Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
9
We investigated how Lactobacillus acidophilus might affect allergy responses using a mouse model allergic to bovine β-lactoglobulin. The mice received varying doses of heat-killed L. acidophilus over several weeks prior to allergen exposure.
Our findings revealed that this treatment significantly reduced allergic reactions, including less inflammation and lower levels of IgE. We observed shifts in immune markers indicating improved balance in immune responses.
However, while there were beneficial effects observed, the overall significance of these findings needs further research.
Our findings revealed that this treatment significantly reduced allergic reactions, including less inflammation and lower levels of IgE. We observed shifts in immune markers indicating improved balance in immune responses.
However, while there were beneficial effects observed, the overall significance of these findings needs further research.
Read More
9
Lactobacillus KBL409 reduces atopic dermatitis
We explored the effects of Lactobacillus acidophilus KBL409 on atopic dermatitis (AD) using a house dust mite-induced mouse model. The treatment notably lowered dermatitis symptoms and reduced immune cell infiltration in the skin. Additionally, it decreased levels of specific immune markers and increased anti-inflammatory responses.
L. acidophilus KBL409 also positively influenced gut microbiota and certain metabolites. The findings suggest that this probiotic may offer a promising approach to managing AD through immune system modulation and gut health improvement.
L. acidophilus KBL409 also positively influenced gut microbiota and certain metabolites. The findings suggest that this probiotic may offer a promising approach to managing AD through immune system modulation and gut health improvement.
Read More
9
We conducted a thorough investigation to see how Lactobacillus acidophilus L-92 affects skin symptoms in adults with atopic dermatitis. In this double-blind study involving 50 participants, we compared this probiotic against a placebo over 24 weeks.
Our findings showed that those taking L-92 experienced significant improvements in skin condition compared to the placebo group. There were reductions in symptoms and overall severity, with no adverse effects reported. This suggests that L-92 may help manage inflammation linked to allergies.
Our findings showed that those taking L-92 experienced significant improvements in skin condition compared to the placebo group. There were reductions in symptoms and overall severity, with no adverse effects reported. This suggests that L-92 may help manage inflammation linked to allergies.
Read More
Most Useful Reviews
9
Effective for allergies
1 people found this helpful
I've tried many lactobacillus products but often suffered from allergies and diarrhoea. This product has been life-changing. No matter what I eat, including allergy-triggering foods, I no longer have diarrhoea.
Read More
0
Allergic reaction
Unfortunately, I was allergic to casein due to delayed allergies. I purchased this as a remedy for candida, but it did not help and resulted in eczema.
Read More
7.5
Allergy relief
4 people found this helpful
Really helpful. Recommended by my chiropractor. It assists with allergies and digestion problems. Would definitely recommend.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
- All Researches
9
We examined if a specific blend of probiotics could alleviate symptoms of Allergic Rhinitis (AR). This randomized controlled trial compared a probiotic group to a placebo over eight weeks, tracking changes in allergy symptoms and gut health.
We found that those taking probiotics noted significant improvements in quality of life scores at all evaluated time points. Additionally, the probiotics seemed to alter gut bacteria favorably, reducing inflammation associated with allergies.
However, more research is necessary to fully understand these benefits and their long-term effects.
We found that those taking probiotics noted significant improvements in quality of life scores at all evaluated time points. Additionally, the probiotics seemed to alter gut bacteria favorably, reducing inflammation associated with allergies.
However, more research is necessary to fully understand these benefits and their long-term effects.
Read More
9
We investigated the effects of a symbiotic food supplement on individuals suffering from birch pollen allergy. Utilizing an allergen exposure chamber, we monitored patients’ responses before and after four months of daily intake.
Findings showed significant improvements in symptoms, overall well-being, and good safety. The combination of probiotics and prebiotics was effective in relieving allergy symptoms, highlighting its potential as a useful complementary approach in managing allergic rhinitis.
Findings showed significant improvements in symptoms, overall well-being, and good safety. The combination of probiotics and prebiotics was effective in relieving allergy symptoms, highlighting its potential as a useful complementary approach in managing allergic rhinitis.
Read More
9
We investigated how Lactobacillus acidophilus might affect allergy responses using a mouse model allergic to bovine β-lactoglobulin. The mice received varying doses of heat-killed L. acidophilus over several weeks prior to allergen exposure.
