9.5
Eliminated heartburn
Most Useful Review
The acidophilus bacillus thrives in the stomach, being the only beneficial bacterium able to survive in such acidic conditions, preventing Helicobacter pylori from settling. Thanks to acidophilus, my stomach remains healthy and prevents heartburn, as a very acidic environment ensures that the sphincter closes tightly, stopping stomach contents from refluxing into the oesophagus. This is how I overcame reflux esophagitis that had troubled me for years.

Ear Infection details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Prevented yeast infections
Most Useful Review
This probiotic has been a game changer for me. I used to suffer from severe yeast infections almost monthly, often triggered by antibiotics. Since I started this probiotic three years ago, I haven't faced a yeast infection, even while on antibiotics. I highly recommend it for anyone dealing with chronic yeast infections!

Indigestion details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Synbiotic improves digestive health
Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults.
Most Relevant Research
This study looked into how a specific synbiotic product, which includes Lactobacillus acidophilus along with other probiotics and fructooligosaccharides, affects digestive health among healthy adults. In a randomized, double-blind, placebo-controlled design, we monitored 36 participants—20 women and 16 men aged between 25 and 45 years—over six weeks.

Participants received either the synbiotic supplement or a placebo, taking three tablets daily. We gathered information on gastrointestinal symptoms and bowel habits through a self-administered questionnaire, focusing especially on those who experienced digestive disturbances like mild dyspepsia or bloating.

The results were promising; those who took the synbiotic product reported significant improvements in their overall gastrointestinal well-being and bowel movements. Interestingly, we also noted a reduction in a specific immune marker, L-selectin, in the synbiotic group, which could indicate a favorable shift in their immune profile. However, while the improvements in gut health were noteworthy, none of the other immunological parameters were significantly altered.

In summary, this study suggests that including Lactobacillus acidophilus as part of a synbiotic supplement can lead to better digestive comfort and may influence immune-related markers positively. However, pinpointing the exact effect of this specific strain on indigestion alone is challenging, given the multi-strain nature of the synbiotic treatment.
9.5
Keeps reflux away
Most Useful Review
This is a great product. We've taken acidophilus for years, and this brand is excellent compared to others we've tried. It helps keep acid reflux and indigestion at bay.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Lactobacillus acidophilus shows promise in autoimmune management
New Lactobacillus acidophilus isolates reduce the release of leptin by murine adipocytes leading to lower interferon-gamma production.
Most Relevant Research
We explored how specific Lactobacillus acidophilus strains can impact autoimmune disorders by reducing leptin production in mice. In our study, we compared the effects of CBA4P and other lactobacilli on adipocytes from mice sensitive to Th1 immune diseases.

Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
9.5
Gut health improvement
Most Useful Review
This product has really helped settle my children's gut issues, especially when taken on an empty stomach. After finishing the last capsule, I'm ordering two more containers.

Bloating details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.2
USERS' SCORE
Good
Based on 13 Reviews
8.6
9
Lactobacillus improves bloating symptoms
Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study.
Most Relevant Research
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
9.5
Bloating relief
Most Useful Review
They work wonderfully! After identifying a lack of useful microflora in my analysis, I opted for these bacteria from NOW Foods. I’m pleased with this brand. Since starting the two-week course, I've noticed that the bloating has subsided, and my complexion has improved significantly.

Acne details

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.5
7
Probiotics and acne connection explored
Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine.
Most Relevant Research
We explored the connection between probiotics, particularly Lactobacillus acidophilus, and acne, delving into the gut-brain-skin axis. This long-standing theory suggests that our emotional states can impact gut health, potentially leading to acne due to inflammation and other factors.

Recent scientific studies indicate that probiotics might affect acne severity by influencing inflammation and even mood. However, while the relationship between gut health and skin clarity is intriguing, we did not find strong evidence conclusively linking Lactobacillus acidophilus treatment to significant improvements in acne.
10
Tremendous skin improvement
Most Useful Review
My skin and my daughter’s skin have significantly cleared up. There are no longer any signs of hormonal acne! I plan on ordering more. This product has also helped clean up my digestive tract. I will be continuing to purchase it.

