Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.1
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
9
We explored the effectiveness of a probiotic mix, including Lactobacillus acidophilus, in preventing recurrent urinary tract infections (UTIs) in children. In a study involving 181 children aged 4 months to 5 years, half received the probiotics while the other half received a placebo over 18 months.
The results were significant. The probiotic group had a higher percentage of UTI-free patients and a longer median time before recurrence compared to the placebo group. This indicates that probiotics could be a helpful non-antibiotic option for preventing UTI recurrences in young children.
The results were significant. The probiotic group had a higher percentage of UTI-free patients and a longer median time before recurrence compared to the placebo group. This indicates that probiotics could be a helpful non-antibiotic option for preventing UTI recurrences in young children.
3
Probiotics as effective as antibiotics
We examined the role of probiotics in preventing urinary tract infections (UTIs) among children with persistent primary vesicoureteral reflux (VUR). In a well-structured study, 120 children were randomly split into two groups—one receiving Lactobacillus acidophilus and the other conventional antibiotics.
The results showed no significant difference in UTI recurrence rates between the probiotics group (18.3%) and the antibiotics group (21.6%). Further analysis, considering various factors, revealed that probiotics did not outperform antibiotics. In short, using probiotics for UTI prevention in these children appears equally effective as the traditional antibiotic approach.
The results showed no significant difference in UTI recurrence rates between the probiotics group (18.3%) and the antibiotics group (21.6%). Further analysis, considering various factors, revealed that probiotics did not outperform antibiotics. In short, using probiotics for UTI prevention in these children appears equally effective as the traditional antibiotic approach.
8
We examined how single and mixed probiotic strains affect common urinary tract infections (UTIs) caused by E. coli and E. faecalis. Through various tests, we found that all probiotic types could inhibit these pathogens. While L. acidophilus and L. fermentum were particularly effective, we discovered that mixed probiotics did not significantly outperform individual strains. This suggests that probiotics can potentially help in reducing UTIs by preventing pathogen growth, although their effectiveness in mixtures isn’t markedly superior to single strains.
Most Useful Reviews
9
No infections experienced
4 people found this helpful
They WORK!!! I usually wouldn't write a review, but this product is amazing. I've been searching for something to maintain a healthy balance, and this is it. I take three a day on an empty stomach, and it has kept me perfectly balanced. I suffered from urinary tract infections due to antibiotics disrupting my balance, but since I started taking these, I haven't had any infections. I would highly recommend this product.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.1
- All Researches
9
We explored the effectiveness of a probiotic mix, including Lactobacillus acidophilus, in preventing recurrent urinary tract infections (UTIs) in children. In a study involving 181 children aged 4 months to 5 years, half received the probiotics while the other half received a placebo over 18 months.
The results were significant. The probiotic group had a higher percentage of UTI-free patients and a longer median time before recurrence compared to the placebo group. This indicates that probiotics could be a helpful non-antibiotic option for preventing UTI recurrences in young children.
The results were significant. The probiotic group had a higher percentage of UTI-free patients and a longer median time before recurrence compared to the placebo group. This indicates that probiotics could be a helpful non-antibiotic option for preventing UTI recurrences in young children.
9
We aimed to investigate how a combination of D-mannose, Salicin, and Lactobacillus acidophilus affects recurrent urinary tract infections caused by E. coli. Our study involved 85 patients, assessing their symptoms before and after an eight-week treatment period. By the end, participants reported a significant reduction in pain and frequency of symptoms.
While our results are promising, showing improvements in urinary symptoms, we acknowledge that further research is necessary to fully validate these findings. Thus, though acidophilus appears beneficial, more extensive studies could enhance our understanding.
While our results are promising, showing improvements in urinary symptoms, we acknowledge that further research is necessary to fully validate these findings. Thus, though acidophilus appears beneficial, more extensive studies could enhance our understanding.
8
We explored if Lactobacillus probiotics could prevent urinary tract infections (UTIs) by inhibiting harmful bacteria. Our study tested three strains—Lactobacillus salivarius, L. plantarum, and L. acidophilus—against various uropathogens' ability to stick to bladder cells.
The results revealed that L. salivarius and L. acidophilus showed promising inhibition rates, effectively reducing uropathogen adherence by up to 53.7%. Meanwhile, L. plantarum did not exhibit significant anti-adherence effects. These findings suggest that specific Lactobacillus strains might help in UTI prevention.
The results revealed that L. salivarius and L. acidophilus showed promising inhibition rates, effectively reducing uropathogen adherence by up to 53.7%. Meanwhile, L. plantarum did not exhibit significant anti-adherence effects. These findings suggest that specific Lactobacillus strains might help in UTI prevention.
8
We examined the potential of locally isolated Lactobacillus species in fighting antibiotic-resistant bacteria linked to urinary tract infections (UTIs). Our study involved lactic acid bacteria sourced from spoiled fruits and vegetables, which showed significant antimicrobial activity against six out of seven tested pathogenic bacteria.
