' 
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
8
Probiotics help rheumatoid arthritis symptoms
Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial.
Highly relevant clinical study
This study explored how probiotic supplementation affects patients with rheumatoid arthritis (RA) over eight weeks.
We analyzed the results from sixty patients, split into groups receiving either probiotics or placebo.
The findings showed that those taking probiotics experienced a notable improvement in joint health, as well as reductions in insulin levels and inflammation markers.
We observed that the probiotics had a positive impact on overall metabolic health, significantly benefitting those with RA.
We analyzed the results from sixty patients, split into groups receiving either probiotics or placebo.
The findings showed that those taking probiotics experienced a notable improvement in joint health, as well as reductions in insulin levels and inflammation markers.
We observed that the probiotics had a positive impact on overall metabolic health, significantly benefitting those with RA.
Read More
9
Lactobacillus acidophilus shows promise in autoimmune management
New Lactobacillus acidophilus isolates reduce the release of leptin by murine adipocytes leading to lower interferon-gamma production.
High relevance for autoimmune treatment
We explored how specific Lactobacillus acidophilus strains can impact autoimmune disorders by reducing leptin production in mice. In our study, we compared the effects of CBA4P and other lactobacilli on adipocytes from mice sensitive to Th1 immune diseases.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
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8
Probiotics reduce oral candidiasis
Probiotics as a prophylaxis to prevent oral candidiasis in patients with Sjogren's syndrome: a double-blinded, placebo-controlled, randomized trial.
Study shows probiotics are effective
This study looked at how probiotics help reduce oral candidiasis in Sjögren's syndrome patients. We divided 32 participants into two groups: one received probiotics, while the other got a placebo for five weeks.
By the end of the trial, those taking probiotics showed a significant decrease in candidal growth, unlike the placebo group who did not see any notable change. This suggests that probiotics could be a promising alternative for preventing oral thrush in these patients.
By the end of the trial, those taking probiotics showed a significant decrease in candidal growth, unlike the placebo group who did not see any notable change. This suggests that probiotics could be a promising alternative for preventing oral thrush in these patients.
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Most Useful Reviews
9.5
Gut health improvement
This product has really helped settle my children's gut issues, especially when taken on an empty stomach. After finishing the last capsule, I'm ordering two more containers.
Read More
8.8
Supports health resilience
Now Foods provides a sustainable probiotic that has maintained our health despite my husband's Crohn's Disease and my autoimmune disorder. We've been using it for several months.
Read More
9
Digestive support noted
This high-quality supplement has been beneficial for my digestion and has alleviated constipation, making it a great help for my autoimmune disorder and other digestive issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8
- All Researches
9
LA enhances Tacrolimus efficacy
Supplementation Exerts a Synergistic Effect on Tacrolimus Efficacy by Modulating Th17/Treg Balance in Lupus-Prone Mice the SIGNR3 Pathway.
High relevance for autoimmune studies
We investigated the effects of combining lactic acid (LA) with Tacrolimus (Tac) on treating lupus in mice. By administering both treatments, we observed an improvement in gut health and a balanced ratio of T cell subsets.
The combination therapy significantly decreased harmful autoantibody levels and improved kidney health. Additionally, it boosted regulatory T (Treg) cells while reducing T helper 17 (Th17) cells, ultimately enhancing the effectiveness of Tac for managing lupus-like conditions.
The combination therapy significantly decreased harmful autoantibody levels and improved kidney health. Additionally, it boosted regulatory T (Treg) cells while reducing T helper 17 (Th17) cells, ultimately enhancing the effectiveness of Tac for managing lupus-like conditions.
Read More
9
Probiotic shows promise for rheumatoid arthritis
A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis.
Scores implications for future treatment
We assessed how Lactobacillus casei, a type of probiotic bacteria, impacted autoimmune responses in rats with rheumatoid arthritis. The treatment showed promise, significantly reducing joint swelling and preventing bone destruction by restoring the gut microbiome.
The analysis revealed that L. casei not only helped correct microbiome imbalances but also lowered inflammation indicators. Though these results are promising, further investigation is needed to confirm the effectiveness of probiotics in human arthritis treatment.
The analysis revealed that L. casei not only helped correct microbiome imbalances but also lowered inflammation indicators. Though these results are promising, further investigation is needed to confirm the effectiveness of probiotics in human arthritis treatment.
Read More
9
Synbiotics improve rheumatoid arthritis outcomes
Synbiotic supplementation and the effects on clinical and metabolic responses in patients with rheumatoid arthritis: a randomised, double-blind, placebo-controlled trial.
High relevance for autoimmune therapies.
We examined how synbiotic supplementation impacts patients with rheumatoid arthritis over 8 weeks. In our double-blind, placebo-controlled trial involving 54 participants, we found that those taking synbiotics experienced significant improvements. These included lower inflammation markers such as hs-CRP and better joint pain scores on the DAS-28 and VAS.
Additionally, improvements were noted in insulin resistance and oxidative stress markers, hinting at potential metabolic benefits. Overall, our findings suggest that synbiotic treatment could play a role in managing some aspects of rheumatoid arthritis effectively.
Additionally, improvements were noted in insulin resistance and oxidative stress markers, hinting at potential metabolic benefits. Overall, our findings suggest that synbiotic treatment could play a role in managing some aspects of rheumatoid arthritis effectively.
Read More
9
Probiotic IRT5 reduces diabetes effects
Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics.
Relevant for diabetes research
We examined how a special probiotic mix, known as IRT5, affects autoimmune diabetes in non-obese diabetic (NOD) mice. Administered frequently over 36 weeks, this combination not only reduced diabetes incidence but also lowered insulitis scores and increased insulin-producing β-cell mass.
Additionally, IRT5 improved gut health and changed the makeup of immune cells in the pancreas and intestines. While some immune responses stayed the same, the shift towards more gut-focused regulatory T cells suggests it could be a promising treatment for type 1 diabetes.
Additionally, IRT5 improved gut health and changed the makeup of immune cells in the pancreas and intestines. While some immune responses stayed the same, the shift towards more gut-focused regulatory T cells suggests it could be a promising treatment for type 1 diabetes.
Read More
9
Synbiotics improve rheumatoid arthritis symptoms
Synbiotic supplementation and the effects on clinical and metabolic responses in patients with rheumatoid arthritis: a randomised, double-blind, placebo-controlled trial.
High relevance; significant findings
We investigated how synbiotic supplementation affects patients with rheumatoid arthritis (RA). In an 8-week, randomized, double-blind trial involving 54 participants, we compared the outcomes of those taking synbiotic capsules with a placebo group.
After the trial, those who received synbiotics showed a significant drop in inflammation markers and pain levels. Additionally, improvements were observed in insulin resistance and overall metabolic responses.
These findings suggest that synbiotics might benefit individuals managing RA by reducing inflammation and enhancing metabolic health.
After the trial, those who received synbiotics showed a significant drop in inflammation markers and pain levels. Additionally, improvements were observed in insulin resistance and overall metabolic responses.
These findings suggest that synbiotics might benefit individuals managing RA by reducing inflammation and enhancing metabolic health.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Gut health improvement
This product has really helped settle my children's gut issues, especially when taken on an empty stomach. After finishing the last capsule, I'm ordering two more containers.
8.8
Supports health resilience
Now Foods provides a sustainable probiotic that has maintained our health despite my husband's Crohn's Disease and my autoimmune disorder. We've been using it for several months.
9
Digestive support noted
This high-quality supplement has been beneficial for my digestion and has alleviated constipation, making it a great help for my autoimmune disorder and other digestive issues.