Our findings revealed that this treatment significantly reduced allergic reactions, including less inflammation and lower levels of IgE. We observed shifts in immune markers indicating improved balance in immune responses.
However, while there were beneficial effects observed, the overall significance of these findings needs further research.
Our findings revealed that this treatment significantly reduced allergic reactions, including less inflammation and lower levels of IgE. We observed shifts in immune markers indicating improved balance in immune responses.
However, while there were beneficial effects observed, the overall significance of these findings needs further research.
Read More
9
Lactobacillus KBL409 reduces atopic dermatitis
We explored the effects of Lactobacillus acidophilus KBL409 on atopic dermatitis (AD) using a house dust mite-induced mouse model. The treatment notably lowered dermatitis symptoms and reduced immune cell infiltration in the skin. Additionally, it decreased levels of specific immune markers and increased anti-inflammatory responses.
L. acidophilus KBL409 also positively influenced gut microbiota and certain metabolites. The findings suggest that this probiotic may offer a promising approach to managing AD through immune system modulation and gut health improvement.
L. acidophilus KBL409 also positively influenced gut microbiota and certain metabolites. The findings suggest that this probiotic may offer a promising approach to managing AD through immune system modulation and gut health improvement.
Read More
9
We investigated the effects of Lactobacillus acidophilus on allergies, particularly its peptidoglycan derived from dairy. In a mouse model of β-lactoglobulin allergy, we discovered that this peptidoglycan helped lower IgE production and promoted a healthier immune response. It also appeared to influence specific immune signaling pathways that help manage allergic reactions.
However, while the results showed promise, they were conducted in a controlled lab setting and further studies are needed to understand how these effects translate to humans.
However, while the results showed promise, they were conducted in a controlled lab setting and further studies are needed to understand how these effects translate to humans.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for allergies
1 people found this helpful
I've tried many lactobacillus products but often suffered from allergies and diarrhoea. This product has been life-changing. No matter what I eat, including allergy-triggering foods, I no longer have diarrhoea.
Read More
0
Allergic reaction
Unfortunately, I was allergic to casein due to delayed allergies. I purchased this as a remedy for candida, but it did not help and resulted in eczema.
Read More
7.5
Allergy relief
4 people found this helpful
Really helpful. Recommended by my chiropractor. It assists with allergies and digestion problems. Would definitely recommend.
Read More
9
Improved digestion
1 people found this helpful
Excellent! Great for those suffering from gluten and grain allergies. It considerably improved my digestion.
Read More
7.5
Supports allergies
1 people found this helpful
I started using NOW Foods Acidophilus after antibiotics disrupted my gut flora. I noticed significant improvements in digestion and fewer allergies. They are easy to swallow, gluten-free, and do not require refrigeration, making them perfect for travelling. I'm very pleased and will continue using them.
Read More
Frequently Asked Questions
7.5
Supports allergies
1 people found this helpful
I started using NOW Foods Acidophilus after antibiotics disrupted my gut flora. I noticed significant improvements in digestion and fewer allergies. They are easy to swallow, gluten-free, and do not require refrigeration, making them perfect for travelling. I'm very pleased and will continue using them.
7.5
Allergy relief
4 people found this helpful
Really helpful. Recommended by my chiropractor. It assists with allergies and digestion problems. Would definitely recommend.
9
Effective for allergies
1 people found this helpful
I've tried many lactobacillus products but often suffered from allergies and diarrhoea. This product has been life-changing. No matter what I eat, including allergy-triggering foods, I no longer have diarrhoea.
9
Digestive improvement
Excellent quality product. I experienced no allergies or negative reactions. The capsules are of a suitable size, and my digestive issues have improved significantly. My absorption of vitamins has also enhanced overall health.
0
Allergic reaction
Unfortunately, I was allergic to casein due to delayed allergies. I purchased this as a remedy for candida, but it did not help and resulted in eczema.
7.5
Enhances immunity
1 people found this helpful
Probiotics are essential for gut health and can alleviate allergy symptoms. They maintain intestinal balance and improve digestion. Regular intake boosts the immune system and positively impacts mental health. They are beneficial for overall health and well-being.