Specifically, strains like L. fermentum and L. plantarum demonstrated impressive abilities to inhibit growth of harmful E. coli and E. faecalis. These findings suggest that Lactobacillus could be a promising option for controlling UTIs, especially in the face of increasing antibiotic resistance.
Specifically, strains like L. fermentum and L. plantarum demonstrated impressive abilities to inhibit growth of harmful E. coli and E. faecalis. These findings suggest that Lactobacillus could be a promising option for controlling UTIs, especially in the face of increasing antibiotic resistance.
8
We examined how single and mixed probiotic strains affect common urinary tract infections (UTIs) caused by E. coli and E. faecalis. Through various tests, we found that all probiotic types could inhibit these pathogens. While L. acidophilus and L. fermentum were particularly effective, we discovered that mixed probiotics did not significantly outperform individual strains. This suggests that probiotics can potentially help in reducing UTIs by preventing pathogen growth, although their effectiveness in mixtures isn’t markedly superior to single strains.
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
No infections experienced
4 people found this helpful
They WORK!!! I usually wouldn't write a review, but this product is amazing. I've been searching for something to maintain a healthy balance, and this is it. I take three a day on an empty stomach, and it has kept me perfectly balanced. I suffered from urinary tract infections due to antibiotics disrupting my balance, but since I started taking these, I haven't had any infections. I would highly recommend this product.
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Sadeghi-Bojd S, Naghshizadian R, Mazaheri M, Ghane Sharbaf F, Assadi F. Efficacy of Probiotic Prophylaxis After The First Febrile Urinary Tract Infection in Children With Normal Urinary Tracts. J Pediatric Infect Dis Soc. 2020;9:305. doi:10.1093/jpids/piz025
- Del Popolo G, Nelli F. Recurrent bacterial symptomatic cystitis: A pilot study on a new natural option for treatment. Arch Ital Urol Androl. 2018;90:101. doi:10.4081/aiua.2018.2.101
- de Llano DG, Arroyo A, Cárdenas N, Rodríguez JM, Moreno-Arribas MV, et al. Strain-specific inhibition of the adherence of uropathogenic bacteria to bladder cells by probiotic Lactobacillus spp. Pathog Dis. 2017;75. doi:10.1093/femspd/ftx043
- Shim YH, Lee SJ, Lee JW. Antimicrobial activity of lactobacillus strains against uropathogens. Pediatr Int. 2016;58:1009. doi:10.1111/ped.12949
- Manzoor A, Ul-Haq I, Baig S, Qazi JI, Seratlic S. Efficacy of Locally Isolated Lactic Acid Bacteria Against Antibiotic-Resistant Uropathogens. Jundishapur J Microbiol. 2016;9:e18952. doi:10.5812/jjm.18952
- Lee SJ, Lee JW. Probiotics prophylaxis in infants with primary vesicoureteral reflux. Pediatr Nephrol. 2015;30:609. doi:10.1007/s00467-014-2988-z
- Mohseni MJ, Aryan Z, Emamzadeh-Fard S, Paydary K, Mofid V, et al. Combination of probiotics and antibiotics in the prevention of recurrent urinary tract infection in children. Iran J Pediatr. 2013;23:430.
- Chapman CM, Gibson GR, Todd S, Rowland I. Comparative in vitro inhibition of urinary tract pathogens by single- and multi-strain probiotics. Eur J Nutr. 2013;52:1669. doi:10.1007/s00394-013-0501-2
- Lee SJ, Shim YH, Cho SJ, Lee JW. Probiotics prophylaxis in children with persistent primary vesicoureteral reflux. Pediatr Nephrol. 2007;22:1315.
- Juárez Tomás MS, Ocaña VS, Wiese B, Nader-Macías ME. Growth and lactic acid production by vaginal Lactobacillus acidophilus CRL 1259, and inhibition of uropathogenic Escherichia coli. J Med Microbiol. 2003;52:1117. doi:10.1099/jmm.0.05155-0
- Velraeds MM, van de Belt-Gritter B, van der Mei HC, Reid G, Busscher HJ. Interference in initial adhesion of uropathogenic bacteria and yeasts to silicone rubber by a Lactobacillus acidophilus biosurfactant. J Med Microbiol. 1998;47:1081.
- Reid G, Bruce AW, McGroarty JA, Cheng KJ, Costerton JW. Is there a role for lactobacilli in prevention of urogenital and intestinal infections?. Clin Microbiol Rev. 1990;3:335.
- Mahgoub MA, Abbass AAG, Abaza AF, Shoukry MS. Probiotic lactic acid bacteria as a means of preventing in vitro urinary catheter colonization and biofilm formation. J Egypt Public Health Assoc. 2023;97:30. doi:10.1186/s42506-022-00124-2
- Rodrigues F, Maia MJ, das Neves J, Sarmento B, Amaral MH, et al. Vaginal suppositories containing Lactobacillus acidophilus: development and characterization. Drug Dev Ind Pharm. 2015;41:1518. doi:10.3109/03639045.2014.963864