Menopause details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
MENOLACTO alleviates menopausal symptoms
The Effect of YT1 (MENOLACTO) on Improving Menopausal Symptoms: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.
Most Relevant Research
This study explored how MENOLACTO, a form of lactobacillus acidophilus, can help women manage menopausal symptoms. We conducted a rigorous, randomized, double-blinded, placebo-controlled trial with women aged 40 to 60, measuring the effectiveness through various symptom scores and quality of life assessments.

After 12 weeks, we observed a significant decrease in total menopausal symptom scores compared to placebo. Participants also reported improvements across all quality of life metrics. However, we found no notable differences in hormone levels or endometrial thickness between the groups. Overall, MENOLACTO showed promise as a supportive option for alleviating menopause symptoms.
8.8
Feeling better
Most Useful Review
I have felt improvement since switching to this royal jelly. Five years ago, I became ill and suspect it might be menopause. After trying various treatments without success, I found this royal jelly has helped me feel naturally sleepy at night and more energised during the day. Though I still experience hot flashes, my anxiety has decreased, and my mental state feels more stable. I want to continue using it, but I’m devastated that sales seem to have ended.

Allergies details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 9 Reviews
8.3
9
Lactobacillus KBL409 reduces atopic dermatitis
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model.
Most Relevant Research
We explored the effects of Lactobacillus acidophilus KBL409 on atopic dermatitis (AD) using a house dust mite-induced mouse model. The treatment notably lowered dermatitis symptoms and reduced immune cell infiltration in the skin. Additionally, it decreased levels of specific immune markers and increased anti-inflammatory responses.

L. acidophilus KBL409 also positively influenced gut microbiota and certain metabolites. The findings suggest that this probiotic may offer a promising approach to managing AD through immune system modulation and gut health improvement.
8.3
Effective for allergies
Most Useful Review
I've tried many lactobacillus products but often suffered from allergies and diarrhoea. This product has been life-changing. No matter what I eat, including allergy-triggering foods, I no longer have diarrhoea.

Irritable Bowel Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 12 Reviews
8.2
9
Lactobacillus drink benefits IBS-C
Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink.
Most Relevant Research
We explored the impact of a Lactobacillus-containing cultured milk drink on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants consumed this drink daily while we assessed their clinical symptoms and inflammatory markers.

Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
8.3
Helps with diarrhea
Most Useful Review
I purchased two bottles of this product. Initially, I took one pill and then increased to one in the morning and two in the evening. It's really helpful for my irritable bowel syndrome and has also benefited an elder in my family with chronic diarrhoea.

Pelvic Pain details

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5.5
USERS' SCORE
Good
Based on 8 Reviews
8.2
7
Lactobacillus association with pelvic pain
Urinary Microbiome and Cytokine Levels in Women With Interstitial Cystitis.
Most Relevant Research
We examined the urinary microbiome of women with interstitial cystitis and found it less diverse and containing fewer Lactobacillus acidophilus compared to a control group.

This lack of Lactobacillus was linked to more severe symptoms and poor quality of life. While we noted some associations between higher inflammatory markers and the severity of symptoms, we didn’t see a clear causal relationship.

Essentially, we’re still unsure if the presence of Lactobacillus can effectively reduce pelvic pain in this context.
9.5
Effective relief
Most Useful Review
After trying various probiotics unsuccessfully for years, this one really worked for me. I experienced significant gas soon after taking it, which indicated that it was effective. Most importantly, I was finally pain-free from my digestive issues.

Constipation details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 45 Reviews
8.1
9
Probiotics improve constipation symptoms
Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial.
Most Relevant Research
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.

The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
10
Daily bowel movement
Most Useful Review
The effect is remarkable. I have tried numerous lactic acid bacteria and probiotics, yet nothing matches this product. Initially, I experienced constipation, but since using it, I now go daily. It's been a game-changer for my bowel health and will also assist those seeking to lose weight.

Eczema details

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8
9
Lactobacillus acidophilus helps eczema
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model.
Most Relevant Research
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.

Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
9.5
Eczema relief
Most Useful Review
For biotin therapy for hand eczema, I began taking it six months ago, alongside time-release vitamin C. I haven’t had eczema since and no longer need dermatological visits. Previously, I used cream and steroids. This treatment is affordable, and I recommend it to housewives and hairdressers who frequently work with water. However, I didn’t notice any effect on constipation.
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