9
We examined if a specific blend of probiotics could alleviate symptoms of Allergic Rhinitis (AR). This randomized controlled trial compared a probiotic group to a placebo over eight weeks, tracking changes in allergy symptoms and gut health.
We found that those taking probiotics noted significant improvements in quality of life scores at all evaluated time points. Additionally, the probiotics seemed to alter gut bacteria favorably, reducing inflammation associated with allergies.
However, more research is necessary to fully understand these benefits and their long-term effects.
We found that those taking probiotics noted significant improvements in quality of life scores at all evaluated time points. Additionally, the probiotics seemed to alter gut bacteria favorably, reducing inflammation associated with allergies.
However, more research is necessary to fully understand these benefits and their long-term effects.
9
We investigated the effects of a symbiotic food supplement on individuals suffering from birch pollen allergy. Utilizing an allergen exposure chamber, we monitored patients’ responses before and after four months of daily intake.
Findings showed significant improvements in symptoms, overall well-being, and good safety. The combination of probiotics and prebiotics was effective in relieving allergy symptoms, highlighting its potential as a useful complementary approach in managing allergic rhinitis.
Findings showed significant improvements in symptoms, overall well-being, and good safety. The combination of probiotics and prebiotics was effective in relieving allergy symptoms, highlighting its potential as a useful complementary approach in managing allergic rhinitis.
8
Lactobacillus acidophilus aids allergy management
We explored how Lactobacillus acidophilus can influence allergic reactions, specifically in mice with cow's milk protein allergy.
Over four weeks, these mice received different doses of L. acidophilus prior to allergen exposure. Results indicated that treatment reduced hypersensitivity responses and improved gut health by boosting microbiota diversity and short-chain fatty acids.
Furthermore, L. acidophilus increased the expression of beneficial receptors, suggesting it might help mitigate allergic inflammation through improved gut function.
Over four weeks, these mice received different doses of L. acidophilus prior to allergen exposure. Results indicated that treatment reduced hypersensitivity responses and improved gut health by boosting microbiota diversity and short-chain fatty acids.
Furthermore, L. acidophilus increased the expression of beneficial receptors, suggesting it might help mitigate allergic inflammation through improved gut function.
7
We found that when pregnant women took a probiotic blend, including Lactobacillus acidophilus, it helped lower certain immune cells called Th22 in their newborns.
This reduction seemed to play a role in preventing atopic dermatitis (AD) in babies during their first two years of life.
Babies born to mothers who received probiotics showed a significantly lower proportion of Th22 cells compared to those whose mothers took a placebo, suggesting this specific cell type may influence allergy development.
This reduction seemed to play a role in preventing atopic dermatitis (AD) in babies during their first two years of life.
Babies born to mothers who received probiotics showed a significantly lower proportion of Th22 cells compared to those whose mothers took a placebo, suggesting this specific cell type may influence allergy development.
References
- Lungaro L, Malfa P, Manza F, Costanzini A, Valentini G, et al. Clinical Efficacy of Probiotics for Allergic Rhinitis: Results of an Exploratory Randomized Controlled Trial. Nutrients. 2024;16. 10.3390/nu16234173
- Bergmann KC, Krause L, Hiller J, Becker S, Kugler S, et al. First evaluation of a symbiotic food supplement in an allergen exposure chamber in birch pollen allergic patients. World Allergy Organ J. 2021;14:100494. 10.1016/j.waojou.2020.100494
- Ni WW, Zhang QM, Zhang X, Li Y, Yu SS, et al. Modulation effect of Lactobacillus acidophilus KLDS 1.0738 on gut microbiota and TLR4 expression in β-lactoglobulin-induced allergic mice model. Allergol Immunopathol (Madr). 2020;48:149. 10.1016/j.aller.2019.06.002
- Wang JJ, Zhang QM, Ni WW, Zhang X, Li Y, et al. Modulatory effect of Lactobacillus acidophilus KLDS 1.0738 on intestinal short-chain fatty acids metabolism and GPR41/43 expression in β-lactoglobulin-sensitized mice. Microbiol Immunol. 2019;63:303. 10.1111/1348-0421.12723
- Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, et al. Additive effect of L-92 on children with atopic dermatitis concomitant with food allergy. Asia Pac Allergy. 2019;9:e18. 10.5415/apallergy.2019.9.e18
- Wang JJ, Li SH, Li AL, Zhang QM, Ni WW, et al. Effect of Lactobacillus acidophilus KLDS 1.0738 on miRNA expression in in vitro and in vivo models of β-lactoglobulin allergy. Biosci Biotechnol Biochem. 2018;82:1955. 10.1080/09168451.2018.1495551
- Toomer OT, Ferguson M, Pereira M, Do A, Bigley E, et al. Maternal and postnatal dietary probiotic supplementation enhances splenic regulatory T helper cell population and reduces ovalbumin allergen-induced hypersensitivity responses in mice. Immunobiology. 2014;219:367. 10.1016/j.imbio.2014.01.003
- Li AL, Meng XC, Duan CC, Huo GC, Zheng QL, et al. Suppressive effects of oral administration of heat-killed Lactobacillus acidophilus on T helper-17 immune responses in a bovine β-lactoglobulin-sensitized mice model. Biol Pharm Bull. 2013;36:202.
- Shah MM, Miyamoto Y, Yamada Y, Yamashita H, Tanaka H, et al. Orally supplemented Lactobacillus acidophilus strain L-92 inhibits passive and active cutaneous anaphylaxis as well as 2,4-dinitroflurobenzene and mite fecal antigen induced atopic dermatitis-like skin lesions in mice. Microbiol Immunol. 2010;54:523. 10.1111/j.1348-0421.2010.00251.x
- Penders J, Thijs C, Mommers M, Stobberingh EE, Dompeling E, et al. Intestinal lactobacilli and the DC-SIGN gene for their recognition by dendritic cells play a role in the aetiology of allergic manifestations. Microbiology (Reading). 2010;156:3298. 10.1099/mic.0.042069-0
- Kim WK, Jang YJ, Park S, Min SG, Kwon H, et al. Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model. J Microbiol. 2024;62:91. 10.1007/s12275-024-00104-5
- Husein-ElAhmed H, Steinhoff M. Effects of probiotic supplementation in adult with atopic dermatitis: a systematic review with meta-analysis. Clin Exp Dermatol. 2023;49:46. 10.1093/ced/llad318
- Li A, Yang J, Zhang C, Chi H, Zhang C, et al. Lactobacillus acidophilus KLDS 1.0738 inhibits TLR4/NF-κB inflammatory pathway in β-lactoglobulin-induced macrophages via modulating miR-146a. J Food Biochem. 2021;45:e13662. 10.1111/jfbc.13662
- Tan-Lim CSC, Esteban-Ipac NAR, Mantaring JBV, Chan Shih Yen E, Recto MST, et al. Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:124. 10.1111/pai.13305
- Li AL, Sun YQ, Du P, Meng XC, Guo L, et al. The Effect of Lactobacillus actobacillus Peptidoglycan on Bovine β-Lactoglobulin-Sensitized Mice via TLR2/NF-κB Pathway. Iran J Allergy Asthma Immunol. 2017;16:147.
- Rø ADB, Simpson MR, Rø TB, Storrø O, Johnsen R, et al. Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation. Clin Exp Allergy. 2017;47:1014. 10.1111/cea.12930
- Gelardi M, De Luca C, Taliente S, Fiorella ML, Quaranta N, et al. Adjuvant treatment with a symbiotic in patients with inflammatory non-allergic rhinitis. J Biol Regul Homeost Agents. 2017;31:201.
- Shen X, Li M, Shi L, Ling N, He M, et al. [The Immunomodulatory and Anti-allergy Effects of Lactobacilli]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2016;47:192.
- Yamamoto K, Yokoyama K, Matsukawa T, Kato S, Kato S, et al. Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis. J Dairy Sci. 2016;99:5039. 10.3168/jds.2015-10605
- Shandilya UK, Sharma A, Kapila R, Kansal VK. Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates immunoglobulin levels and cytokines expression in whey proteins sensitised mice. J Sci Food Agric. 2016;96:3180. 10.1002/jsfa.7497
- Simpson MR, Dotterud CK, Storrø O, Johnsen R, Øien T. Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial. BMC Dermatol. 2015;15:13. 10.1186/s12895-015-0030-1
